自主性在无意识睡眠状态下起作用吗?

M. Nakao, A. Karashima, N. Katayama
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引用次数: 0

摘要

传统上,睡眠被理解为人类和动物在身体和生理上得到休息的一种无意识状态。然而,睡眠也被认为有助于大脑高级功能的发展和维持。实际上,睡眠状态下神经元的活动表现出特殊的动态,有些神经元在睡眠时比清醒时更加活跃。与神经元活动有关的分子和细胞机制被发现参与睡眠的功能。考虑到睡眠中的无意识,表征睡眠的神经生物学事件似乎是自主调节的。但是,真的是这样吗?本文就睡眠中的神经生物学现象及其对睡眠功能的影响作一综述。此外,还研究了无意识睡眠状态下的这些神经生物学事件是否受到因果调节。
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Is autonomy working under unconscious state of sleep?
Conventionally sleep is understood as an unconscious state in which human and animals are taking rest physically as well as physiologically. However, sleep has been suggested to serve for development and maintenance of the higher-order brain functions as well. Actually neuronal activities show peculiar dynamics to sleep state and some neurons become rather active during sleep than wakefulness. Associated with neuronal activities, molecular and cellular machinery are found to be involved for the functions of sleep. Considering unconsciousness during sleep, neurobiological events characterizing sleep seem to be autonomously regulated. But, are they? In this essay, the neurobiological phenomena during sleep and their possible contribution to the sleep functions are reviewed. In addition, it is examined whether these neurobiological events during unconscious state of sleep are causally regulated or not.
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