Factors affecting post-vasectomy semen analysis compliance in home- and lab-based testing.

Charles Welliver, Jacob Zipkin, Brenda Lin, Dhruv Patel, Paul Feustel, Andrew McCullough
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Abstract

Introduction: We used a home-based (HB) post-vasectomy semen analysis (PVSA) between 2014 and 2017, but we have since reverted to local lab-based (LB) testing. In this study, we compared PVSA compliance rates in HB and LB test settings and describe factors that may influence completion rates.

Methods: We retrospectively identified patients who underwent vasectomy at our institution. Surgeons X and Y performed vasectomies from 2014-2017 using a HB immunochromatographic PVSA kit. From 2017-2020, surgeon X used a local LB PVSA. We collected data on PVSA completion status and patient demographics to perform two analyses. HB testing was examined by assessing all patients who had a vasectomy from 2014-2017. Another compared HB and LB testing by looking at surgeon X vasectomies from 2014-2017 and 2017-2020.

Results: We identified 285 patients who underwent vasectomy from 2014-2017 and were assessed with HB testing. Compliance with PVSA was 35% with HB PVSA. Age at vasectomy, number of children, and surgeon influenced PVSA completion in the 2014-2017 cohort. Surgeon X PVSA completion was 29% for the HB (n=136) testing cohort and 46% for the LB (n=201) cohort (odds ratio 0.47, 95% confidence interval 0.29-0.74). Again, more children decreased PVSA completion.

Conclusions: Compliance with PVSA testing was inadequate in both test settings, although it was significantly higher in local LB setting. Based on these findings, the convenience of HB testing appears to decrease compliance with PVSA, although surgeon factors may be influential. These findings may help surgeons identify factors that improve PVSA compliance rates.

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影响输精管结扎后精液分析依从性的家庭和实验室检测因素。
在2014年至2017年期间,我们使用了基于家庭(HB)的输精管切除术后精液分析(PVSA),但我们已经恢复到基于当地实验室(LB)的测试。在这项研究中,我们比较了HB和LB测试设置中的PVSA依从率,并描述了可能影响完成率的因素。方法:我们对在我院接受输精管切除术的患者进行回顾性分析。2014-2017年,外科医生X和Y使用HB免疫层析PVSA试剂盒进行了输精管切除术。从2017-2020年,X外科医生使用了局部LB PVSA。我们收集了PVSA完成状态和患者人口统计数据进行了两项分析。通过评估2014-2017年进行输精管切除术的所有患者来检查HB检测。另一项研究通过观察2014-2017年和2017-2020年的外科医生X输精管切除术来比较HB和LB测试。结果:我们确定了2014-2017年接受输精管切除术的285例患者,并进行了HB检测。HB PVSA依从性为35%。在2014-2017年队列中,输精管结扎年龄、儿童数量和外科医生影响PVSA完成。在HB组(n=136)和LB组(n=201)中,PVSA完成率分别为29%和46%(优势比0.47,95%可信区间0.29-0.74)。同样,更多的儿童减少了PVSA的完成度。结论:PVSA测试的依从性在两种测试环境中都是不足的,尽管在局部LB环境中明显更高。基于这些发现,尽管外科因素可能有影响,但HB检测的便利性似乎降低了PVSA的依从性。这些发现可能有助于外科医生确定提高PVSA依从率的因素。
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