A Novel Minimally Invasive Surgical Procedure for the Treatment of Steatocystoma Multiplex

IF 3.7 4区 医学 Q1 DERMATOLOGY Dermatologic Therapy Pub Date : 2025-03-24 DOI:10.1155/dth/8623135
Nan Zhang, Zepeng Li, Zhongke Xue, Weiling Wang, Yan Zheng, Wenwei Zhao
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Abstract

Background: Steatocystoma multiplex (SM) is an asymptomatic benign skin lesion, characterized by multiple sebum-containing dermal cysts.

Objectives: In this study, we report a novel surgical procedure of removal of the cysts followed by a 5-fluorouracil injection to fulfill the cosmetic needs of patients with SM.

Methods: From January 2023 to January 2024, 35 patients with SM, 2 of whom showed septic steatocystoma, were surgically treated with the novel surgical method in the First Affiliated Hospital of Xi’an Jiaotong University. All procedures were performed in the outpatient operating room. Patients were in close follow-up for postoperative data, with the most recent follow-up until March 2024.

Results: The surgical intervention is completed within a maximum duration of 40 min for each patient, and all 35 patients with SM exhibited complete postoperative wound healing with no relapse, no cicatrization, and limited hyperpigmentation in mere 4 patients (all within 3 months postoperatively), indicating a favorable overall cosmetic outcome at the latest follow-up in March 2024.

Conclusion: Surgical removal of the cysts with subsequent 5-fluorouracil injection is a promising and novel operative procedure for SM which is minimally invasive, fulfills the cosmetic needs of the patients, and leads to no recurrence in any case.

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背景:多发性脂肪囊肿(SM)是一种无症状的良性皮肤病变,其特征是多发性含皮脂的真皮囊肿。 研究目的在本研究中,我们报告了一种新颖的手术方法,即切除囊肿后注射 5-氟尿嘧啶,以满足多发性脂肪囊肿患者的美容需求。 手术方法自2023年1月至2024年1月,西安交通大学第一附属医院对35例SM患者进行了手术治疗,其中2例为化脓性脂肪囊肿。所有手术均在门诊手术室进行。对患者术后数据进行了密切随访,最近一次随访至2024年3月。 结果所有 35 例 SM 患者的术后伤口均完全愈合,无复发,无糜烂,仅有 4 例患者出现局限性色素沉着(均在术后 3 个月内),表明在 2024 年 3 月的最近一次随访中,总体美容效果良好。 结论手术切除囊肿,随后注射 5-氟尿嘧啶是治疗 SM 的一种很有前景的新型手术方法,它创伤小,满足了患者的美容需求,而且在任何情况下都不会复发。
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来源期刊
Dermatologic Therapy
Dermatologic Therapy 医学-皮肤病学
CiteScore
7.00
自引率
8.30%
发文量
711
审稿时长
3 months
期刊介绍: Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.
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