COMPARATIVE ASSESSMENT OF THE SENSITIVITY OF CAUSES OF WOUND INFECTIONS TO TOPICAL ANTIBACTERIAL DRUGS

The problems of treating victims with gunshot wounds are determined by the issue of prevention and treatment of purulent complications, because wounds received during hostilities are a priori infected, and the most dangerous complication of wounds is the development of purulent infection. The purpose of the research is to study the peculiarities of the microbial landscape of combat wounds and the antimicrobial activity of certain drugs in relation to extensively resistant and polyresistant microbial agents in order to develop algorithms in external therapy within the framework of complex treatment of these injuries Materials and methods. The data of microbiological studies of 32 victims with gunshot wounds were used in the work. Research results: Based on the results of monitoring the causative agents of purulent-inflammatory complications of wound injuries, a range of leading types of microorganisms was established: K. pneumoniae E. faecalis, S. haemolyticus, P. aeruginosa, E. coli. The isolation of flora resistant to most antibiotics from wounds dictates the need to change the strategy of infection control with strengthening measures to prevent nosocomial transmission and should be taken into account in the process of prescribing antibiotic therapy. Conclusion. The obtained results of the pilot study demonstrate the microbiological effectiveness of dioxidin, partially mupirocin and fusidin, which can be used in the complex treatment of microbial complications of wound injuries and the development of optimal tactics for providing medical care and treatment of the wounded, and can also serve as a basis for the development of a method of complex treatment for certain phases wound process, which allow simultaneous influence on several factors of pathogenesis.