Control of Blood Glucose in Type 2 Diabetes by Modification of Conventional Diet Composition

Abstract

In this study, 100 clinically diagnosed types 2 diabetic patients were selected for investigation. The objective of this study was to control of blood glucose level in type 2 diabetic patient by the modification of conventional diet composition. The patients were studied using a randomized 5 week crossover design with the conventional and modified conventional diet (test diet) respectively. The mean body weight, BMI, waist circumference and waist to hip ratio were 60.1 ± 2.21 kg, 24.1 ± 2.71 kg/meter², 36.2 ± 0.762 inch and 0.904 ± 0.029 respectively with the conventional diet, that decreased to 59.5 ± 2.20 kg (P<0.01), 23.9 ± 2.73 kg/ meter² (P<0.05), 33.7 ± 0.512 inch (P<0.05) and 0.897 ± 0.026 (P<0.05) respectively after intervention of the test diet. The mean systolic and diastolic blood pressure were 124 ± 11.4 and 82 ± 6.9 mmHg respectively and after 5 weeks of intervention of test diet both the blood pressure decreased significantly (P<0.05) to 112 ± 8.6 and 69± 6.9 mmHg respectively. The mean fasting and postprandial blood sugar were 10.4 ± 0.38 and 12 ± 0.53 mmol/l with the conventional diet whereas it decreased significantly (P <0.001) to 8.1 ± 0.75 and 9.8 ± 0.40 mmol/l respectively. Before starting the test diet, the mean HbA1C was 6.4 ± 0.13 % but 5 week of post feeding the HbA1C decreased to 5.8 ± 0.19 % ( P<0.001). The mean ALT value was 47.5 ± 8.95 u/l and decreased significantly (P < 0.05) to 24.5 ± 4.19 u/l. During conventional diet, the mean AST and ALP level were 55.8 ± 25.18 and 93 ± 6.06 u/l respectively, after intervention it decreased to 42.8 ± 27.43 and 75 ± 10.85 u/l but not significantly (P = 0.759, P= 0.337).