加拿大儿童多系统炎症综合征。

Meghan Laverty, M. Salvadori, S. Squires, M. Ahmed, Lisa Eisenbeis, Santina J Lee, Annick Des Cormiers, Y. A. Li
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引用次数: 4

摘要

本文概述了加拿大各省和地区卫生当局报告的儿童多系统炎症综合征(MIS-C)病例的流行病学。儿童多系统炎症综合征是冠状病毒病2019 (COVID-19)后暂时出现的病毒后炎症综合征。症状可能包括发烧、腹痛、呕吐、腹泻、皮疹和其他炎症迹象。在加拿大,misc很罕见,在2020年3月11日至2021年10月2日期间,向加拿大公共卫生署报告了269例病例。这些病例中有142例(53%)是实验室确诊的COVID-19病例或与COVID-19病例有流行病学关联。病例报告的婴儿小至一周,大至18岁,中位年龄为6岁。男性比女性更容易发生病例(分别为58%对42%;p = 0.006)。几乎所有MIS-C病例(99%)需要住院治疗,36%需要入住重症监护病房。到目前为止没有死亡报告。MIS-C的时间趋势与报告的儿童COVID-19发病率时间趋势一致,存在2至6周的滞后。
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Multisystem inflammatory syndrome in children in Canada.
This article provides a summary of the epidemiology of multisystem inflammatory syndrome in children (MIS-C) cases reported nationally in Canada by provincial and territorial health authorities. Multisystem inflammatory syndrome in children is a post-viral inflammatory syndrome that temporally follows coronavirus disease 2019 (COVID-19). Symptoms may include fever, abdominal pain, vomiting, diarrhea, skin rash and other signs of inflammation. In Canada, MIS-C is rare, with 269 cases reported to the Public Health Agency of Canada between March 11, 2020 and October 2, 2021. One hundred forty-two (53%) of these cases were lab-confirmed COVID-19 cases or epidemiologically-linked with COVID-19 cases. Cases have been reported in infants as young as one week to youth as old as 18 years, with a median age of six years. Cases were more likely to occur in males than females (58% vs 42%, respectively; p=0.006). Almost all MIS-C cases (99%) required hospitalization and 36% required intensive care unit admission. No deaths have been reported to date. The time trend of MIS-C aligns with the incidence rate time trend of COVID-19 reported in children, with a two to six-week lag.
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