SYNTHESIS AND GROWTH-STIMULATING ACTIVITY OF TRIMECAINE ETHYL IODOETHANOATE

Novel activation methods such as ultrasonic activation and microwave irradiation are becoming increasingly popular in the green synthesis of ionic liquids and ionic compounds. The use of ionic liquids and ionic compounds is becoming more and more interesting for scientists precisely because of their growth-stimulating activity.The purpose.Synthesisof trimecaine ethyl iodoethanoatewascarried out via N-alkylation in classical conditions and using ultrasonicirradiation and microwave-assisted synthesis. Methodology.Thestructure and functional groups of novel synthesized substanceidentifiedby1H,13C NMRandIR,and growth-stimulating activity tested fortengenotypes of sweet sorghum seeds.Thesynthesis of trimecaine ethyliodoethanoate was carried out via N-alkylation in classical conditions and using microwave radiation and ultrasonic activation. Results.The synthesized ionic compoundswere characterized by IR, 1H and 13C NMR, growth-stimulating activity was tested on ten varieties and hybrids of sweet sorghum seeds. Alternative methods for the synthesis of ultrasonic and MW activation showed a good result in the synthesis of N,N-diethyl-N-ethylethanoate-N-(2-(mesitylamino)-2-oxoethyl)aminium iodide with a higher isolation yield in a shorter time compared to classical conditions. Conclusion.The product with the highest yield is formed under MW irradiation in a short time, while under classical conditions the yield was lower, and the reaction time was longer. The synthesized ionic compound had a better effect on the energy and germination of all types of sweet sorghum seeds compared to the control.