一例Graves病和甲状腺相关眼病患者在泗水Soetomo综合学术医院接受放射性碘治疗

Rizki Adrian Hakim, Stepanus Massora, Delfitri Lutfi, Hermina Novida
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引用次数: 1

摘要

Graves病(GD)是甲状腺毒症最常见的病因,其次是中毒性多结节性甲状腺肿和中毒性腺瘤。GD可通过抗甲状腺药物(ATDs)、手术或放射性碘(RAI)治疗。甲状腺相关眼病(TAO)或Graves眼病(GO)影响25%-50%的GD患者,其存在通常劝阻临床医生使用RAI治疗甲状腺功能亢进。氧化石墨烯的存在是GD患者使用RAI的相对禁忌症,因为RAI可使现有的氧化石墨烯恶化。可给予此类患者皮质类固醇预防,以减少GO恶化的可能性。然而,目前建议中度至重度活动性GO患者不要接受RAI。已建立的指南建议在这些患者中使用皮质类固醇预防。我们报告了一位GD和眼病患者,他接受了RAI治疗,并给予类固醇预防以防止GO恶化。
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A Patient With Graves’ Disease And Thyroid-Associated Orbitopathy Undergoing Radioactive Iodine in Dr. Soetomo General Academic Hospital, Surabaya
Graves’ Disease (GD) is the most common etiology of thyrotoxicosis, followed by toxic multinodular goiter and toxic adenoma. GD can be managed with anti-thyroid drugs (ATDs), surgery, or radioactive iodine (RAI). Thyroid-associated orbitopathy (TAO) or Graves’ Ophthalmopathy (GO) affects 25%-50% patients with GD, and its presence usually dissuade clinicians to use RAI in treating hyperthyroidism. The presence of GO is a relative contraindication use of RAI in patients with GD, as RAI can worsen existing GO. Corticosteroid prophylaxis can be given to such patients to reduce likelihood of worsening of GO. However, patient with moderate to severe active GO is currently advised against undergoing RAI. Established guidelines recommend the use of corticosteroid prophylaxis in these patients. We reported a patients with GD and orbitopathy who was treated with RAI and was given steroid prophylaxis to prevent worsening of GO.
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