人胎儿胸腺产生不变的效应γδ T细胞

The Tokushima journal of experimental medicine Pub Date : 2019-12-05 DOI:10.1084/jem.20190580

Paola Tieppo, M. Papadopoulou, Deborah Gatti, N. McGovern, J. Chan, F. Gosselin, Glenn Goetgeluk, K. Weening, Ling Ma, N. Dauby, Alexandra Cogan, C. Donner, F. Ginhoux, B. Vandekerckhove, D. Vermijlen

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引用次数: 54

摘要

Tieppo等人表明，人类胎儿胸腺产生具有程序化效应功能的不变γδ T细胞。这是由于高表达rna结合蛋白Lin28b引起的胎儿造血干细胞的固有特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The human fetal thymus generates invariant effector γδ T cells

Tieppo et al. show that the human fetal thymus generates invariant γδ T cells with programmed effector functions. This is due to an intrinsic property of fetal HSPCs caused by high expression of the RNA-binding protein Lin28b.

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The Tokushima journal of experimental medicine

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