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Metasurface-assisted bioelectronics: bridging photonic innovation with biomedical implants 超表面辅助生物电子学:连接光子创新与生物医学植入物
Q1 OPTICS Pub Date : 2025-11-24 DOI: 10.1038/s41377-025-02072-w
Mohammad Mohammadiaria, Shashi Bhushan Srivastava
Wireless cellular stimulation has been widely applied for bioengineering and bidirectional communication with the brain. Different technologies, such as photoelectrical stimulation as an alternative to optogenetics, have emerged for a wide range of remote therapeutic applications using light. Metasurfaces enable pixel-wise control of electric field distribution by engineering absorption and wavefront shaping, with responses tuned to incident light polarization, frequency, and phase, offering precise stimulation and wireless control in retinal, cochlear, and cardiac implants. Moreover, by leveraging terahertz (THz) band patches, reconfigurable metasurfaces controlled via FPGA and holography, and virtual reality-assisted designs, these interfaces can revolutionize bioelectronic medicine.
无线细胞刺激已广泛应用于生物工程和与大脑的双向通信。不同的技术,如光电刺激作为光遗传学的替代品,已经出现了广泛的使用光的远程治疗应用。超表面通过工程吸收和波前整形实现对电场分布的像素控制,并根据入射光的偏振、频率和相位调整响应,为视网膜、耳蜗和心脏植入物提供精确的刺激和无线控制。此外,通过利用太赫兹(THz)频段贴片,通过FPGA和全息控制的可重构元表面,以及虚拟现实辅助设计,这些接口可以彻底改变生物电子医学。
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引用次数: 0
Strong coupling of collective optical resonances in dielectric metasurfaces 介电超表面集体光学共振的强耦合
Q1 OPTICS Pub Date : 2025-11-24 DOI: 10.1038/s41377-025-02076-6
Izzatjon Allayarov, Vittorio Aita, Diane J. Roth, Boaz van Casteren, Anton Yu. Bykov, Andrey B. Evlyukhin, Anatoly V. Zayats, Antonio Calà Lesina
Dielectric metasurfaces can achieve strong light-matter interaction based on several types of collective (nonlocal) resonances, such as surface lattice resonances (SLRs) and quasi-bound states in the continuum (quasi-BICs). Spectral selectivity, field enhancement, and high and controllable Q-factors make these resonances appealing for technological applications in lasing, sensing, nonlinear optics, and quantum photon sources. An emerging challenge focuses on tailoring light-matter interaction via mode coupling and hybridisation between the fundamental resonances of a metasurface. While strong coupling phenomena have been demonstrated between various resonant modes, the interplay between collective resonances of different natures has not been observed to date. Here, we theoretically, numerically, and experimentally demonstrate the onset of coupling and hybridisation between symmetry-protected quasi-BICs and SLRs in a dielectric metasurface. We show the emergence of anticrossing (or Rabi splitting) in the strong coupling regime with suppression of reflection, observed under TE-polarised excitation, and the manifestation of an accidental BIC under TM-polarised illumination as a result of energy exchange between the participating collective resonances in the weak coupling regime. The first effect is accompanied by hybridised near fields of the modes. The observed coupling mechanisms can be controlled by modifying the angle of incidence, polarisation, and the surrounding environment. This foundational study on the coupling and hybridisation of collective resonances offers insights that can be leveraged for the design of metasurfaces with targeted quasi-aBIC and collective hybridised resonances. It could also open new possibilities to control the near fields associated with such resonances, with promising applications in tunable nanophotonics and light manipulation.
介电超表面可以基于几种类型的集体(非局部)共振,如表面晶格共振(SLRs)和连续介质中的准束缚态(quasi-BICs)实现强光-物质相互作用。光谱选择性、场增强和高可控q因子使这些共振在激光、传感、非线性光学和量子光子源等技术应用中具有吸引力。一个新出现的挑战集中在通过超表面基本共振之间的模式耦合和杂化来剪裁光-物质相互作用。虽然在各种共振模式之间已经证明了强耦合现象,但迄今为止尚未观察到不同性质的集体共振之间的相互作用。在这里,我们从理论上、数值上和实验上证明了介电超表面中对称保护的准bic和单反之间耦合和杂化的开始。我们展示了在te极化激发下反射抑制的强耦合区中反交叉(或拉比分裂)的出现,以及在弱耦合区中由于参与集体共振之间的能量交换而在tm极化照明下偶然BIC的表现。第一种效应伴随着模态近场的杂化。观察到的耦合机制可以通过改变入射角、偏振和周围环境来控制。这项关于集体共振耦合和杂化的基础研究为设计具有目标准abic和集体杂化共振的元表面提供了见解。它还可以为控制与这种共振相关的近场开辟新的可能性,在可调谐纳米光子学和光操纵方面有很好的应用前景。
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引用次数: 0
Open-source sub-nanometer stabilization system for super-resolution fluorescence microscopy 开源超分辨率荧光显微镜亚纳米稳定系统
Q1 OPTICS Pub Date : 2025-11-20 DOI: 10.1038/s41377-025-02022-6
Florencia Edorna, Florencia D. Choque, Giovanni Ferrari, Luciano A. Masullo, Piotr Zdańkowski, Guillermo P. Acuna, Philip Tinnefeld, Alan M. Szalai, Lucía F. Lopez, Andrés Zelcer, Fernando D. Stefani
Recent advances in fluorescence nanoscopy have pushed resolution to the 1–10 nm range, enabling the direct visualization of individual molecules even in crowded biological environments. Achieving this level of precision requires rigorous sample drift control. Techniques such as MINFLUX and RASTMIN, which rely on keeping the sample fixed within an excitation pattern, demand active drift correction to achieve their theoretical nanometer-scale resolution limits. Here, we present an active stabilization system for super-resolution microscopy that delivers sub-nm precision for hours. Featuring a simple optical design, the system can be added as a separate module to any fluorescence microscope. We also provide an open-source control software including a user-friendly graphical interface readily adaptable to different setups. We demonstrate the adaptability and performance of the stabilization system with p-MINFLUX and RASTMIN measurements performed in two different setups, reaching the theoretical Cramér-Rao Bound and resolving ~10 nm distances within DNA origami structures.
荧光纳米显微镜的最新进展已将分辨率提高到1-10纳米范围,即使在拥挤的生物环境中也能直接看到单个分子。达到这种精度水平需要严格的样品漂移控制。MINFLUX和RASTMIN等技术依赖于将样品固定在激发模式内,需要主动漂移校正以达到其理论纳米级分辨率极限。在这里,我们提出了一种超分辨率显微镜的主动稳定系统,可以提供几个小时的亚纳米精度。具有简单的光学设计,该系统可以作为一个单独的模块添加到任何荧光显微镜。我们还提供开源控制软件,包括易于适应不同设置的用户友好图形界面。我们用两种不同的装置进行了p-MINFLUX和RASTMIN测量,证明了稳定系统的适应性和性能,达到了理论上的cram - rao边界,并解决了DNA折纸结构内~10 nm的距离。
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引用次数: 0
Fast ultraviolet-C photonics: generating and sensing laser pulses on femtosecond timescales. 快速紫外- c光子学:在飞秒时间尺度上产生和感应激光脉冲。
Q1 OPTICS Pub Date : 2025-11-19 DOI: 10.1038/s41377-025-02042-2
Benjamin T Dewes,Tim Klee,Nathan D Cottam,Joseph J Broughton,Mustaqeem Shiffa,Tin S Cheng,Sergei V Novikov,Oleg Makarovsky,John W G Tisch,Amalia Patané
Photonic devices operating in the ultraviolet UV-C range (100-280 nm) have diverse applications from super-resolution microscopy to optical communications, and their advances promise to unlock new opportunities across science and technology. However, generating and detecting ultrafast light signals in this spectral range remains a major challenge. Here, we report an integrated UV-C source-sensor platform that combines phase-matched second-order processes in nonlinear optical crystals for the efficient generation of femtosecond UV-C laser pulses with a new class of room temperature photodetectors based on two-dimensional (2D) semiconductors. Unexpectedly, these 2D sensors exhibit a linear to super-linear photocurrent response to pulse energy, a highly desirable property, laying the foundation for UV-C-based photonics operating on femtosecond timescales over a wide range of pulse energies and repetition rates. As proof of concept, we demonstrate a free-space communication system.
在紫外- c范围内(100-280 nm)工作的光子器件具有从超分辨率显微镜到光通信的各种应用,它们的进步有望在科学和技术领域开启新的机遇。然而,在这个光谱范围内产生和检测超快光信号仍然是一个主要挑战。在这里,我们报告了一个集成的UV-C源传感器平台,该平台结合了非线性光学晶体中的相位匹配二阶过程,用于有效产生飞秒UV-C激光脉冲,以及一类基于二维(2D)半导体的新型室温光电探测器。出乎意料的是,这些2D传感器对脉冲能量表现出线性到超线性的光电流响应,这是一个非常理想的特性,为基于uv - c的光子学在飞秒时间尺度上在广泛的脉冲能量和重复率范围内工作奠定了基础。作为概念验证,我们演示了一个自由空间通信系统。
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引用次数: 0
Non-Hermitian systems based on 3D chirality enabled asymmetrical polarization switching and omni-polarizer action at an EP 基于三维手性的非厄米系统在极压下实现了不对称极化开关和全极化作用
Q1 OPTICS Pub Date : 2025-11-18 DOI: 10.1038/s41377-025-01960-5
Xianhui Fu, Hao Hu, Jiawei Zhang, Jiwei Qi, Sihao Zhang, Qiang Wu, Yao Lu, Zongqiang Chen, Jing Chen, Xuanyi Yu, Qian Sun, Jingjun Xu
Asymmetric mode/state switching and omni-polarizer action have demonstrated application potential and can be realized in non-Hermitian systems, which required a slow encircling process in the non-Hermitian parameter space in general. Is it possible to achieve the above functions only at an exceptional point (EP) without the encircling process? Here, we propose constructing a non-Hermitian system using three-dimensional (3D) chiral materials to realize the above functions at an EP instead of through the encircling process. Our results show that the 3D chiral non-Hermitian system exhibits properties that are quite different from those of traditional non-Hermitian optical systems. In our system, the eigenstates are different when propagating forward and backward, thus enabling asymmetric state switching. At the EP, the degenerate eigenstates of forward and backward propagations of the system become mutually orthogonal, which enables the system to act as an omni-polarizer. Crucially, to validate our claims, we propose a straightforward and widely applicable method to adjust a 3D chiral non-Hermitian system from a state far from an EP to near an EP. Based on this, we construct a free-space optical 3D chiral non-Hermitian system experimentally to directly observe the evolution of light polarization states near the EP. The experimental results prove that the proposed optical systems can achieve asymmetric state switching and omni polarizers at the EP, which is consistent with our theoretical expectations. Our work holds promise for various 3D chiral non-Hermitian optical applications, such as highly sensitive chirality measurements and polarization manipulation.
非对称模式/状态切换和全偏振作用在非厄米系统中具有应用潜力,而非厄米系统通常需要在非厄米参数空间中进行缓慢的包环过程。是否有可能仅在例外点(EP)实现上述功能而不进行环绕过程?在这里,我们提出用三维(3D)手性材料构建一个非厄米系统来实现上述功能,而不是通过环绕过程。我们的研究结果表明,三维手性非厄米光学系统具有与传统的非厄米光学系统截然不同的性质。在我们的系统中,当向前和向后传播时,特征态是不同的,从而实现非对称状态切换。在极值处,系统的前向传播和后向传播的简并本征态相互正交,使系统具有全偏振作用。至关重要的是,为了验证我们的观点,我们提出了一种简单且广泛适用的方法来将3D手性非厄米系统从远离EP的状态调整到接近EP的状态。在此基础上,我们通过实验构建了一个自由空间光学三维手性非厄米系统,直接观测光偏振态在EP附近的演化。实验结果表明,所提出的光学系统可以在极压下实现非对称状态切换和全偏振,这与我们的理论预期一致。我们的工作为各种3D手性非厄米光学应用提供了希望,例如高灵敏度手性测量和偏振操纵。
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引用次数: 0
Double-chirped mirrors expand the bandwidth of infrared frequency combs 双啁啾镜扩大了红外频率梳的带宽
Q1 OPTICS Pub Date : 2025-11-13 DOI: 10.1038/s41377-025-02078-4
Jacob B. Khurgin
A novel dispersion-compensation scheme based on double-chirped Bragg mirrors is implemented in a mid-infrared quantum cascade laser. As a result, stable and broadband frequency combs are generated, which are indispensable for high-precision applications in spectroscopy and metrology.
在中红外量子级联激光器中实现了一种基于双啁啾布拉格反射镜的色散补偿方案。因此,产生了稳定的宽带频率梳,这对于光谱学和计量学中的高精度应用是必不可少的。
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引用次数: 0
Light structuring via nonlinear total angular momentum addition with flat optics 平面光学非线性总角动量相加的光结构
Q1 OPTICS Pub Date : 2025-11-12 DOI: 10.1038/s41377-025-02004-8
Evgenii Menshikov, Paolo Franceschini, Kristina Frizyuk, Ivan Fernandez-Corbaton, Andrea Tognazzi, Alfonso Carmelo Cino, Denis Garoli, Mihail Petrov, Domenico de Ceglia, Costantino De Angelis
Shaping the structure of light with flat optical devices has driven significant advancements in our fundamental understanding of light and light-matter interactions, and enabled a broad range of applications, from image processing and microscopy to optical communication, quantum information processing, and the manipulation of microparticles. Yet, pushing the boundaries of structured light beyond the linear optical regime remains an open challenge. Nonlinear optical interactions, such as wave mixing in nonlinear flat optics, offer a powerful platform to unlock new degrees of freedom and functionalities for generating and detecting structured light. In this study, we experimentally demonstrate the non-trivial structuring of third-harmonic light enabled by the addition of total angular momentum projection in a nonlinear, isotropic flat optics element—a single thin film of amorphous silicon. We identify the total angular momentum projection and helicity as the most critical properties for analyzing the experimental results. The theoretical approach we propose, supported by numerical simulations, offers quantitative predictions for light structuring through nonlinear wave mixing under various pumping conditions, including vectorial and non-paraxial pump light. Notably, we reveal that the shape of third-harmonic light is highly sensitive to the polarization state of the pump. Our findings demonstrate that harnessing the addition of total angular momentum projection in nonlinear wave mixing can be a powerful strategy for generating and detecting precisely controlled structured light.
用平面光学器件塑造光的结构已经推动了我们对光和光物质相互作用的基本理解的重大进步,并实现了广泛的应用,从图像处理和显微镜到光通信,量子信息处理和微粒操纵。然而,将结构光的边界推进到线性光学之外仍然是一个开放的挑战。非线性光学相互作用,如非线性平面光学中的波混频,提供了一个强大的平台来解锁新的自由度和功能,以产生和检测结构光。在这项研究中,我们通过实验证明了三次谐波光的非平凡结构是通过在非线性、各向同性的平面光学元件(非晶硅薄膜)中添加总角动量投影实现的。我们认为总角动量投影和螺旋度是分析实验结果最关键的性质。我们提出的理论方法,在数值模拟的支持下,提供了在各种泵浦条件下,包括矢量和非旁轴泵浦光下,通过非线性波混合的光结构的定量预测。值得注意的是,我们发现三次谐波光的形状对泵浦的偏振状态高度敏感。我们的研究结果表明,在非线性波混合中利用总角动量投影可以成为产生和检测精确控制的结构光的有力策略。
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引用次数: 0
Correction: Deep-learning-based gas identification by time-variant illumination of a single micro-LED-embedded gas sensor 更正:通过单个微型led嵌入式气体传感器的时变照明进行基于深度学习的气体识别
Q1 OPTICS Pub Date : 2025-11-11 DOI: 10.1038/s41377-025-02023-5
Incheol Cho, Kichul Lee, Young Chul Sim, Jae-Seok Jeong, Minkyu Cho, Heechan Jung, Mingu Kang, Yong-Hoon Cho, Seung Chul Ha, Kuk-Jin Yoon, Inkyu Park
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引用次数: 0
Triboluminescence of metal halide perovskite films 金属卤化物钙钛矿薄膜的摩擦发光
Q1 OPTICS Pub Date : 2025-11-06 DOI: 10.1038/s41377-025-02032-4
Hao Tian, Fengke Sun, Jun Chen, Fusai Sun, Xiaotao Liu, Yang Li, Zhanjun Zhu, Junxue Guo, Bo Zhou, Xin Guo, Can Li
Metal halide perovskites (MHPs) have shown fantastic properties such as photoelectric conversion, electroluminescence, light amplification, ferroelectricity, and flexoelectricity, becoming versatile materials in diverse fields. Herein, we report a previously undiscovered nature of the MHP film, i.e. triboluminescence (TL), and elucidate its underlying mechanism. The TL response is triggered when an MHP film is scraped by specific materials (like Cu, Au, Pt) with a lower Fermi level than that of the MHP. The friction induces electron transfer from MHP to scraper, generating a positive electrostatic field on the surface of the MHP film, which leads to stretched MHP lattices owing to electrostatic repulsion, consequently enhancing fluorescence and charge carrier lifetime. If the friction material (like Al) has a higher Fermi level, electron transfer process, electrostatic field direction, and lattice structure change are just the opposite, resulting in reduced fluorescence. This work unveils the TL phenomenon of the MHP film and the unique mechanism, opening up new avenues for explorations on the appealing MHPs.
金属卤化物钙钛矿(MHPs)具有光电转换、电致发光、光放大、铁电性和挠性等优异的性能,成为多种领域的通用材料。在此,我们报告了以前未发现的MHP薄膜的性质,即摩擦发光(TL),并阐明了其潜在的机制。当MHP薄膜被费米能级低于MHP的特定材料(如Cu、Au、Pt)刮擦时,就会触发TL响应。摩擦诱导电子从MHP向刮刀转移,在MHP膜表面产生正静电场,静电斥力导致MHP晶格拉伸,从而增强荧光和载流子寿命。如果摩擦材料(如Al)具有较高的费米能级,则电子转移过程、静电场方向和晶格结构变化正好相反,导致荧光降低。这项工作揭示了MHP膜的TL现象和独特的机制,为探索具有吸引力的MHP开辟了新的途径。
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引用次数: 0
Measurement-device-independent continuous variable entanglement witness in a quantum network 量子网络中与测量设备无关的连续变量纠缠见证
Q1 OPTICS Pub Date : 2025-11-03 DOI: 10.1038/s41377-025-02039-x
Jing Fu, Xutong Wang, Shengshuai Liu, Jietai Jing
The reliable detection of entanglement plays a crucial role in the construction of quantum networks. The conventional entanglement witness (EW) method has high requirements for measurement device and relies on reliable implementation of the measurement. With unreliable measurement device, EW process can be easily attacked by eavesdroppers, which can lead to incorrect entanglement detection results. Therefore, a feasible and secure measurement device independent entanglement witness (MDIEW) method is desired for constructing quantum networks. Here, we detect the continuous variable entanglement by a MDIEW in a quantum network. It is demonstrated that the conventional EW method can be affected when the local oscillator intensity is changed, while the MDIEW method can detect entanglement between users without being affected. Our results provide a trustworthy method to detect entanglement, which is an important step for constructing secure quantum networks.
量子纠缠的可靠检测在量子网络的构建中起着至关重要的作用。传统的纠缠见证法对测量装置的要求较高,且依赖于测量的可靠实现。由于测量装置不可靠,电子战过程容易受到窃听者的攻击,从而导致不正确的纠缠检测结果。因此,需要一种可行且安全的测量设备独立纠缠见证(MDIEW)方法来构建量子网络。在这里,我们用MDIEW检测量子网络中的连续变量纠缠。结果表明,当本振强度发生变化时,传统的电子战方法会受到影响,而MDIEW方法可以在不受影响的情况下检测用户之间的纠缠。我们的研究结果提供了一种可靠的方法来检测纠缠,这是构建安全量子网络的重要一步。
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引用次数: 0
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