Ophthalmologic manifestations in Acute Leukemia

Objective: To evaluate ophthalmological findings in patients with acute myeloid leukemia and acute lymphoblastic leukemia. Material and method: A single-center, retrospective, descriptive, observational analysis was conducted of patients with acute myeloid and acute lymphoblastic leukemia seen at the Department of Ophthalmology of Hospital de Pediatría Dr. Prof. Juan P. Garrahanin Buenos Aires, Argentina between March 1, 2017 and February 28, 2018. Results: Overall, 137 patients with acute leukemia who underwent ophthalmologic examination between March 1, 2017 and February 28, 2018 were included. Ages ranged from 0 to 18 years, with a mean of 7.9 years. Remarkably, 22.62%, i.e. more than one out of every five patients, of the cohort of patients with acute leukemia seen at our center and evaluated at the Department of Ophthalmology had some type of ocular manifestation. Conclusion: Our results show that ocular involvement occurs in a high percentage of patients with leukemia with a clear clinical, humoral, and prognostic correlation, suggesting that ophthalmologic evaluation should be routinely performed in these patients.