Comparing two deep learning spectral reconstruction levels for abdominal evaluation using a rapid-kVp-switching dual-energy CT scanner

IF 2.2 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Abdominal Radiology Pub Date : 2025-03-17 DOI:10.1007/s00261-025-04868-1
Hakki Serdar Sagdic, Mohammadreza Hosseini-Siyanaki, Abheek Raviprasad, Sefat Munjerin, Daniella Fabri, Joseph Grajo, Victor Martins Tonso, Laura Magnelli, Daniela Hochhegger, Evelyn Anthony, Bruno Hochhegger, Reza Forghani
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Abstract

Purpose

Deep Learning Spectral Reconstruction (DLSR) potentially improves dual-energy CT (DECT) image quality, but there is a paucity of research involving human abdominal DECT scans. The purpose of this study was to comprehensively evaluate image quality by quantitatively and qualitatively comparing strong and standard levels of a DLSR algorithm. Optimal virtual monochromatic image (VMI) energy levels were also evaluated.

Methods

DECT scans of the abdomen/pelvis from 51 patients were retrospectively evaluated. VMIs were reconstructed at energy levels ranging from 35 to 200 keV using both standard and strong DLSR levels. For quantitative analysis, various abdominal structures were assessed using regions of interest, and mean signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) values were calculated. This was supplemented with a qualitative evaluation of VMIs reconstructed at 35, 45, 55, and 65 keV.

Results

The strong-level DLSR demonstrated significantly better SNR and CNR values (p < 0.0001) compared to standard-level DLSR across all structures. The optimal SNR was observed at 70 keV (p < 0.0001), while the optimal CNR was found at 65 keV (p < 0.0001). The average qualitative scores between standard and strong DLSR were significantly different at 45, 55, and 65 keV (p < 0.0001). There was a moderate level of agreement between observers (ICC = 0.427, p < 0.0001).

Conclusion

A DLSR set to a strong level significantly improves image quality compared to standard-level DLSR, potentially enhancing the diagnostic evaluation of abdominal DECT scans. In addition to achieving a very high SNR, 65 keV VMIs had the highest CNR, which differs from what is typically observed with traditional DECT using non-deep learning reconstruction approaches.

Graphical Abstract

Abstract Image

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比较两种用于腹部评估的深度学习光谱重建水平,使用快速kvp开关双能CT扫描仪。
目的:深度学习光谱重建(DLSR)可能提高双能CT (DECT)图像质量,但缺乏涉及人体腹部DECT扫描的研究。本研究的目的是通过定量和定性比较DLSR算法的强水平和标准水平来综合评价图像质量。并对最佳虚拟单色图像(VMI)能级进行了评价。方法:回顾性分析51例患者的腹部/骨盆DECT扫描。在35 ~ 200 keV的能级范围内,使用标准能级和强DLSR能级重建vmi。为了进行定量分析,使用感兴趣的区域评估各种腹部结构,并计算平均信噪比(SNR)和噪声对比比(CNR)值。在35、45、55和65 keV时重建VMIs进行定性评价。结论:与标准水平DLSR相比,强水平DLSR可显著改善图像质量,可能增强腹部DECT扫描的诊断评价。除了实现非常高的信噪比外,65 keV vmi具有最高的CNR,这与使用非深度学习重建方法的传统DECT通常观察到的结果不同。
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来源期刊
Abdominal Radiology
Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.20
自引率
8.30%
发文量
334
期刊介绍: Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits
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