利用同步辐射 X 射线散射研究的系统回顾和荟萃分析研究胶原基组织的变形

IF 7.9 2区 综合性期刊 Q1 CHEMISTRY, MULTIDISCIPLINARY Cell Reports Physical Science Pub Date : 2024-09-18 DOI:10.1016/j.xcrp.2024.102212
Lander Manrique, Mahmoud S. Moussa, Muhammad Talal Khan, Kawkab Tahboub, Robert O. Ritchie, Meisam Asgari, Elizabeth A. Zimmermann
{"title":"利用同步辐射 X 射线散射研究的系统回顾和荟萃分析研究胶原基组织的变形","authors":"Lander Manrique, Mahmoud S. Moussa, Muhammad Talal Khan, Kawkab Tahboub, Robert O. Ritchie, Meisam Asgari, Elizabeth A. Zimmermann","doi":"10.1016/j.xcrp.2024.102212","DOIUrl":null,"url":null,"abstract":"<p>Collagen fibrils are the building blocks of many tissues from fish scales and tendons to bone. Synchrotron small-angle X-ray scattering (SAXS) with <em>in situ</em> mechanical testing is a powerful tool to investigate collagen fibril deformation. There is a need to combine data from SAXS studies to investigate structure-function relationships. A literature search used the concepts of mechanical properties, collagen, and SAXS, with 52 articles meeting the eligibility criteria. Here, we report that mineralized tissues transfer a greater proportion of tissue-scale deformation to the fibril: 67% for cortical bone, 49% for tendon, 10% for ligament, and 3% for skin. Across non-mineralized tissues, tissues with less complexity and greater elastin content transfer less deformation to the fibril. The meta-analysis finds 20%–40% lower fibril strain in human aging and disease compared to controls, which contributes toward fracture risk. This synthesis demonstrates how variations in composition and structure tune material properties in collagen-based tissues.</p>","PeriodicalId":9703,"journal":{"name":"Cell Reports Physical Science","volume":null,"pages":null},"PeriodicalIF":7.9000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deformation of collagen-based tissues investigated using a systematic review and meta-analysis of synchrotron x-ray scattering studies\",\"authors\":\"Lander Manrique, Mahmoud S. Moussa, Muhammad Talal Khan, Kawkab Tahboub, Robert O. Ritchie, Meisam Asgari, Elizabeth A. Zimmermann\",\"doi\":\"10.1016/j.xcrp.2024.102212\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Collagen fibrils are the building blocks of many tissues from fish scales and tendons to bone. Synchrotron small-angle X-ray scattering (SAXS) with <em>in situ</em> mechanical testing is a powerful tool to investigate collagen fibril deformation. There is a need to combine data from SAXS studies to investigate structure-function relationships. A literature search used the concepts of mechanical properties, collagen, and SAXS, with 52 articles meeting the eligibility criteria. Here, we report that mineralized tissues transfer a greater proportion of tissue-scale deformation to the fibril: 67% for cortical bone, 49% for tendon, 10% for ligament, and 3% for skin. Across non-mineralized tissues, tissues with less complexity and greater elastin content transfer less deformation to the fibril. The meta-analysis finds 20%–40% lower fibril strain in human aging and disease compared to controls, which contributes toward fracture risk. This synthesis demonstrates how variations in composition and structure tune material properties in collagen-based tissues.</p>\",\"PeriodicalId\":9703,\"journal\":{\"name\":\"Cell Reports Physical Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":7.9000,\"publicationDate\":\"2024-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Reports Physical Science\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://doi.org/10.1016/j.xcrp.2024.102212\",\"RegionNum\":2,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Reports Physical Science","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1016/j.xcrp.2024.102212","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

摘要

胶原纤维是从鱼鳞、肌腱到骨骼等多种组织的组成部分。同步加速器小角 X 射线散射(SAXS)和原位机械测试是研究胶原纤维变形的有力工具。有必要结合 SAXS 研究的数据来研究结构与功能的关系。文献检索使用了力学性能、胶原蛋白和 SAXS 等概念,共有 52 篇文章符合资格标准。在此,我们报告了矿化组织将更大比例的组织尺度变形转移到纤维上的情况:皮质骨为 67%,肌腱为 49%,韧带为 10%,皮肤为 3%。在非矿化组织中,复杂性较低、弹性蛋白含量较高的组织转移到纤维的变形较少。荟萃分析发现,与对照组相比,人体衰老和疾病中的纤维应变降低了20%-40%,从而导致骨折风险。这篇综述展示了组成和结构的变化如何调整基于胶原蛋白的组织的材料特性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Deformation of collagen-based tissues investigated using a systematic review and meta-analysis of synchrotron x-ray scattering studies

Collagen fibrils are the building blocks of many tissues from fish scales and tendons to bone. Synchrotron small-angle X-ray scattering (SAXS) with in situ mechanical testing is a powerful tool to investigate collagen fibril deformation. There is a need to combine data from SAXS studies to investigate structure-function relationships. A literature search used the concepts of mechanical properties, collagen, and SAXS, with 52 articles meeting the eligibility criteria. Here, we report that mineralized tissues transfer a greater proportion of tissue-scale deformation to the fibril: 67% for cortical bone, 49% for tendon, 10% for ligament, and 3% for skin. Across non-mineralized tissues, tissues with less complexity and greater elastin content transfer less deformation to the fibril. The meta-analysis finds 20%–40% lower fibril strain in human aging and disease compared to controls, which contributes toward fracture risk. This synthesis demonstrates how variations in composition and structure tune material properties in collagen-based tissues.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Cell Reports Physical Science
Cell Reports Physical Science Energy-Energy (all)
CiteScore
11.40
自引率
2.20%
发文量
388
审稿时长
62 days
期刊介绍: Cell Reports Physical Science, a premium open-access journal from Cell Press, features high-quality, cutting-edge research spanning the physical sciences. It serves as an open forum fostering collaboration among physical scientists while championing open science principles. Published works must signify significant advancements in fundamental insight or technological applications within fields such as chemistry, physics, materials science, energy science, engineering, and related interdisciplinary studies. In addition to longer articles, the journal considers impactful short-form reports and short reviews covering recent literature in emerging fields. Continually adapting to the evolving open science landscape, the journal reviews its policies to align with community consensus and best practices.
期刊最新文献
Paper microfluidic sentinel sensors enable rapid and on-site wastewater surveillance in community settings Catalyzing deep decarbonization with federated battery diagnosis and prognosis for better data management in energy storage systems 4.8-V all-solid-state garnet-based lithium-metal batteries with stable interface Deformation of collagen-based tissues investigated using a systematic review and meta-analysis of synchrotron x-ray scattering studies Catalysis for plastic deconstruction and upcycling
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1