用于生物和化学传感器的可变干涉滤光片(VIF)

Celso M. Silva, Daniel A. Spegiorin, Tiago F. Silva, R. Onmori
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引用次数: 0

摘要

高分辨率和紧凑的波长探测器能够分辨入射光光谱信息的非常小的变化,是许多应用非常需要的,如片上实验室系统,生物传感器,芯片大小的探测器,片上荧光光谱,波长移位探测器,询问系统等。在这项工作中,介绍了一个可变干涉滤光器(VIF)的模拟,制造和校准,该滤光器由放置在两层薄膜之间的楔形法布里-珀罗腔构成,形成介电反射器。该装置构成一个滤光器,该滤光器将光谱信息转换为可由光电探测器阵列(PDA)测量的位置相关信号。为了优化其几何结构,我们研究了所设计的VIF根据其光学特性的性能。在此基础上,研制了一种可用于环境分析的多通道光谱探测器。为了证明这种可行性,提出了一种基本系统,该系统由安装在连接到专用电子模块的传感器矩阵顶部的VIF组成,用于测量和存储入射辐射数据的强度以及存在于微流体系统检测室中的分子的吸收光谱。该原型旨在分析生物液体、人类尿液,并将结果与使用标准商用仪器获得的结果进行比较。
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Variable Interference Filter (VIF) for biological and Chemical sensors
A high-resolution and compact wavelength detector capable of resolving very small changes in the spectral information of the incident light is highly desirable for many applications such as Lab-on-Chip systems, biosensors, chip-sized detectors, on-chip fluorescence spectrometry, wavelength shift detectors, interrogations system, and more. In this work is present the project, simulations, fabrications and calibration of a variable interference filter (VIF) constituted by a wedgeshaped Fabry-Perot cavity placed between two stacks of thin films, forming dielectric reflectors. This device constitutes an optical filter that converts the spectral information in a position dependent signal that can be measured by a photo detector array (PDA). We have investigated the performance of the designed VIF depending on its optical properties in order to optimize its geometrical configuration. With the results obtained we fabricated a multi-channel spectral detector that can be used in environmental analysis. To demonstrate this viability, it is proposed a basic system composed of a VIF mounted on top of a matrix of sensors connected to a dedicated electronic module, to measure and store the intensity of the incident radiation data and the absorption spectra of molecules present in a detection chamber of a microfluidic system. This prototype is aimed to analyze biological fluids, human urine, and results will be compared with results obtained using standard commercial instruments.
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