微胶囊剂型概述

Paroma Arefin, Md Shehan Habib, D. Chakraborty, S. Bhattacharjee, Suman Das, Debabrata Karmakar, D. Bhowmik
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引用次数: 6

摘要

与传统剂型相比,微胶囊在药物输送方面提供了多种便利。它是许多药物的独特载体系统。微胶囊化是一个有潜力的方法,可以显著延长药物的疗效,提高患者的依从性。该方法可减轻剂量倾倒的局限性、多次给药不便、肾脏疾病。这种剂型对需要服用多种药物的老年人有潜在的优势。但微胶囊的制备需要优化方法和配方,并进行适当的表征。本文综述了微胶囊和微球的优缺点。我们重点介绍了微胶囊和微球在制药工业中的应用。我们还讨论了微胶囊的表征过程。微胶囊开启了个体化、靶向给药的时代,副作用最小,更方便。关键词:微胶囊,微球,微胶囊,微球表征,微球应用
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An overview of microcapsule dosage form
Microcapsules offer a wide variety of convenience in drug delivery when compared with conventional dosage forms. It is a unique carrier system for many pharmaceuticals. Microencapsulation is a potential process which prolongs the efficacy of drug significantly and improves patient compliance. This approach can alleviate the limitations of dose dumping, multiple dose inconvenience, kidney disease. This dosage form has potential advantages for elderly people who have to take multiple drugs. But microcapsule preparation needs method and formulation optimization and proper characterization. In this review paper, we have discussed the advantages, limitation of the microcapsules and microspheres. We have highlighted the applications of microcapsules and microspheres in the pharmaceutical industries. We also discussed the characterization process of microcapsules. Microcapsules open the era of individualized, targeted drug delivery with minimal side effects and greater convenience. Keywords: Microencapsulation, Microspheres, Microcapsules, Characterization of microspheres, Application of microspheres.
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