16.6双面无衬垫结构CMOS-CNT生物传感器阵列,用于医疗环境下的简单裸芯片测量

Jinhong Ahn, Jeaheung Lim, S. Kim, J. Yun, Changhyun Kim, Sang-Hoon Hong, Myoung-Jin Lee, Youngjune Park
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引用次数: 1

摘要

在表面使用纳米材料的CMOS传感器对于疾病的早期检测非常有效。在纳米材料中,碳纳米管(CNT)具有与生物分子大小直接相当的直径小(~1nm)和优异的电学特性,是一种理想的生物传感器材料。由于碳纳米管是在特殊的环境中化学形成的,为了在CMOS工艺中使用它,需要将许多电极形成阵列,并将碳纳米管溶液涂覆在电极阵列上。然而,为了防止焊盘之间的电短路,需要非常复杂的区域选择性碳纳米管涂层工艺。此外,芯片封装步骤——如导线键合、针对导线反应的芯片钝化、芯片上的微流控通道等——应谨慎应用。
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16.6 Double-side CMOS-CNT biosensor array with padless structure for simple bare-die measurements in a medical environment
CMOS sensors using nanomaterials on the surface are very effective for early detection of diseases. Among the nanomaterials, carbon nanotube (CNT) is an ideal biosensor material since it has a small diameter (~1nm) directly comparable to the size of biomolecules and excellent electrical characteristics. Because CNT is formed chemically in a special environment, to use it in a CMOS process, many electrodes are formed as an array and the CNT solution is coated on the electrode array. However, to prevent electrical shorts between bonding pads, very complicated area-selective CNT coating processes are required. Furthermore, chip packaging steps - such as wire bonding, chip passivation against reactions to the wire, microfluidic channels on the chip, etc. - should be carefully applied [1].
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