Q4 Medicine Duzce Medical Journal Pub Date : 2021-08-31 DOI:10.47493/ABANTMEDJ.860822
Ferhat Bingöl, Ihsan Solmaz, Orhan Ayyildiz
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引用次数: 0

摘要

2例(4%)患者yaak kalıtsal为杂合子。2例(4%)患者狼疮抗凝血药水平高,1例(2%)患者纤维蛋白原水平高。5例(10%)患者检测到PAI-1 (4G / 5G)基因多态性。31例(62%)确诊患者同时发现遗传和获得性危险因素。6例(12%)患者未发现遗传或获得性危险因素。讨论与结论:40岁以下成人非典型血栓形成和典型血栓形成是一种复杂的病理疾病,遗传和获得性病因危险因素可以共同确定。据观察,骨髓增殖性疾病应作为腹部血栓形成的一个病因进行评估,在存在潜在遗传风险因素的情况下,妇女使用口服避孕药(OCS)会增加血栓形成的风险。发现女性因妊娠、产褥期、使用OCS等原因血栓形成较多。
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Atipik Yerleşimli Trombozlar ile 40 Yaş Altı Erişkin Hastalardaki Tipik Yerleşimli Trombozlarda Etyolojik Faktörler.
yaş kalıtsal heterozygous in 2 (4%) patients. The lupus anticoagulant was found to be high in 2 (4%) patients, and the fibrinogen level in 1 (2%) patient. PAI-1 (4G / 5G) gene polymorphism was detected in 5 (10%) patients. Hereditary and acquired risk factors were found together in 31 (62%) of the patients diagnosed. No hereditary or acquired risk factor was found in 6 (12%) of the patients. DISCUSSION and CONCLUSION : Atypical thrombosis and typical thrombosis seen in adults under 40 years of age is a complex pathological disease in which hereditary and acquired etiological risk factors can be determined together. It was observed that myeloproliferative diseases should be evaluated as an etiological factor in abdominal thrombosis and oral contraceptives (OCS) use in women increases the risk of thrombosis in the presence of underlying hereditary risk factors. It was found that female gender had more thrombosis due to reasons such as pregnancy, puerperium, and OCS use.
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来源期刊
Duzce Medical Journal
Duzce Medical Journal Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
59
审稿时长
12 weeks
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