三种不同口腔矫治器对睡眠磨牙症活动的影响:一年纵向队列研究。

IF 2.8 4区 医学 Q2 PHARMACOLOGY & PHARMACY Current drug delivery Pub Date : 2024-01-01 DOI:10.2174/1567201819666220519123754
Andrea Bargellini, Tommaso Castroflorio, Vanessa Graziano, Giovanni Cugliari, Andrea Deregibus
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引用次数: 0

摘要

背景已经提出了不同的口腔矫治器(OA)来控制睡眠磨牙症(SB)对口腔正畸系统的有害影响。目的本研究的目的是评估不同OAs对SB活动和咀嚼肌活动(sMMA)的影响。方法对51名患有SB的患者(21M,30F,平均年龄26,5±3,5)进行纵向队列研究,这些患者使用经验证的便携式EMG-ECG holter进行诊断,并佩戴不同的OAs:咬合夹板,在分娩后1周、1个月、3个月、6个月和12个月,对带金属咬合和透明矫正器的功能性矫治器进行随访。对照组16名未接受治疗的SB患者(6 M,10 F,平均年龄27.1±1.4)作为参考。进行多元回归分析以估计各组之间的差异。显著性设定为P值<0.05。结果咬合夹板在分娩后1周、3个月、6个月和12个月降低了睡眠磨牙症指数,而功能矫治器仅在12个月后降低。咬合夹板仅在分娩后第一周减少了一般阶段性收缩,在分娩后1周、3个月和6个月减少了与睡眠磨牙症相关的阶段性收缩。12个月后没有显著减少。佩戴透明矫正器的患者在6个月和12个月后,全身强直性收缩减少。结论树脂和金属咬可降低睡眠磨牙症指数,树脂咬可降低与睡眠磨牙病相关的阶段性收缩。清晰的矫正器不会影响睡眠磨牙症指数,但可以减少紧张性收缩。
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Effects on Sleep Bruxism Activity of Three Different Oral Appliances: One Year Longitudinal Cohort Study.

Background: Different oral appliances (OAs) have been proposed to control sleep bruxism (SB) detrimental effects on the stomatognathic system.

Objective: The aim of the study was to evaluate the effect of different OAs on SB activity and masticatory muscle activity (sMMA) measured by EMG.

Methods: This longitudinal cohort study was conducted on 51 patients (21 M, 30 F, mean age 26,5 ± 3,5) suffering from SB diagnosed with a validated portable EMG-ECG holter and wearing different OAs: occlusal splints, functional appliance with metallic bites and clear aligners followed after 1 week, 1 month, 3 months, 6 months and 12 months from delivery. A control group of 16 non-treated SB patients (6 M, 10 F mean age 27,1 ± 1,4) was used as a reference. A multiple regression analysis was performed to estimate the differences between groups. The level of significance was set as P value <0,05.

Results: Occlusal splint reduced sleep bruxism index after 1 week, 3, 6 and 12 months from delivery while functional appliance only after 12 months. Occlusal splints reduced general phasic contractions only in the first week and sleep bruxism-related phasic contractions at 1 week, 3 and 6 months after delivery with no significant reductions after 12 months. Patients wearing clear aligners showed a reduction in general tonic contractions after 6 and 12 months.

Conclusion: Resin and metal bites can reduce sleep bruxism index, while resin bites can reduce sleep bruxism-related phasic contractions. Clear aligners do not influence sleep bruxism index but can reduce tonic contractions.

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来源期刊
Current drug delivery
Current drug delivery PHARMACOLOGY & PHARMACY-
CiteScore
5.10
自引率
4.20%
发文量
170
期刊介绍: Current Drug Delivery aims to publish peer-reviewed articles, research articles, short and in-depth reviews, and drug clinical trials studies in the rapidly developing field of drug delivery. Modern drug research aims to build delivery properties of a drug at the design phase, however in many cases this idea cannot be met and the development of delivery systems becomes as important as the development of the drugs themselves. The journal aims to cover the latest outstanding developments in drug and vaccine delivery employing physical, physico-chemical and chemical methods. The drugs include a wide range of bioactive compounds from simple pharmaceuticals to peptides, proteins, nucleotides, nucleosides and sugars. The journal will also report progress in the fields of transport routes and mechanisms including efflux proteins and multi-drug resistance. The journal is essential for all pharmaceutical scientists involved in drug design, development and delivery.
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