{"title":"Ovarian tumor diagnosed during pregnancy & their management","authors":"Harsha Khullar, G. Mediratta, S. Garg","doi":"10.15761/icst.1000338","DOIUrl":null,"url":null,"abstract":"The incidence of ovarian tumor in pregnancy is quite rare approximating to 1 in 190 pregnancies. Scanty evidence is available for the treatment of this condition due to lack of RCTs and cohort studies. However, only 1-6 % of ovarian tumors are reported to be malignant in nature during pregnancy. We report 6 cases of ovarian malignancies which depicts the difficulty of making this rare diagnosis along with their brief clinical presentation, diagnosis and therapeutic approach. The findings from these cases describe the interventions which ameliorates patients’ quality of life. *Correspondence to: Harsha Khullar, Vice-Chairperson& Senior Consultant, Institute of Obstetrics & Gynecology, Sir Ganga Ram Hospital, New Delhi, India, E-mail: harsha_khullar@yahoo.com Received: May 25, 2020; Accepted: June 16, 2020; Published: June 19, 2020 Key points • Ovarian tumor is the fifth most common cancer • Only 3 to 5% of ovarian tumors in pregnancy are malignant. • Signs and symptoms include incidental finding, abdominal or back pain. • High levels of Maternal Serum AFP, Inhibin A obtained during aneuploidy screening can be a sign of GCT • Adequate surgical staging is important for stage I cancer. • Ideal time for surgery is in second trimester of pregnancy • Treatment in each case should be individualized • Chemotherapy can be given antenatally but with prior consents.","PeriodicalId":90850,"journal":{"name":"Integrative cancer science and therapeutics","volume":"7 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Integrative cancer science and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/icst.1000338","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The incidence of ovarian tumor in pregnancy is quite rare approximating to 1 in 190 pregnancies. Scanty evidence is available for the treatment of this condition due to lack of RCTs and cohort studies. However, only 1-6 % of ovarian tumors are reported to be malignant in nature during pregnancy. We report 6 cases of ovarian malignancies which depicts the difficulty of making this rare diagnosis along with their brief clinical presentation, diagnosis and therapeutic approach. The findings from these cases describe the interventions which ameliorates patients’ quality of life. *Correspondence to: Harsha Khullar, Vice-Chairperson& Senior Consultant, Institute of Obstetrics & Gynecology, Sir Ganga Ram Hospital, New Delhi, India, E-mail: harsha_khullar@yahoo.com Received: May 25, 2020; Accepted: June 16, 2020; Published: June 19, 2020 Key points • Ovarian tumor is the fifth most common cancer • Only 3 to 5% of ovarian tumors in pregnancy are malignant. • Signs and symptoms include incidental finding, abdominal or back pain. • High levels of Maternal Serum AFP, Inhibin A obtained during aneuploidy screening can be a sign of GCT • Adequate surgical staging is important for stage I cancer. • Ideal time for surgery is in second trimester of pregnancy • Treatment in each case should be individualized • Chemotherapy can be given antenatally but with prior consents.