Antimicrobial Effect of Non-polar Compounds Extracted from Medicinal Plants

Sana Ghazanfar, M. Shahid, Hua-dong Liu, M. Shafa
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Abstract

The learning is too focussing on identification of compounds dependable for the antimicrobial. Medicinal plants have a significant wellspring of pharmacological impacts that goes about as new of diseases, anti-infections, antioxidant and hostile to malignancy operators. In this study, antimicrobial and antioxidant properties of thyme (Thymus vulgaris L.) black pepper (Piper nigrum L.) Cinnamon (Cinnamomum verum L.) green tea (Camellia sinensis L.) nutmegs (Myristicafragrans Houtt) were investigated. Medicinal plants are generally devoured around the world; green tea contains a lot of non-oxidized flavonoids, named catechins. Therapeutic plants are additionally proof that lessens oxidative pressure hostile to diabetic and switches endothelial brokenness. The examination was led to investigate the antimicrobial and cancer prevention agent properties. The antimicrobial activities were analyzed by disc diffusion test against chosen microbial strain. Anti-microbial activity of n-hexane extract from medicinal plants against two “Gram positive” microscopic organisms viz Staphylococcus aureus and Bacillus subtils two “Gram negative” microorganisms, for example, Pasturellamultocida and Escherichia coli was performed. The antimicrobial effects showed that 30% concentration of n-hexane black pepper (Piper nigrum L.) extract had a strong activity against Bacillus subtills (64±1) and 50% concentration of thyme (Thymus vulgaris L.) extract against Staphylococcus aureus (23±1). The consequences of against oxidant activities uncovered that the most noteworthy all out phenolic substance and complete flavonoid substance were noted after extract of plants. Free radical rummaging action was most extreme in n-hexane extract of plants. Reducing power assay was most extreme extracts of plants. Biofilm activity of plants extracts n-hexane against two bacteria viz Staphylococcus aureus and such as Escherichia coli was done. The extract shows maximum hemolysis of erythrocytes. It was seen that all verified microbial strains were sensitive “>0.82 activity value” to extract that showed a higher antimicrobial impact. Keep in outlook the significance of flavonoids and other bioactive compounds this investigation concentrated on evaluating natural compounds utilizing remove at various fixation.
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药用植物非极性化合物的抗菌作用
学习过于集中于鉴定可用于抗菌药物的化合物。药用植物在防治疾病、抗感染、抗氧化、抗恶性肿瘤等方面具有重要的药理作用。对百里香(thyymus vulgaris L.)和黑胡椒(Piper nigrum L.)的抗菌和抗氧化性能进行了研究。对肉桂(Cinnamomum verum L.)、绿茶(Camellia sinensis L.)、肉豆蔻(Myristicafragrans Houtt)进行了研究。药用植物通常在世界各地被吞食;绿茶含有大量未氧化的类黄酮,称为儿茶素。治疗性植物也证明可以减少对糖尿病有害的氧化压力,并改变内皮细胞的破裂。对其抗菌防癌性能进行了研究。采用圆盘扩散试验对所选菌株进行抑菌活性分析。考察了药用植物正己烷提取物对两种革兰氏阳性微生物(金黄色葡萄球菌和枯草芽孢杆菌)和两种革兰氏阴性微生物(多杀性巴氏杆菌和大肠杆菌)的抑菌活性。结果表明,30%浓度的正己烷黑胡椒提取物对枯草芽孢杆菌(64±1)的抑菌活性较强,50%浓度的百里香提取物对金黄色葡萄球菌(23±1)的抑菌活性较强。抗氧化活性的结果表明,植物提取后最值得注意的是全酚类物质和全黄酮类物质。植物正己烷提取物的自由基翻寻作用最为明显。还原力测定以植物提取物为最极端。研究了植物提取物正己烷对金黄色葡萄球菌和大肠杆菌的生物膜活性。提取物显示出最大的红细胞溶血。结果表明,所有验证的微生物菌株对提取物的活性值均>0.82,具有较高的抑菌效果。鉴于黄酮类化合物和其他生物活性化合物的意义,本研究主要对不同固定方式下利用去除的天然化合物进行了评价。
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