影响IIIB期宫颈癌合并肾积水患者双“J”型支架置入预后的预测因素

G. N. K. Dinatha, Anak Agung Gde Oka, K. Santosa
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引用次数: 0

摘要

目的:探讨影响IIIB期宫颈癌合并肾积水患者行双J型(DJ)支架置入术预后的预测因素。方法:对历史队列进行分析性观察研究。本研究纳入的患者是Sanglah医院的IIIB期宫颈癌伴肾积水并发症患者。我们分析了从诊断到植入DJ支架的时间范围、肾积水程度和肾小球滤过率对DJ支架置入结果的影响,即:下尿路症状(LUTS)、生活质量(QoL)和肾小球滤过率变化(GFR)。采用SPSS 25对数据进行制表和统计分析。结果:44例患者的平均年龄为51,93(±7.672)岁。晚期DJ支架置入增加严重LUTS的风险(RR: 3.103;95%置信区间:1.319—-7.301;p<0.001)。我们还发现低肾小球滤过率(肾功能差)与较差的生活质量显著相关(RR: 1.917;95%置信区间:1.296—-2.835;p < 0.001)。结论:延迟放置DJ支架与严重的LUTS症状相关,肾功能差导致生活质量差。
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Predictive Factors Influencing the Outcomes of Double “J” Stent Placement in Stage IIIB Cervical Cancer Patients With Hydronephrosis Complication
Objective: To determine the predictive factors that influence the outcome of Double “J” (DJ) stent placement in stage IIIB cervical cancer patients with hydronephrosis complications. Methods: An analytical observational study with a historical cohort was performed. Patients included in this study was patient with stage IIIB cervical cancer with hydronephrosis complication at Sanglah hospital. We analyzed the influence of time range since diagnosis until DJ stent placement, degree of hydronephrosis, and glomerular filtration rate on the outcomes of DJ stent placement namely: Lower urinary tract symptoms (LUTS), quality of life (QoL), and glomerular filtration rate changes (GFR). Data were tabulated and statistically analyzed using SPSS 25. Results: Of the 44 samples, the mean age of the patients was 51,93 (±7.672) years. Late DJ stent placement increase the risk of severe LUTS (RR: 3.103; 95%CI: 1.319-7.301; p<0.001) compared to patients with early DJ stent placement. We also found that a low glomerular filtration rate (bad renal function) is significantly associated with worse quality of life (RR: 1.917; 95%CI: 1.296-2.835; p<0.001). Conclusion: Delayed DJ stent placement is associated with severe LUTS symptoms, and poor renal function resulted in a poor quality of life.
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