A. Etzerodt, Kyriaki Tsalkitzi, M. Maniecki, W. Damsky, Marcello Delfini, E. Baudoin, Morgane Moulin, M. Bosenberg, J. Graversen, N. Auphan-Anezin, S. Moestrup, T. Lawrence
{"title":"特异性靶向CD163+ tam可调动炎症单核细胞，促进T细胞介导的肿瘤消退","authors":"A. Etzerodt, Kyriaki Tsalkitzi, M. Maniecki, W. Damsky, Marcello Delfini, E. Baudoin, Morgane Moulin, M. Bosenberg, J. Graversen, N. Auphan-Anezin, S. Moestrup, T. Lawrence","doi":"10.1084/jem.20182124","DOIUrl":null,"url":null,"abstract":"Etzerodt et al. show that the specific targeting of CD163+ macrophages in melanoma drives inflammatory monocyte influx and promotes antitumor immunity, illustrating the importance of selective targeting of tumor-associated myeloid cells for achieving optimal therapeutic responses.","PeriodicalId":23015,"journal":{"name":"The Tokushima journal of experimental medicine","volume":"20 1","pages":"2394 - 2411"},"PeriodicalIF":0.0000,"publicationDate":"2019-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"131","resultStr":"{\"title\":\"Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell–mediated tumor regression\",\"authors\":\"A. Etzerodt, Kyriaki Tsalkitzi, M. Maniecki, W. Damsky, Marcello Delfini, E. Baudoin, Morgane Moulin, M. Bosenberg, J. Graversen, N. Auphan-Anezin, S. Moestrup, T. Lawrence\",\"doi\":\"10.1084/jem.20182124\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Etzerodt et al. show that the specific targeting of CD163+ macrophages in melanoma drives inflammatory monocyte influx and promotes antitumor immunity, illustrating the importance of selective targeting of tumor-associated myeloid cells for achieving optimal therapeutic responses.\",\"PeriodicalId\":23015,\"journal\":{\"name\":\"The Tokushima journal of experimental medicine\",\"volume\":\"20 1\",\"pages\":\"2394 - 2411\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"131\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Tokushima journal of experimental medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1084/jem.20182124\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Tokushima journal of experimental medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1084/jem.20182124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell–mediated tumor regression
Etzerodt et al. show that the specific targeting of CD163+ macrophages in melanoma drives inflammatory monocyte influx and promotes antitumor immunity, illustrating the importance of selective targeting of tumor-associated myeloid cells for achieving optimal therapeutic responses.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
