高剂量效率,超高分辨率非晶硒/CMOS混合数字x射线成像仪

C. Scott, A. Parsafar, A. El-Falou, P. Levine, K. Karim
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引用次数: 12

摘要

我们展示了5.6 μm × 6.25 μm像素间距直接转换非晶硒/CMOS混合x射线成像仪测量的x射线剂量效率结果。与现有的基于闪烁体的成像仪相比,我们的方法可以在20-60周期/mm的空间频率下实现高达100倍的DQE增益,这可以从根本上加速生物工程研究。在32次循环/mm时,测量到的MTF为50%,对应于16 μm的有效物体尺寸。我们还验证了MTF模型,该模型与实验结果一致,均方根误差为0.02。
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High dose efficiency, ultra-high resolution amorphous selenium/CMOS hybrid digital X-ray imager
We demonstrate measured X-ray dose efficiency results from a 5.6-μm × 6.25-μm pixel-pitch direct-conversion amorphous selenium/CMOS hybrid X-ray imager. Compared to existing scintillator-based imagers, our approach enables up to 100× gains in DQE at spatial frequencies of 20-60 cycles/mm, which could radically accelerate bioengineering research. The measured MTF is 50% at 32 cycles/mm, corresponding to a 16-μm effective object size. We also demonstrate a MTF model which confirms experimental results with an RMS error of 0.02.
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