硅基磁共振光谱微线圈的批量制备

R. Syms, M.M. Ahmad, I. Young, D. Gilderdale, D. Collins, M. Leach
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引用次数: 5

摘要

一种低成本的微线圈批量制造工艺,用于临床活检样品的磁共振(MR)光谱分析。导体是通过在深层光阻剂模具内电镀金属,在氧化的、固有的硅衬底上制造的。通过晶圆深反应离子蚀刻(DRIE)用于定义精确的样品体积和每个模具周围的模板切割,并且模具通过卡扣分离。单线圈和多线圈(亥姆霍兹型)传感器通过将部件堆叠在硅基板上形成。磁共振成像和光谱都证明了模型样品,具有较高的信噪比
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Batch fabrication of micro-coils for MR spectroscopy on silicon
A process for batch fabrication of low-cost microcoils for magnetic resonance (MR) spectroscopy of clinical biopsy samples is demonstrated. Conductors are fabricated on oxidized, intrinsic silicon substrates by electroplating metals inside a deep photoresist mould. Through-wafer deep reactive ion etching (DRIE) is used to define precise sample volumes and stencil cuts around each die, and dies are separated by snap-out. Single- and multiple-coil (Helmholtz-type) sensors are formed, by stacking parts on silicon baseplates. MR imaging and spectroscopy are both demonstrated on model samples, with high SNR
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