Evaluation of left ventricular performance in aortic stenosis, aortic regurgitation and mitral regurgitation from the stroke work/left ventricular mass ratio.

European journal of cardiology Pub Date : 1979-10-01
A Nitenberg, J P Richalet, D Laurent
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Abstract

Evaluation of left ventricular performance in aortic stenosis, aortic regurgitation and mitral regurgitation from the stroke work/left ventricular mass ratio. Europ. J. Cardiol., 10/4, 279--294. 132 patients with a pure valvular dysfunction affecting a single orifice, namely aortic stenosis, aortic or mitral regurgitation, were studied. All patients, including 20 control subjects, underwent hemodynamic examination of both right and left heart chambers including left cineangiography. Using the stroke work index/myocardial mass ratio (SWI/MLV), for which the limits in normal subjects are narrow (0.81 +/- 0.03 . g-1) it was possible to divide these patients into three groups: Group I (SWI/MLV greater than 0.87 gm . g-1) characterized by a proportionately greater increase in stroke work index than myocardial mass (hyperfunctioning ventricle). Group II (0.87 gm . g-1 greater than or equal to SWI/MLV greater than or equal to 0.75 gm . g-1) characterized by a parallel increase in stroke work index and myocardial mass (normally functioning ventricle). Group III (SWI/MLV less than 0.75 gm . g-1) for which the increase in myocardial mass was proportionately greater than that of the stroke work index (hypofunctioning ventricle). As one progresses from group I to III, there is a concomitant fall in ventricular function with decreased mean velocity of circumferential fiber shortening (VCF), ejection fraction (EF) and increased enddiastolic volume (EDV) together with the hypertrophy of the left ventricle during the last stage. We conclude that the SWI/MLV ratio is an easy to calculate index, independent of the unerlying dysfunction, which evaluates left ventricular function by taking into account the myocardial mass.

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从卒中功/左心室质量比评价主动脉瓣狭窄、主动脉瓣反流和二尖瓣反流的左心室表现。
从卒中功/左心室质量比评价主动脉瓣狭窄、主动脉瓣反流和二尖瓣反流的左心室表现。四。j .心功能杂志。, 10/4, 279—294。研究了132例单纯瓣膜功能障碍患者,即主动脉瓣狭窄、主动脉瓣或二尖瓣反流。所有患者(包括20名对照组)均行左、右心室血流动力学检查,包括左心室血管造影。使用脑卒中功指数/心肌质量比(SWI/MLV),正常人的极限较窄(0.81 +/- 0.03)。g-1),可将患者分为三组:I组(SWI/MLV大于0.87 gm);G-1)的特点是卒中功指数比心肌质量(心室功能亢进)成比例地增加。II组(0.87 gm;g-1大于等于SWI/MLV大于等于0.75 gm。G-1)表现为卒中功指数和心肌质量(正常功能的心室)平行增加。第三组(SWI/MLV小于0.75 gm)。G-1),心肌质量的增加成比例地大于卒中工作指数(心室功能减退)的增加。随着患者从I组发展到III组,心室功能下降,周纤维缩短(VCF)平均速度下降,射血分数(EF)下降,舒张末期容积(EDV)增加,左心室肥大。我们得出结论,SWI/MLV比率是一个易于计算的指标,独立于潜在的功能障碍,它通过考虑心肌质量来评估左心室功能。
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