减少绝经后出血妇女不确定子宫内膜活检数量的结构化评估

IF 1.6 Q4 ONCOLOGY International Journal of Surgical Oncology Pub Date : 2016-03-13 DOI:10.1155/2016/3039261
M. Breijer, N. Visser, N. van Hanegem, A. V. D. van der Wurff, B. Opmeer, H. V. van Doorn, B. Mol, J. Pijnenborg, A. Timmermans
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引用次数: 8

摘要

目标。确定门诊子宫内膜活检的结构化评估是否减少了不确定样本的数量。设计。回顾性队列研究。设置。单一医院病理实验室。人口。66例绝经后出血妇女的子宫内膜活检样本,在常规诊断检查中收集,评估为不足以进行可靠的组织学诊断。方法。要求病理实验室提供子宫内膜活检样本。检索到的样本由一位专门从事妇科的病理学家系统地重新评估。主要结果测量。有组织的重新评估后,初步评估与结论不一致。结果。我们从六个不同的病理实验室提取了66个子宫内膜活检样本中的36个。由一名专门从事妇科的病理学家对检索到的样本进行结构化重新评估,36个样本中有35个样本的结论没有改变。剩余样本含有大量子宫内膜组织,重新评估诊断为子宫内膜增生,无异型性。所有其他样本所含的材料不足以作出可靠的诊断。结论。对子宫内膜活检样本的结构化重新评估,由于材料不足被归类为不确定,并没有改变结论。虽然对病理学家来说,子宫内膜活检样本是否充足和/或不充足的诊断标准可能是有帮助的,但效率的提高可能很小。
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A Structured Assessment to Decrease the Amount of Inconclusive Endometrial Biopsies in Women with Postmenopausal Bleeding
Objective. To determine whether structured assessment of outpatient endometrial biopsies decreases the number of inconclusive samples. Design. Retrospective cohort study. Setting. Single hospital pathology laboratory. Population. Endometrial biopsy samples of 66 women with postmenopausal bleeding, collected during the usual diagnostic work-up and assessed as insufficient for a reliable histological diagnosis. Methods. Endometrial biopsy samples were requested from the pathology laboratories. The retrieved samples were systematically reassessed by a single pathologist specialized in gynecology. Main Outcome Measure. Disagreement between initial assessment and conclusion after structured reassessment. Results. We retrieved 36 of 66 endometrial biopsy samples from six different pathology laboratories. Structured reassessment of the retrieved samples by a single pathologist specialized in gynecology did not change the conclusion in 35 of the 36 samples. The remaining sample contained a large amount of endometrial tissue and the diagnosis at reassessment was endometrial hyperplasia without atypia. All other samples contained insufficient material for a reliable diagnosis. Conclusion. A structured reassessment of endometrial biopsies samples, which were classified as inconclusive due to insufficient material, did not change the conclusion. Although it might be helpful for pathologists to have diagnostic criteria for adequacy and/or inadequacy of an endometrial biopsy sample, the gain in efficiency is likely to be small.
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
期刊最新文献
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