{"title":"基因组编辑工具修饰免疫细胞","authors":"E. Stoczyńska-Fidelus, P. Rieske","doi":"10.5114/pja.2021.111800","DOIUrl":null,"url":null,"abstract":"szczególną rolę. abSTracT Techniques such as TALEN, CRISPR-CAS9 or traktuje komórkę oraz jej elementy, np. białka, w sposób podobny do tego, którego używa się przy opracowywaniu układów scalonych w elektronice. PE polega na działaniu dwóch chimer, każdej złożonej z trzech podjednostek. Trzy elementy białkowe tworzą jedną chimerę (nikaza, odwrotna editing systems in therapy. Immune system cells also seem to be particularly suitable as starting points for the creation of completely new cell types thanks to synthetic biology, in which genome editing techniques play an important role. All this makes CRISPR-CAS9 or PE more and more interesting for immunologists. The article discusses the basics of these techniques and explains the reasons for their imperfections.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Genome editing tools to modify immune cells\",\"authors\":\"E. Stoczyńska-Fidelus, P. Rieske\",\"doi\":\"10.5114/pja.2021.111800\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"szczególną rolę. abSTracT Techniques such as TALEN, CRISPR-CAS9 or traktuje komórkę oraz jej elementy, np. białka, w sposób podobny do tego, którego używa się przy opracowywaniu układów scalonych w elektronice. PE polega na działaniu dwóch chimer, każdej złożonej z trzech podjednostek. Trzy elementy białkowe tworzą jedną chimerę (nikaza, odwrotna editing systems in therapy. Immune system cells also seem to be particularly suitable as starting points for the creation of completely new cell types thanks to synthetic biology, in which genome editing techniques play an important role. All this makes CRISPR-CAS9 or PE more and more interesting for immunologists. The article discusses the basics of these techniques and explains the reasons for their imperfections.\",\"PeriodicalId\":7469,\"journal\":{\"name\":\"Alergologia Polska - Polish Journal of Allergology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alergologia Polska - Polish Journal of Allergology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/pja.2021.111800\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alergologia Polska - Polish Journal of Allergology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/pja.2021.111800","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ALLERGY","Score":null,"Total":0}
szczególną rolę. abSTracT Techniques such as TALEN, CRISPR-CAS9 or traktuje komórkę oraz jej elementy, np. białka, w sposób podobny do tego, którego używa się przy opracowywaniu układów scalonych w elektronice. PE polega na działaniu dwóch chimer, każdej złożonej z trzech podjednostek. Trzy elementy białkowe tworzą jedną chimerę (nikaza, odwrotna editing systems in therapy. Immune system cells also seem to be particularly suitable as starting points for the creation of completely new cell types thanks to synthetic biology, in which genome editing techniques play an important role. All this makes CRISPR-CAS9 or PE more and more interesting for immunologists. The article discusses the basics of these techniques and explains the reasons for their imperfections.
期刊介绍：
Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.
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