COVID-19疫苗接种效果评估

E. Stoczyńska-Fidelus, P. Rieske
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引用次数: 0

摘要

Y: COVID-19疫苗非常有效。疫苗的体外研究表明,疫苗显示出所有预期的效果。疫苗可诱导细胞毒性淋巴细胞反应和体液反应。在真实条件下的研究表明,对传播的保护迅速减弱,对死亡和住院的保护非常好。应更好地分析康复者与接种者之间的差异。如果没有诊断测试显示出非常好的诊断敏感性和特异性,就不可能确定疫苗接种有效性的水平。诊断分析和流行病学分析证明,迅速引进疫苗的机制已经建立。然而,为下一次大流行做准备时,应考虑到COVID-19暴露的各种缺点。应该考虑研制冠状病毒通用疫苗。在开发出针对性疫苗之前,即使保护风险群体免于住院的有效性为25%,防止死亡的有效性为50%,也将证明非常有帮助。
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Assessment of COVID-19 vaccination effectiveness
Y The COVID-19 vaccines are very effective. In vitro studies of the vaccines indicate that the vaccines show all the expected effects. Vaccines induce both a cytotoxic lymphocyte response and a humoral response. Research under real conditions shows a rapidly weakening protection against transmission, and a very good protection against death and hospitalization. The differences between the convalescent and the vaccinated should be better analyzed. Determining the level of vaccination effectiveness would not be possible without diagnostic tests showing very good diagnostic sensitivity and specificity. Diagnostic analysis and epidemical analysis proved that mechanisms for the rapid introduction of vaccines have been accomplished. Nevertheless, preparations for the next pandemic should take into account the various shortcomings revealed by COVID-19. One should consider the preparation of universal coronavirus vaccines. Even 25% effectiveness in protecting risk groups from hospitalization, and 50% from death, will prove very helpful before targeted vaccines are developed.
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来源期刊
自引率
50.00%
发文量
18
期刊介绍: Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.
期刊最新文献
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