日志文件来源和数据频率对基于日志文件的患者特异性质量保证准确性的影响。

IF 2.4 4区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Zeitschrift fur Medizinische Physik Pub Date : 2023-06-24 DOI:10.1016/j.zemedi.2023.05.006
Akbar Azzi, Gerd Heilemann, Dietmar Georg, Supriyanto Ardjo Pawiro, Terry Mart, Wolfgang Lechner
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引用次数: 0

摘要

为患者特异性质量保证(PSQA)进行幻像测量增加了适应性放疗程序的大量时间。可以使用基于日志文件的PSQA来提高此过程的效率。本研究比较了存储在肿瘤信息系统(OIS)中的高频直线加速器(Linac)日志文件和低频日志数据的剂量学准确性。30例患者最近在头颈部(HN),脑和前列腺区域接受了体积调制电弧治疗(VMAT),另外10例患者接受了立体定向体放射治疗(SBRT)和3d适形放疗(3D-CRT)技术。使用含有单一组分的测井数据来计算剂量分布。采用2%/2 mm标准和30%剂量阈值的伽马分析来评估Linac日志文件和OIS日志之间的剂量学差异。参照原治疗方案。此外,还报道了计划靶体积(PTV)的D98%、D50%和D2%的DVH参数,以及对几个危险器官(OARs)的剂量。两种log类型的剂量分布与原始剂量有显著差异,脑病例的PTV D98%和D2% (r 98% (r = 0.005)),前列腺病例的PTV D50% (r = 0.015)。两种原木类型在D50%方面无显著差异。OIS日志的叶片位置的均方根误差(RMS)大约是VMAT计划的Linac日志文件的均方根误差的两倍,但与3D-CRT计划相同。gamma通过率与RMS误差之间的关系显示,对于Linac日志文件(r = -0.58,p 对于RMS误差为90%)具有适度的相关性
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Impact of log file source and data frequency on accuracy of log file-based patient specific quality assurance.

Performing phantom measurements for patient-specific quality assurance (PSQA) adds a significant amount of time to the adaptive radiotherapy procedure. Log file based PSQA can be used to increase the efficiency of this process. This study compared the dosimetric accuracy of high-frequency linear accelerator (Linac) log files and low-frequency log data stored in the oncology information system (OIS). Thirty patients were included, that were recently treated in the head and neck (HN), brain, and prostate region with volumetric modulated arc therapy (VMAT) and an additional ten patients treated using stereotactic body radiation therapy (SBRT) with 3D-conformal radiotherapy (3D-CRT) technique. Log data containing a single fraction were used to calculate the dose distributions. The dosimetric differences between Linac log files and OIS logs were evaluated with a gamma analysis with 2%/2 mm criterion and dose threshold of 30%. The original treatment plan was used as a reference. Moreover, DVH parameters of D98%, D50%, and D2% of the planning-target volume (PTV) and dose to several organs at risk (OARs) were reported. Significant differences in dose distributions between the two log types and the original dose were observed for PTV D98% and D2% (r < 0.001) for HN cases, PTV D98% (r = 0.005) for brain cases, and PTV D50% (r = 0.015) for prostate cases. No significant differences were found between the two log types with respect to D50%. The root mean square (RMS) error of the leaf positions of the OIS log was approximately twice the RMS error of the Linac log file for VMAT plans, but identical for 3D-CRT plans. The relationship between the gamma pass rate and the RMS error showed a moderate correlation for the Linac log files (r = -0.58, p < 0.001) and strong correlation for OIS logs (r = -0.71, p < 0.001). Furthermore, all doses calculated using Linac log files and OIS log data had a GPR >90% for an RMS error < 3.3 mm. Based on these findings, a tolerance limit of RMS error of 3.3 mm for considering OIS log based PSQA was established. Nevertheless, the OIS log data quality should be improved to achieve adequate PSQA.

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来源期刊
CiteScore
3.70
自引率
10.00%
发文量
69
审稿时长
65 days
期刊介绍: Zeitschrift fur Medizinische Physik (Journal of Medical Physics) is an official organ of the German and Austrian Society of Medical Physic and the Swiss Society of Radiobiology and Medical Physics.The Journal is a platform for basic research and practical applications of physical procedures in medical diagnostics and therapy. The articles are reviewed following international standards of peer reviewing. Focuses of the articles are: -Biophysical methods in radiation therapy and nuclear medicine -Dosimetry and radiation protection -Radiological diagnostics and quality assurance -Modern imaging techniques, such as computed tomography, magnetic resonance imaging, positron emission tomography -Ultrasonography diagnostics, application of laser and UV rays -Electronic processing of biosignals -Artificial intelligence and machine learning in medical physics In the Journal, the latest scientific insights find their expression in the form of original articles, reviews, technical communications, and information for the clinical practice.
期刊最新文献
Editorial Board Contents Development and clinical implementation of a digital system for risk assessments for radiation therapy End-to-end testing for stereotactic radiotherapy including the development of a Multi-Modality phantom Note on uncertainty in Monte Carlo dose calculations and its relation to microdosimetry
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