{"title":"光的力量 - 从牙科材料加工到诊断和治疗","authors":"Mohammed A. Hadis, A. Shortall, William M. Palin","doi":"10.2340/biid.v11.40308","DOIUrl":null,"url":null,"abstract":"Harnessing the power of light and its photonic energy is a powerful tool in biomedical applications. Its use ranges from biomaterials processing and fabrication of polymers to diagnostics and therapeutics. Dental light curable materials have evolved over several decades and now offer very fast (≤ 10 s) and reliable polymerization through depth (4–6 mm thick). This has been achieved by developments on two fronts: (1) chemistries with more efficient light absorption characteristics (camphorquinone [CQ], ~30 L mol-1 cm1 [ʎmax 470 nm]; monoacylphosphine oxides [MAPO], ~800 L mol-1 cm-1 [ʎmax 385 nm]; bisacylphosphine oxide [BAPO], ~1,000 L mol-1 cm-1 [ʎmax 385 nm]) as well mechanistically efficient and prolonged radical generation processes during and after light irradiation, and; (2) introducing light curing technologies (light emitting diodes [LEDs] and less common lasers) with higher powers (≤ 2 W), better spectral range using multiple diodes (short: 390–405 nm; intermediate: 410–450 nm; and long: 450–480 nm), and better spatial power distribution (i.e. homogenous irradiance). However, adequate cure of materials falls short for several reasons, including improper selection of materials and lights, limitations in the chemistry of the materials, and limitations in delivering light through depth. Photonic energy has further applications in dentistry which include transillumination for diagnostics, and therapeutic applications that include photodynamic therapy, photobiomodulation, and photodisinfection. Light interactions with materials and biological tissues are complex and it is important to understand the advantages and limitations of these interactions for successful treatment outcomes. This article highlights the advent of photonic technologies in dentistry, its applications, the advantages and limitations, and possible future developments.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"54 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The power of light – From dental materials processing to diagnostics and therapeutics\",\"authors\":\"Mohammed A. Hadis, A. 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引用次数: 0
摘要
利用光的力量及其光子能量是生物医学应用中的一个强大工具。其应用范围从生物材料加工和聚合物制造到诊断和治疗。牙科光固化材料经过几十年的发展,现在已经可以在深度(4-6 毫米厚)内实现非常快速(≤ 10 秒)和可靠的聚合。这主要得益于两个方面的发展:(1) 具有更高效光吸收特性的化学物质(樟脑醌 [CQ],~30 L mol-1 cm1 [ʎmax470纳米];单酰基氧化膦 [MAPO],~800 L mol-1 cm-1 [ʎmax385纳米];双酰基氧化膦 [BAPO], ~1,000 L mol-1 cm-1 [ʎmax 385 nm]),以及在光照射期间和之后的机械高效和长时间的激光灯,以及;(2) 引入光固化技术(发光二极管 [LED] 和不太常见的激光器),功率更高(≤ 2 W),使用多个二极管的光谱范围更广(短:390-405纳米;中间:410-450纳米;长:450-480纳米),以及更好的空间功率分布(即均匀辐照度)。即均匀的辐照度)。然而,由于多种原因,包括材料和光源选择不当、材料化学性质的限制以及通过深度传递光的限制,材料的充分固化并不理想。光子能量在牙科领域还有更多应用,包括用于诊断的透射照明,以及包括光动力疗法、光生物调节和光消毒在内的治疗应用。光与材料和生物组织之间的相互作用非常复杂,了解这些相互作用的优势和局限性对于取得成功的治疗效果非常重要。本文重点介绍光子技术在牙科中的应用、其优势和局限性以及未来可能的发展。
The power of light – From dental materials processing to diagnostics and therapeutics
Harnessing the power of light and its photonic energy is a powerful tool in biomedical applications. Its use ranges from biomaterials processing and fabrication of polymers to diagnostics and therapeutics. Dental light curable materials have evolved over several decades and now offer very fast (≤ 10 s) and reliable polymerization through depth (4–6 mm thick). This has been achieved by developments on two fronts: (1) chemistries with more efficient light absorption characteristics (camphorquinone [CQ], ~30 L mol-1 cm1 [ʎmax 470 nm]; monoacylphosphine oxides [MAPO], ~800 L mol-1 cm-1 [ʎmax 385 nm]; bisacylphosphine oxide [BAPO], ~1,000 L mol-1 cm-1 [ʎmax 385 nm]) as well mechanistically efficient and prolonged radical generation processes during and after light irradiation, and; (2) introducing light curing technologies (light emitting diodes [LEDs] and less common lasers) with higher powers (≤ 2 W), better spectral range using multiple diodes (short: 390–405 nm; intermediate: 410–450 nm; and long: 450–480 nm), and better spatial power distribution (i.e. homogenous irradiance). However, adequate cure of materials falls short for several reasons, including improper selection of materials and lights, limitations in the chemistry of the materials, and limitations in delivering light through depth. Photonic energy has further applications in dentistry which include transillumination for diagnostics, and therapeutic applications that include photodynamic therapy, photobiomodulation, and photodisinfection. Light interactions with materials and biological tissues are complex and it is important to understand the advantages and limitations of these interactions for successful treatment outcomes. This article highlights the advent of photonic technologies in dentistry, its applications, the advantages and limitations, and possible future developments.