Changes in 86-rubidium uptake in erythrocytes of digoxin-treated patients, in heart failure with sinus rhythm. Relationship to clinical effects.

European journal of cardiology Pub Date : 1981-01-01
F Zannad, R J Royer, J Robert
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Abstract

Previous studies have shown a significant relationship between the clinical effect of digoxin and a tissue response, namely the inhibition of 86Rb uptake by the patients' erythrocytes. In the present study, this relationship is confirmed in patients, in heart failure with sinus rhythm. The slowing of the heart rate but not the QS2 index changes correlates significantly with the 86Rb uptake inhibition.

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心力衰竭伴窦性心律患者地高辛治疗后红细胞86-铷摄取的变化。与临床效果的关系。
既往研究表明地高辛的临床效果与组织反应(即患者红细胞对86Rb摄取的抑制)之间存在显著关系。在本研究中,这种关系在伴有窦性心律的心力衰竭患者中得到证实。心率减慢而非QS2指数改变与86Rb摄取抑制显著相关。
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Plasma pancreatic polypeptide and gastrin in the assessment of autonomic activity in acute myocardial infarction. Effects of intrinsic sympathetic activity of beta-blockers on SA and AV nodes in man. Coronary arterial stenosis and subclavian steal in Takayasu's arteritis. Changes in 86-rubidium uptake in erythrocytes of digoxin-treated patients, in heart failure with sinus rhythm. Relationship to clinical effects. Digoxin in the elderly and in renal failure. Contribution of erythrocyte 86-rubidium uptake tests.
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