从环境到基因表达:表观遗传学与心理健康障碍的发展

Jennings Hernandez
{"title":"从环境到基因表达:表观遗传学与心理健康障碍的发展","authors":"Jennings Hernandez","doi":"10.9734/indj/2023/v20i2391","DOIUrl":null,"url":null,"abstract":"Psychiatric disorders have multifaceted origins, involving a combination of genetic and environmental factors that contribute significantly to their development. In recent times, researchers have emphasized the role of epigenetic mechanisms as the underlying molecular foundation for how environmental factors influence biological processes. Consequently, the field of epigenetics has gained growing prominence within the realm of psychiatry as a means to understand these intricate connections. This qualitative research paper explores the role of epigenetics in mental health disorders, focusing on the impact of environmental factors on gene expression. By examining the complex interplay between nature and nurture, the study provides insights into the influence of epigenetic modifications on psychiatric conditions such as schizophrenia, bipolar disorder, and post-traumatic stress disorder (PTSD). We performed semi-structured interviews with a broad range of psychiatric, genetic, and epigenetic specialists. In order to find pertinent studies looking at how epigenetic changes affect psychiatric diseases, including schizophrenia, bipolar disorder, and PTSD, a systematic literature analysis was carried out. Additionally, the paper discusses the potential implications of epigenetic research for personalized treatment approaches and early intervention strategies. Through a comprehensive literature review and qualitative analysis of expert interviews, this study enhances our understanding of the intricate relationship between epigenetics and mental health.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"From Environment to Gene Expression: Epigenetics and the Development of Mental Health Disorders\",\"authors\":\"Jennings Hernandez\",\"doi\":\"10.9734/indj/2023/v20i2391\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Psychiatric disorders have multifaceted origins, involving a combination of genetic and environmental factors that contribute significantly to their development. In recent times, researchers have emphasized the role of epigenetic mechanisms as the underlying molecular foundation for how environmental factors influence biological processes. Consequently, the field of epigenetics has gained growing prominence within the realm of psychiatry as a means to understand these intricate connections. This qualitative research paper explores the role of epigenetics in mental health disorders, focusing on the impact of environmental factors on gene expression. By examining the complex interplay between nature and nurture, the study provides insights into the influence of epigenetic modifications on psychiatric conditions such as schizophrenia, bipolar disorder, and post-traumatic stress disorder (PTSD). We performed semi-structured interviews with a broad range of psychiatric, genetic, and epigenetic specialists. In order to find pertinent studies looking at how epigenetic changes affect psychiatric diseases, including schizophrenia, bipolar disorder, and PTSD, a systematic literature analysis was carried out. Additionally, the paper discusses the potential implications of epigenetic research for personalized treatment approaches and early intervention strategies. Through a comprehensive literature review and qualitative analysis of expert interviews, this study enhances our understanding of the intricate relationship between epigenetics and mental health.\",\"PeriodicalId\":90556,\"journal\":{\"name\":\"International neuropsychiatric disease journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International neuropsychiatric disease journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9734/indj/2023/v20i2391\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International neuropsychiatric disease journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/indj/2023/v20i2391","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

精神疾病有多方面的起源,涉及基因和环境因素的结合,这些因素对其发展有重大贡献。近年来,研究人员强调表观遗传学机制的作用,认为它是环境因素如何影响生物过程的潜在分子基础。因此,表观遗传学作为理解这些复杂联系的一种手段,在精神病学领域越来越突出。这篇定性研究论文探讨了表观遗传学在心理健康障碍中的作用,重点是环境因素对基因表达的影响。通过研究先天和后天之间复杂的相互作用,该研究深入了解了表观遗传学修饰对精神分裂症、双相情感障碍和创伤后应激障碍(PTSD)等精神疾病的影响。我们对广泛的精神病学、遗传学和表观遗传学专家进行了半结构化访谈。为了找到表观遗传学变化如何影响精神疾病的相关研究,包括精神分裂症、双相情感障碍和创伤后应激障碍,进行了系统的文献分析。此外,本文还讨论了表观遗传学研究对个性化治疗方法和早期干预策略的潜在影响。通过全面的文献综述和专家访谈的定性分析,本研究增强了我们对表观遗传学与心理健康之间复杂关系的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
From Environment to Gene Expression: Epigenetics and the Development of Mental Health Disorders
Psychiatric disorders have multifaceted origins, involving a combination of genetic and environmental factors that contribute significantly to their development. In recent times, researchers have emphasized the role of epigenetic mechanisms as the underlying molecular foundation for how environmental factors influence biological processes. Consequently, the field of epigenetics has gained growing prominence within the realm of psychiatry as a means to understand these intricate connections. This qualitative research paper explores the role of epigenetics in mental health disorders, focusing on the impact of environmental factors on gene expression. By examining the complex interplay between nature and nurture, the study provides insights into the influence of epigenetic modifications on psychiatric conditions such as schizophrenia, bipolar disorder, and post-traumatic stress disorder (PTSD). We performed semi-structured interviews with a broad range of psychiatric, genetic, and epigenetic specialists. In order to find pertinent studies looking at how epigenetic changes affect psychiatric diseases, including schizophrenia, bipolar disorder, and PTSD, a systematic literature analysis was carried out. Additionally, the paper discusses the potential implications of epigenetic research for personalized treatment approaches and early intervention strategies. Through a comprehensive literature review and qualitative analysis of expert interviews, this study enhances our understanding of the intricate relationship between epigenetics and mental health.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Caffeine, Nicotine and Mdma Effects on the Brain Hippocampal Formation of Juvenile Experiential Models Barriers and Attitudes towards Mental Health Services in Nigeria: A Systematic Review Pathological Grief in Geriatric Age Group Affected by COVID-19 Deaths: A Community-Based Study The Main Risks of Fetal Alcohol Syndrome: An Integrative Review The Indiscriminate Use of Pesticides could Increase the Prevalence of Alzheimer's Disease? A Systematic Review
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1