Implantable Interface for an Arm Neuroprosthesis

This paper presents an ongoing development of an arm neuroprosthesis implantable interface consisting of a quadrupole implantable cuff-electrode, a neural analog front-end, a low power Arduino microcontroller, an off the shelf 433MHz transmitter, and a 3.7V 430mAh Li-Po battery. Implantable cuff electrode made of PDMS and Au has been successfully fabricated and tested for biocompatibility. A low power and low noise analog front-end were designed to filter and amplify the electroneurogram signal sensed by the cuff-electrode. The system was tested in the laboratory with input signals similar to the actual biological signals, verifying the correct operation of the implantable device. Finally, the analog front-end module was encapsulated in PDMS and implanted in the hind limb of a swine giving valuable training and knowledge for further development of the neuroprosthesis implantable interface.