Right ventricular function at rest and during exercise in patients with coronary heart disease.

European journal of cardiology Pub Date : 1980-02-01
K R Karsch, S Scheufler, H Blanke, P Rentrop
{"title":"Right ventricular function at rest and during exercise in patients with coronary heart disease.","authors":"K R Karsch,&nbsp;S Scheufler,&nbsp;H Blanke,&nbsp;P Rentrop","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Biplane cineventriculograms of the right ventricle at rest and during exercise were made of 16 patients with a right coronary artery stenosis of greater than 50% and less than 90% to explain the alteration of the volumes and function of the right ventricle during exercise-induced angina pectoris. The right ventricular enddiastolic volume increases from 113 +/- 6.6 ml/m2 to 133.9 +/- 9.8 ml/m2 (P less than 0.001). The endsystolic volume increases from 48.9 +/- 4.1 ml/m2 to 52.9 +/- 5.3 ml/m2. The stroke volume index increases from 64 +/- 5.5 ml/m2 to 81 +/-8.3 ml/m2 (P less than 0.001). At the same time the ejection fraction increases from 56.5 +/- 2.9% to 60.2 +/- 3.2% (P less than 0.05). The left ventricular enddiastolic pressure increases from 12.8 +/- 1.5 mm Hg to 26.6 +/- 1.6 mm Hg (P less than 0.001). The enddiastolic pressure of the right ventricle increases from 5.8 +/- 0.5 to 12.2 +/- 0.8 mm Hg (P less than 0.001). The mean velocity of diameter shortening, VD, increases from 0.9 +/- 0.06 D/s to 1.12 +/- 0.09 D/s (P less than 0.05). Exercise-induced angina pectoris leads to a considerable increase of the left ventricular enddiastolic pressure and therefore to an increase of the right ventricular afterload. The increase of afterload in patients with a right coronary artery stenosis is compensated by a considerable increase of the enddiastolic volume: the pump-function during exercise-induced angina pectoris is maintained by an increase of preload.</p>","PeriodicalId":72971,"journal":{"name":"European journal of cardiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1980-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of cardiology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Biplane cineventriculograms of the right ventricle at rest and during exercise were made of 16 patients with a right coronary artery stenosis of greater than 50% and less than 90% to explain the alteration of the volumes and function of the right ventricle during exercise-induced angina pectoris. The right ventricular enddiastolic volume increases from 113 +/- 6.6 ml/m2 to 133.9 +/- 9.8 ml/m2 (P less than 0.001). The endsystolic volume increases from 48.9 +/- 4.1 ml/m2 to 52.9 +/- 5.3 ml/m2. The stroke volume index increases from 64 +/- 5.5 ml/m2 to 81 +/-8.3 ml/m2 (P less than 0.001). At the same time the ejection fraction increases from 56.5 +/- 2.9% to 60.2 +/- 3.2% (P less than 0.05). The left ventricular enddiastolic pressure increases from 12.8 +/- 1.5 mm Hg to 26.6 +/- 1.6 mm Hg (P less than 0.001). The enddiastolic pressure of the right ventricle increases from 5.8 +/- 0.5 to 12.2 +/- 0.8 mm Hg (P less than 0.001). The mean velocity of diameter shortening, VD, increases from 0.9 +/- 0.06 D/s to 1.12 +/- 0.09 D/s (P less than 0.05). Exercise-induced angina pectoris leads to a considerable increase of the left ventricular enddiastolic pressure and therefore to an increase of the right ventricular afterload. The increase of afterload in patients with a right coronary artery stenosis is compensated by a considerable increase of the enddiastolic volume: the pump-function during exercise-induced angina pectoris is maintained by an increase of preload.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
冠心病患者静息和运动时的右心室功能。
本文对16例右冠状动脉狭窄大于50%和小于90%的患者进行静息和运动时的右心室双平面影室图,以解释运动性心绞痛时右心室容量和功能的改变。右心室舒张末期容积从113 +/- 6.6 ml/m2增加到133.9 +/- 9.8 ml/m2 (P < 0.001)。收缩期容积从48.9 +/- 4.1 ml/m2增加到52.9 +/- 5.3 ml/m2。卒中容积指数从64 +/- 5.5 ml/m2增加到81 +/-8.3 ml/m2 (P < 0.001)。同时,射血分数由56.5 +/- 2.9%上升至60.2 +/- 3.2% (P < 0.05)。左室舒张压由12.8 +/- 1.5 mm Hg升高至26.6 +/- 1.6 mm Hg (P < 0.001)。右心室舒张压由5.8 +/- 0.5升高至12.2 +/- 0.8 mm Hg (P < 0.001)。平均直径缩短速度VD由0.9 +/- 0.06 D/s增加到1.12 +/- 0.09 D/s (P < 0.05)。运动性心绞痛导致左心室舒张压显著升高,从而导致右心室后负荷升高。右冠状动脉狭窄患者后负荷的增加可通过舒张期容积的显著增加得到补偿:运动诱发心绞痛时的泵功能是通过增加前负荷来维持的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Plasma pancreatic polypeptide and gastrin in the assessment of autonomic activity in acute myocardial infarction. Effects of intrinsic sympathetic activity of beta-blockers on SA and AV nodes in man. Coronary arterial stenosis and subclavian steal in Takayasu's arteritis. Changes in 86-rubidium uptake in erythrocytes of digoxin-treated patients, in heart failure with sinus rhythm. Relationship to clinical effects. Digoxin in the elderly and in renal failure. Contribution of erythrocyte 86-rubidium uptake tests.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1