Ovarian tumor diagnosed during pregnancy & their management

Harsha Khullar, G. Mediratta, S. Garg
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Abstract

The incidence of ovarian tumor in pregnancy is quite rare approximating to 1 in 190 pregnancies. Scanty evidence is available for the treatment of this condition due to lack of RCTs and cohort studies. However, only 1-6 % of ovarian tumors are reported to be malignant in nature during pregnancy. We report 6 cases of ovarian malignancies which depicts the difficulty of making this rare diagnosis along with their brief clinical presentation, diagnosis and therapeutic approach. The findings from these cases describe the interventions which ameliorates patients’ quality of life. *Correspondence to: Harsha Khullar, Vice-Chairperson& Senior Consultant, Institute of Obstetrics & Gynecology, Sir Ganga Ram Hospital, New Delhi, India, E-mail: harsha_khullar@yahoo.com Received: May 25, 2020; Accepted: June 16, 2020; Published: June 19, 2020 Key points • Ovarian tumor is the fifth most common cancer • Only 3 to 5% of ovarian tumors in pregnancy are malignant. • Signs and symptoms include incidental finding, abdominal or back pain. • High levels of Maternal Serum AFP, Inhibin A obtained during aneuploidy screening can be a sign of GCT • Adequate surgical staging is important for stage I cancer. • Ideal time for surgery is in second trimester of pregnancy • Treatment in each case should be individualized • Chemotherapy can be given antenatally but with prior consents.
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妊娠期诊断的卵巢肿瘤及其处理
妊娠期卵巢肿瘤的发生率非常罕见,约为1 / 190。由于缺乏随机对照试验和队列研究,治疗这种疾病的证据很少。然而,据报道,只有1- 6%的卵巢肿瘤在怀孕期间是恶性的。我们报告了6例卵巢恶性肿瘤,描述了这种罕见诊断的困难,以及它们的简短临床表现,诊断和治疗方法。这些病例的发现描述了改善患者生活质量的干预措施。*通讯对象:印度新德里Sir Ganga Ram医院妇产科研究所副主任兼高级顾问Harsha Khullar, E-mail: harsha_khullar@yahoo.com录用日期:2020年6月16日;•卵巢肿瘤是第五大常见癌症•妊娠期卵巢肿瘤中只有3%至5%是恶性的。•体征和症状包括意外发现,腹部或背部疼痛。•在非整倍体筛查中获得的高水平的母体血清AFP,抑制素A可能是GCT的征兆•对于I期癌症,适当的手术分期是重要的。•手术的理想时间是在妊娠中期•每种情况下的治疗应该是个体化的•化疗可以在产前进行,但必须事先征得同意。
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