Xuewen Lu, Yan Wang, Dipankar Bandyopadhyay, Giorgos Bakoyannis
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引用次数: 0
Abstract
In this paper, we consider a class of partially linear transformation models with interval-censored competing risks data. Under a semiparametric generalized odds rate specification for the cause-specific cumulative incidence function, we obtain optimal estimators of the large number of parametric and nonparametric model components via maximizing the likelihood function over a joint B-spline and Bernstein polynomial spanned sieve space. Our specification considers a relatively simpler finite-dimensional parameter space, approximating the infinite-dimensional parameter space as n → ∞, thereby allowing us to study the almost sure consistency, and rate of convergence for all parameters, and the asymptotic distributions and efficiency of the finite-dimensional components. We study the finite sample performance of our method through simulation studies under a variety of scenarios. Furthermore, we illustrate our methodology via application to a dataset on HIV-infected individuals from sub-Saharan Africa.
在本文中,我们考虑了一类具有区间删失竞争风险数据的部分线性变换模型。在特定病因累积发病率函数的半参数广义几率规范下,我们通过最大化 B-样条曲线和伯恩斯坦多项式联合跨筛空间的似然函数,获得了大量参数和非参数模型成分的最优估计值。我们的规范考虑了相对简单的有限维参数空间,近似于 n → ∞ 的无限维参数空间,从而使我们能够研究所有参数的几乎确定的一致性和收敛率,以及有限维成分的渐近分布和效率。我们通过各种情况下的模拟研究,研究了我们方法的有限样本性能。此外,我们还将我们的方法应用于撒哈拉以南非洲地区的 HIV 感染者数据集,以说明我们的方法。
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.