重度哮喘的生物治疗——波兰过敏症学会和波兰呼吸疾病学会的立场

IF 0.2 Q4 ALLERGY Alergologia Polska - Polish Journal of Allergology Pub Date : 2023-01-01 DOI:10.5114/pja.2023.129093

B. Rogala, M. Kupczyk, G. Bochenek, P. Śliwiński, M. Moniuszko, P. Kuna, J. Glück, R. Dobek, M. Kulus, A. Kucharczyk, M. Chałubiński

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摘要

生物疗法在治疗包括哮喘在内的许多疾病方面取得了突破性进展。本文介绍了有关哮喘免疫病理生理学的知识状况，证明生物药物的使用是合理的，其机制的本质是对决定疾病表型表现的生物活性蛋白的抑制作用。证明生物治疗安全性和有效性的数据及前景

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Biological therapy of severe asthma – Position of Polish Society of Allergology and Polish Society of Respiratory Diseases

Biological therapy represents a breakthrough advance in the treatment of many diseases, including asthma. This article presents the state of knowledge concerning the immunopathophysiology of asthma justifying the use of biological drugs, the essence of whose mechanism is a suppressive effect on biologically active proteins determining the phenotypic manifestation of the disease. Data demonstrating the safety and efficacy of bio logical therapy and the prospects

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来源期刊

Alergologia Polska - Polish Journal of Allergology ALLERGY-

自引率

50.00%

发文量

期刊介绍： Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.