{"title":"基于纳米酶的癌症诊断传感器","authors":"Olga Guliy, Lev Dykman","doi":"10.1016/j.biosx.2024.100512","DOIUrl":null,"url":null,"abstract":"<div><p>Many biosensor technologies that can precisely and sensitively identify biomarkers reflecting disease status are being developed to help with early cancer detection and anticancer treatment monitoring. The creation of sensors based on nanozymes is one of the novel approaches in the intricate diagnosis and treatment of cancers. Because natural enzyme sensors can be unstable and expensive, the use of nanozymes in biosensors offers a great substitute for this type of study. Nanozymes have a stable shelf life, great operational reliability, cheap cost, and outstanding catalytic activity. The technological approaches to generating nanozymes and their use in sensors are briefly described in the paper. A summary of the many kinds of biosensors based on diverse kinds of nanomaterials for the identification of cancer biomarkers is provided, along with a discussion of the latest developments and challenges in the field of nanozyme biosensors for use in cancer diagnosis.</p></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"19 ","pages":"Article 100512"},"PeriodicalIF":10.6100,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590137024000761/pdfft?md5=c564e41c482200bbd63670b988b5dd3d&pid=1-s2.0-S2590137024000761-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Nanozyme-based sensors for cancer diagnosis\",\"authors\":\"Olga Guliy, Lev Dykman\",\"doi\":\"10.1016/j.biosx.2024.100512\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Many biosensor technologies that can precisely and sensitively identify biomarkers reflecting disease status are being developed to help with early cancer detection and anticancer treatment monitoring. The creation of sensors based on nanozymes is one of the novel approaches in the intricate diagnosis and treatment of cancers. Because natural enzyme sensors can be unstable and expensive, the use of nanozymes in biosensors offers a great substitute for this type of study. Nanozymes have a stable shelf life, great operational reliability, cheap cost, and outstanding catalytic activity. The technological approaches to generating nanozymes and their use in sensors are briefly described in the paper. A summary of the many kinds of biosensors based on diverse kinds of nanomaterials for the identification of cancer biomarkers is provided, along with a discussion of the latest developments and challenges in the field of nanozyme biosensors for use in cancer diagnosis.</p></div>\",\"PeriodicalId\":260,\"journal\":{\"name\":\"Biosensors and Bioelectronics: X\",\"volume\":\"19 \",\"pages\":\"Article 100512\"},\"PeriodicalIF\":10.6100,\"publicationDate\":\"2024-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2590137024000761/pdfft?md5=c564e41c482200bbd63670b988b5dd3d&pid=1-s2.0-S2590137024000761-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biosensors and Bioelectronics: X\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590137024000761\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Biochemistry, Genetics and Molecular Biology\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors and Bioelectronics: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590137024000761","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
Many biosensor technologies that can precisely and sensitively identify biomarkers reflecting disease status are being developed to help with early cancer detection and anticancer treatment monitoring. The creation of sensors based on nanozymes is one of the novel approaches in the intricate diagnosis and treatment of cancers. Because natural enzyme sensors can be unstable and expensive, the use of nanozymes in biosensors offers a great substitute for this type of study. Nanozymes have a stable shelf life, great operational reliability, cheap cost, and outstanding catalytic activity. The technological approaches to generating nanozymes and their use in sensors are briefly described in the paper. A summary of the many kinds of biosensors based on diverse kinds of nanomaterials for the identification of cancer biomarkers is provided, along with a discussion of the latest developments and challenges in the field of nanozyme biosensors for use in cancer diagnosis.
期刊介绍：
Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.
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