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Oral Cancer - Current Concepts and Future Perspectives最新文献

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Way to Cure Oral Squamous Cell Carcinoma with Theranostics and Nanoparticular Approaches 口腔鳞状细胞癌的治疗与纳米粒子治疗方法
Pub Date : 2022-01-07 DOI: 10.5772/intechopen.100181
Sankha Bhattacharya
One of the most prevalent forms of oral cancer is oral squamous cell carcinoma (OSCC), a major cause of morbidity and mortality worldwide. Following a definite oral cancer diagnosis, OSCC is typically treated with a multidisciplinary approach including surgery, chemotherapy, and radiation. In contrast, conventional chemotherapy medicines may be ineffective and have a range of side effects. Many techniques have been proved and authorized for treatment and diagnostics of different types of oral cancer, while others are currently being investigated in clinical trials. This book chapter is aimed to explain the current preclinical status of nano-based techniques to successfully diagnose and treat OSCC. This book chapter would also emphasize recent theranostics approaches utilized to cure OSCC. Nanotechnology also improved cancer biomarker detection, making them faster and more sensitive. To overcome these constraints and improve in situ drug delivery, various nanoparticles have been employed as innovation drivers.
口腔鳞状细胞癌(OSCC)是最常见的口腔癌之一,是世界范围内发病率和死亡率的主要原因。在明确的口腔癌诊断后,OSCC通常采用多学科方法治疗,包括手术、化疗和放疗。相比之下,传统的化疗药物可能是无效的,并有一系列的副作用。许多技术已被证实并被授权用于治疗和诊断不同类型的口腔癌,而其他技术目前正在临床试验中进行研究。本章旨在解释目前基于纳米技术成功诊断和治疗OSCC的临床前状态。本章还将强调最近用于治疗OSCC的治疗方法。纳米技术还改善了癌症生物标志物的检测,使它们更快、更敏感。为了克服这些限制并改善原位给药,各种纳米颗粒被用作创新驱动因素。
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Oral Cancer - Current Concepts and Future Perspectives
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