A study on sensitivity, reproducibility, and stability of sourness and saltiness taste sensors using a mixture of lipid membranes

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology Biosensors and Bioelectronics: X Pub Date : 2024-03-13 DOI:10.1016/j.biosx.2024.100459
Rita Prasetyowati , Rizky Aflaha , Hanif Khoirudin , Moch. Rifqi Tamara , Roto Roto , Pekik Nurwantoro , Kuwat Triyana
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引用次数: 0

Abstract

Our study successfully fabricated sourness and saltiness sensors and investigated the response toward acetic acid and sodium chloride as the sourness and saltiness sample solutions, respectively. The sensors were made using a lipid membrane with a mixture of two materials. The fabricated sensors can detect the concentration of a small amount of 0.03 mM for the sourness sensor and 0.316 mM for the saltiness sensor, much lower than the human tongue threshold. Moreover, the sensors show a directly proportional response for both sourness and saltiness sensors in the range of 0.03–3 mM of acetic acid and 0.316–31.6 mM of sodium chloride, respectively. The interaction between positive charge in the lipid membrane and anionic species in the sample solution was believed to be the sensing mechanism in this research. Both sensors were refabricated three times, and the saltiness sensor exhibited a similar response when exposed to 3.16 mM of sodium chloride, while the sourness sensor still has to improve its reproducibility. In addition, the fabricated sensors were also tested on three consecutive days to observe the stability.

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关于使用脂膜混合物的酸味和咸味传感器的灵敏度、再现性和稳定性的研究
我们的研究成功制作了酸味和咸味传感器,并研究了它们分别对醋酸和氯化钠作为酸味和咸味样品溶液的反应。传感器是用两种材料的混合物制成的脂质膜。制作出的传感器能检测到的酸味浓度和咸味浓度分别为 0.03 毫摩尔和 0.316 毫摩尔,远低于人类舌头的阈值。此外,在醋酸浓度为 0.03-3 毫摩尔和氯化钠浓度为 0.316-31.6 毫摩尔的范围内,酸味和咸味传感器都显示出直接的比例响应。在这项研究中,脂膜中的正电荷与样品溶液中的阴离子物质之间的相互作用被认为是传感机制。这两种传感器都被重新制作了三次,当暴露在 3.16 毫摩尔氯化钠溶液中时,咸味传感器表现出相似的响应,而酸味传感器的重现性仍有待提高。此外,还对制作好的传感器进行了连续三天的测试,以观察其稳定性。
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来源期刊
Biosensors and Bioelectronics: X
Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
4.60
自引率
0.00%
发文量
166
审稿时长
54 days
期刊介绍: Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.
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