医用粘土的分类与系统

A. Bondarev, E. Zhilyakova, N. Bondareva, D. Fadeeva
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引用次数: 2

摘要

本工作的目的是建立医用粘土的分类和系统。任务:对俄罗斯及周边国家医用粘土医药市场进行筛选营销研究;根据医用粘土的特点,对其进行分类和系统分类。资料有电子资源图书馆、俄罗斯药品注册、本人研究成果等。方法是分析和分类。结果。对医用粘土制药市场进行了筛选营销研究。确定了目前在俄罗斯有一种药用粘土“蒙脱石二面体”;以双八面体蒙脱石为基料的药品共有8种,其中国产药品3种,法国1种,美国1种,中国2种。医学粘土的分类和系统已经发展起来,根据医学粘土分为三大类,确定了它们的吸附特性:坡缕石、蒙脱石和高岭石粘土。医用粘土主要矿物的原子结构由八面体和硅氧四面体两个单元组成。由蒙脱石和高岭石矿物组成的医用粘土具有两种类型的孔隙;由蒙脱石和坡长石矿物组成的粘土比表面积较大;蒙脱石矿物的阳离子交换能力较高。结论。医学粘土的分类和系统已经发展起来,根据医学粘土分为三大类,确定了它们的吸附特性:坡缕石、蒙脱石和高岭石粘土。
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Classification and Systematics of Medical Clay
—The aim of the work is to develop classification and systematics of Medical Clays. Tasks: to conduct screening marketing study of the pharmaceutical market of medical clays in Russia and neighboring countries; to develop classification and systematics of Medical Clays with their characteristics. The materials are electronic resources eLIBRARY, Russian Drug Register, own research results also. The methods are analysis and classification. Results. Conducted a screening marketing study of the pharmaceutical market of Medical Clays. It was established that at present in Russia there is one pharmaceutical substance of Medical Clay “Smectite Dioctahedral”; 8 drugs based on Dioctahedral Smectite are registered: 3 of them are made on the basis of domestic substances, 1 - made in France, 1 - made in the USA, 2 - made in China. The classification and systematics of Medical Clays has been developed, according to which Medical Clays are represented by three groups that determine their sorption properties: Palygorskite, Smectite and Kaolinite Clays. The atomic structure of the main minerals of Medical Clays is composed of two units: octahedral and Silicon-Oxygen tetrahedral. Medical Clays consisting of Montmorillonite and Kaolinite minerals have two types of pores; the specific surface area is higher for clays consisting of Montmorillonite and Palygorskite minerals; the cation exchange capacity is higher for the Montmorillonite mineral. Conclusion. The classification and systematics of Medical Clays has been developed, according to which Medical Clays are represented by three groups that determine their sorption properties: Palygorskite, Smectite and Kaolinite Clays.
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