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Student conceptualizations and predictions of substitution and elimination reactions: what are they seeing on the page?† 学生对取代反应和消除反应的概念和预测:他们在纸上看到了什么?†
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-29 DOI: 10.1039/D4RP00204K
Kevin H. Hunter, Lauren A. Groenenboom, Ayesha Farheen and Nicole M. Becker

The current study aims to contribute to the literature on how organic chemistry students weigh various factors when predicting products of substitution and elimination reactions. This study focuses specifically on these mechanism types, as they are often the first instances where students must consider the “how” and the “why” of how reactions occur. Previous literature highlights that such reasoning can be challenging. To better support our students, it is essential to understand how they conceptualize these mechanisms. Here, we present results from an investigation into how students compare bimolecular and unimolecular substitution and elimination reactions (SN1, SN2, E1, E2). Students completed tasks involving case comparisons and “predict-the-product” exercises. Through the analysis of nine semi-structured interviews using coordination class theory, we found that (1) students placed a greater emphasis on the importance of the starting substrate in the outcome of a reaction, and (2) focused less on the function of the nucleophile or base in each reaction. Using coordination class theory, we identified visual features and knowledge elements that students coordinated, allowing us to create “resource graphs” that represented students’ conceptualizations. These graphs helped visualize the trajectories of students’ predictions by illustrating how they balanced multiple factors. We discuss implications for supporting students in distinguishing among reaction mechanisms.

目前的研究旨在为有机化学学生在预测取代和消除反应的产物时如何权衡各种因素的文献做出贡献。本研究特别关注这些机制类型,因为它们通常是学生必须考虑反应如何发生的“如何”和“为什么”的第一个实例。先前的文献强调,这样的推理可能具有挑战性。为了更好地支持我们的学生,有必要了解他们如何概念化这些机制。在这里,我们提出了一项关于学生如何比较双分子和单分子取代和消除反应(SN1, SN2, E1, E2)的调查结果。学生们完成的任务包括案例比较和“预测产品”练习。通过使用配位课堂理论对9个半结构化访谈进行分析,我们发现(1)学生更强调起始底物在反应结果中的重要性,(2)较少关注亲核试剂或碱在每个反应中的作用。使用协调类理论,我们确定了学生协调的视觉特征和知识元素,允许我们创建代表学生概念化的“资源图”。这些图表通过说明学生如何平衡多种因素,帮助可视化学生预测的轨迹。我们讨论了支持学生区分反应机制的意义。
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引用次数: 0
Self-regulated learning strategies for success in an online first-year chemistry course 一年级在线化学课程成功的自主学习策略
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-12 DOI: 10.1039/D4RP00159A
Langanani Rakhunwana, Angelique Kritzinger and Lynne A. Pilcher

During their first year of study at university, many students encounter challenges in developing learning strategies that align with success in the courses in which they are enrolled. The emergence of the COVID-19 pandemic heightened the challenges as universities were compelled to transition to online learning. Therefore, this study investigated the self-reported use of learning strategies in a first-year chemistry course delivered online due to the COVID-19 pandemic to identify learning strategies associated with success. Grounded in self-regulated learning (SRL) theory, a case study approach with an explanatory mixed methods design was adopted. Quantitative data were collected using a hybrid of the Motivated Strategies for Learning Questionnaire and the Online Self-regulated Learning Questionnaire. Follow-up open-ended questions were emailed to the students for the qualitative part of the study. Statistical analysis of the quantitative data was performed using SPSS and RUMM2030, while thematic analysis was applied to the qualitative data. Students reported more frequent use of SRL strategies of environment structuring, effort regulation, and elaboration. Conversely, critical thinking, task strategies, help-seeking, and peer learning were reportedly used less often. SRL strategies linked with success in the course were identified as effort regulation, goal setting, and time management. The findings from the qualitative data revealed an impact of online learning due to the pandemic on the use of peer learning and help-seeking strategies. The paper discusses the implications of these findings for educational practices, particularly in the context of hybrid learning in the post-pandemic era.

在大学的第一年,许多学生在制定学习策略时遇到了挑战,这些策略与他们所注册的课程的成功相一致。随着新冠肺炎大流行的出现,大学被迫转向在线学习,这加剧了挑战。因此,本研究调查了因COVID-19大流行而在线提供的一年级化学课程中自我报告的学习策略使用情况,以确定与成功相关的学习策略。本研究以自我调节学习理论为基础,采用混合解释方法设计的个案研究方法。定量数据收集使用混合动机学习策略问卷和在线自我调节学习问卷。后续的开放式问题通过电子邮件发送给学生,用于研究的定性部分。定量数据采用SPSS和RUMM2030进行统计分析,定性数据采用专题分析。学生报告更频繁地使用SRL策略的环境结构、努力调节和阐述。相反,据报道,批判性思维、任务策略、求助和同伴学习的使用频率较低。与课程成功相关的SRL策略包括努力调节、目标设定和时间管理。定性数据的调查结果显示,由于大流行,在线学习对同侪学习和寻求帮助策略的使用产生了影响。本文讨论了这些发现对教育实践的影响,特别是在大流行后时代混合学习的背景下。
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引用次数: 0
Student's study behaviors as a predictor of performance in general chemistry I 学生学习行为对普通化学成绩的预测作用1
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-11 DOI: 10.1039/D3RP00207A
Lorraine Laguerre Van Sickle and Regina F. Frey

General chemistry is often the first course taken by students interested in careers in STEM and health fields, and therefore, is considered an essential course for the success and retention of students in these fields. Prior studies have shown study habits and skills to be related to student performance in college-level courses, including STEM courses. Previous chemistry studies have focused on deep versus surface approaches to studying, how affective variables (e.g., self-efficacy) affect study habits, and how students study week to week. Literature has also shown that students’ management of their general study time can impact their performance, with distraction while studying becoming an increasing challenge for students. This study examined first-semester general-chemistry students' study behaviors (both their explicit learning strategies and study-time management practices) focusing on their exam preparation and that relationship to exam performance when controlling for prior knowledge and class attendance. Key findings include: (1) students, on average, employed two active strategies for exam preparation, dedicated half of their study time to active strategies, and were distracted 26% of the time. (2) While active strategies positively influenced exam performance and passive strategies had a negative impact, not all active strategies were equally effective. (3) The percentage of study time spent on active strategies correlated positively with performance, whereas higher distraction levels during exam preparation negatively affected outcomes. Understanding student exam-study behaviors and their effects on exam performance can help instructors support students more effectively by teaching them study strategies effective for their courses.

普通化学通常是对STEM和健康领域的职业感兴趣的学生的第一门课程,因此被认为是这些领域学生成功和保留的必要课程。之前的研究表明,学习习惯和技能与学生在大学水平课程中的表现有关,包括STEM课程。以前的化学研究侧重于深层与表层的学习方法,情感变量(如自我效能感)如何影响学习习惯,以及学生如何每周学习。文献还表明,学生对一般学习时间的管理会影响他们的表现,学习时分心对学生来说是一个越来越大的挑战。本研究考察了第一学期普通化学学生的学习行为(包括他们的显性学习策略和学习时间管理实践),重点关注他们的考试准备,以及在控制先验知识和课堂出勤率的情况下,他们与考试成绩的关系。主要发现包括:(1)学生平均使用两种积极的备考策略,将一半的学习时间用于积极的备考策略,26%的时间被分散注意力。(2)虽然主动策略对考试成绩有积极影响,而被动策略对考试成绩有消极影响,但并非所有的主动策略都同样有效。(3)在积极学习策略上花费的学习时间百分比与成绩呈正相关,而在备考过程中较高的分心水平对成绩有负相关影响。了解学生的应试学习行为及其对考试成绩的影响可以帮助教师通过教授有效的学习策略来更有效地支持学生。
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引用次数: 0
‘Seeing’ chemistry: investigating the contribution of mental imagery strength on students’ thinking in relation to visuospatial problem solving in chemistry† “看见”化学:研究心理意象强度对学生在化学中解决视觉空间问题的思维的贡献
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-11 DOI: 10.1039/D4RP00234B
Lauren Baade, Effie Kartsonaki, Hassan Khosravi and Gwendolyn A. Lawrie

Effective learning in chemistry education requires students to understand visual representations across multiple conceptual levels. Essential to this process are visuospatial skills which enable students to interpret and manipulate these representations effectively. These abilities allow students to construct mental models that support problem solving and decision making, improving their understanding of complex concepts, for example chemical structures and reactions. The impact of individual differences in mental imagery, such as aphantasia and hyperphantasia, on chemistry students’ spatial thinking when engaging with visual representations is not well understood. This paper presents two exploratory studies that examine how the vividness of mental imagery is related to student outcomes in chemistry-related visuospatial problem solving. The first study quantitatively assessed the performance of first-year university students in tasks requiring complex visual and spatial reasoning within a chemistry context. The second study, involving the same participants, used qualitative interview data to investigate their cognitive strategies with a focus on how their mental imagery impacts their problem-solving approaches. Preliminary results suggest that the vividness of students’ visual mental imagery did not significantly impact their ability to spatially reason with visual representations in chemistry. Our findings also indicate that students with aphantasia may employ alternative strategies that mitigate their lack of visual mental imagery. This paper highlights the need for further research into the diversity of cognitive mechanisms employed by chemistry students of varying mental imagery capabilities.

在化学教育中,有效的学习要求学生理解跨多个概念层次的视觉表征。这个过程的关键是视觉空间技能,它使学生能够有效地解释和操纵这些表征。这些能力使学生能够构建支持解决问题和决策的心智模型,提高他们对复杂概念的理解,例如化学结构和反应。心理意象的个体差异(如幻像和超幻像)对化学学生参与视觉表征时空间思维的影响尚不清楚。本文提出了两项探索性研究,探讨了心理意象的生动性与学生解决化学相关视觉空间问题的结果之间的关系。第一项研究定量评估了大学一年级学生在化学背景下复杂的视觉和空间推理任务中的表现。第二项研究涉及同样的参与者,使用定性访谈数据调查他们的认知策略,重点是他们的心理意象如何影响他们解决问题的方法。初步结果表明,学生视觉心理意象的生动性对其化学视觉表征的空间推理能力没有显著影响。我们的研究结果还表明,患有失视症的学生可能会采用其他策略来减轻他们视觉心理意象的缺乏。本文强调需要进一步研究不同心理意象能力的化学学生认知机制的多样性。
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引用次数: 0
Chemical bonding in Swedish upper secondary school education: a force-based teaching model for enhanced understanding 瑞典高中教育中的化学键:一种增强理解的以力为基础的教学模式
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-09 DOI: 10.1039/D4RP00258J
Catalin Koro Arvidsson

This study investigates if a force-based teaching approach, based on quantum mechanical principles and developed in a lesson study, would enhance the understanding of chemical bonding among upper secondary school students. The teaching approach was based on research on the teaching and learning of chemical bonding. The study included first-year students in upper secondary school in a pretest–intervention–posttest design. During four lessons the students were introduced to the underlying forces leading to the formation of all chemical bonds, specifically focusing on ionic- and covalent bonds. The first lesson, which included a presentation of coulombic interaction as a common basis of bond formation, was developed and improved through a lesson study. The lesson was revised based on feedback from 75 students describing why chemical bondings occur. After the four-lesson series about chemical bonding, a total of 67 of the 75 enrolled students had completed both a pre- and a posttest. The students’ answers to the tests were analyzed based on Bernstein's theory of vertical hierarchical and vertical horizontal discourse. The results of the posttests show that 60% of the students demonstrated solely or predominantly vertical hierarchical knowledge structure. These results indicate that most of the students could understand the force-based approach of chemical bonding by using a general theory, spanning over a wide range of the natural science field, with an abstract and specialized language. Moreover, the students who internalized a hierarchichal knowledge discourse about chemical bonding earned higher final grades in the upper secondary school chemistry when compared to students using a horizontal knowledge discourse, indicating that a force-based approach might facilitate a deeper understanding of other subareas within chemistry. In chemistry education research, the effect of using a force-based approach to teach chemical bonding has not previously been widely tested among upper secondary school students. This study responds to the need to test alternative teaching models to facilitate students’ understanding of chemical bonding.

本研究旨在探讨一种基于量子力学原理并在课堂研究中发展的基于力的教学方法是否能提高高中生对化学键的理解。在对化学键的教与学进行研究的基础上,提出了一种教学方法。本研究采用前测-干预-后测设计,研究对象为高中一年级学生。在四节课中,学生们被介绍了导致所有化学键形成的潜在力量,特别是离子键和共价键。第一课,包括库仑相互作用作为键形成的共同基础的介绍,是通过课程研究发展和完善的。这堂课是根据75名学生描述化学键发生的原因的反馈进行修改的。在四节关于化学键的系列课程之后,75名注册学生中共有67人完成了前测和后测。根据Bernstein的纵向层次理论和纵向水平话语理论对学生的回答进行分析。后测结果显示,60%的学生完全或主要表现为垂直层次知识结构。这些结果表明,大多数学生可以用抽象和专业的语言,用一个涵盖广泛自然科学领域的一般理论来理解基于力的化学键方法。此外,与使用水平知识话语的学生相比,内化关于化学键的分层知识话语的学生在高中化学中获得了更高的最终成绩,这表明基于力的方法可能有助于更深入地理解化学中的其他子领域。在化学教育研究中,使用基于力的方法来教授化学键的效果以前没有在高中生中进行过广泛的测试。本研究回应了测试替代教学模式的需要,以促进学生对化学键的理解。
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引用次数: 0
Design, development, and evaluation of the organic chemistry representational competence assessment (ORCA)† 设计,开发和评估有机化学代表性能力评估(ORCA)†
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-11-04 DOI: 10.1039/D3RP00188A
Lyniesha Ward, Fridah Rotich, Jeffrey R. Raker, Regis Komperda, Sachin Nedungadi and Maia Popova

This paper describes the design and evaluation of the rganic chemistry epresentational ompetence ssessment (ORCA). Grounded in Kozma and Russell's representational competence framework, the ORCA measures the learner's ability to interpret, translate, and use six commonly used representations of molecular structure (condensed structures, Lewis structures, skeletal structures, wedge-dash diagrams, Newman projections, and chair conformations). Semi-structured interviews with 38 first-semester organic chemistry learners informed the development of the ORCA items. The ORCA was developed and refined through three pilot administrations involving a total of 3477 first-semester organic chemistry students from multiple institutions. The final version of the ORCA was completed by 1494 students across five institutions. Various analyses provided evidence for the validity and reliability of the data generated by the assessment. Both one-factor and three-factor correlated structures were explored via confirmatory factor analysis. The one-factor model better captured the underlying structure of the data, which suggests that representational competence is better evaluated as a unified construct rather than as distinct, separate skills. The ORCA data reveal that the representational competence skills are interconnected and should consistently be reinforced throughout the organic chemistry course.

本文介绍了有机化学表征能力评价(ORCA)的设计与评价。ORCA以Kozma和Russell的表征能力框架为基础,测量学习者解释、翻译和使用六种常用的分子结构表征(凝聚结构、Lewis结构、骨骼结构、楔形虚线图、纽曼投影和椅子构象)的能力。对38名第一学期有机化学学习者的半结构化访谈为ORCA项目的开发提供了信息。ORCA是通过三个试点管理部门开发和完善的,涉及来自多个机构的3477名第一学期有机化学学生。ORCA的最终版本由来自五所院校的1494名学生完成。各种分析为评估产生的数据的有效性和可靠性提供了证据。通过验证性因子分析探索单因素和三因素的相关结构。单因素模型更好地捕捉了数据的底层结构,这表明表征能力更好地作为一个统一的结构来评估,而不是作为不同的、独立的技能来评估。ORCA数据显示,表征能力技能是相互关联的,应该在整个有机化学课程中不断加强。
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引用次数: 0
Psychometric analysis of the resonance concept inventory† 共振概念量表的心理测量分析
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-10-29 DOI: 10.1039/D4RP00170B
Grace C. Tetschner and Sachin Nedungadi

Many undergraduate chemistry students hold alternate conceptions related to resonance—an important and fundamental topic of organic chemistry. To help address these alternate conceptions, an organic chemistry instructor could administer the resonance concept inventory (RCI), which is a multiple-choice assessment that was designed to identify resonance-related alternate conceptions held by organic chemistry students. In this study, two iterations of the RCI were administered to undergraduate organic chemistry students: the RCI-Pilot (N = 484) and the RCI-Final (N = 595). Evidence was collected to support the quality of the RCI items, the validity of the data obtained with the RCI based on internal structure, and the reliability of the data obtained with the RCI. Classical test theory (CTT) was utilized to determine the quality of the items. To gather validity evidence, the Rasch model was used and a differential item functioning (DIF) analysis was conducted. Reliability estimates were made using McDonald's Omega. Since validity and reliability evidence was gathered for the assessment scores, the data obtained in this study supports the use of the 14-item RCI for detecting student alternate conceptions with resonance.

共振是有机化学的一个重要而基本的主题,许多本科化学学生对共振有不同的概念。为了帮助解决这些替代概念,有机化学教师可以管理共振概念清单(RCI),这是一项多项选择评估,旨在识别有机化学学生持有的与共振相关的替代概念。在本研究中,对有机化学本科学生进行了两次RCI测试:RCI- pilot (N = 484)和RCI- final (N = 595)。收集证据来支持RCI项目的质量、基于内部结构的RCI获得的数据的效度以及RCI获得的数据的信度。采用经典测试理论(CTT)来确定项目的质量。为了收集效度证据,我们使用了Rasch模型,并进行了差异项目功能(DIF)分析。可靠性估计是用麦当劳的Omega来做的。由于对评估分数收集了效度和信度证据,本研究获得的数据支持使用14项RCI来检测学生的共振替代概念。
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引用次数: 0
A systematic review of green and sustainable chemistry training research with pedagogical content knowledge framework: current trends and future directions 基于教学内容知识框架的绿色与可持续化学训练研究:当前趋势与未来方向
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-10-29 DOI: 10.1039/D4RP00166D
Sevgi Aydin Gunbatar, Betul Ekiz Kiran, Yezdan Boz and Elif Selcan Oztay

This study reviewed the green and sustainable chemistry education (GSCE) research that provided training at the tertiary level from 2000 to 2024. The Web of Science and ERIC databases were screened using title and abstract review. In total, 49 studies were analysed. The analysis instrument has two main parts, namely, general characteristics of the training, which was formed in light of the GSCE literature (i.e., chemistry sub-disciplines, type of implementation, and context), and analysis of the training through the lens of pedagogical content knowledge (PCK) construct that is the commonly-used framework for the analysis of training regarding orientation to teaching GSCE, learner, curriculum, assessment, and instructional strategies utilised. Results showed that organic chemistry (n = 15) is the most emphasised branch of chemistry in the articles. Regarding the learner component, the studies were inadequate, and very few studies provided information about the misconceptions and difficulties that students may encounter while learning GSC. Regarding the curriculum component, among the green chemistry principles, ‘use of renewable feedstocks’ was the most emphasised, while the least emphasised ones were ‘reduce derivatives’ and ‘real-time pollution prevention’. Fourteen studies used subject-specific teaching strategies (e.g., cooperative teaching and project-based strategies). Although representations are not used in GSCE, most of the studies included laboratory studies (n = 31). Finally, regarding the assessment, very few studies focused on measuring students' skills (laboratory skills, discussion skills, etc.) and affective variables. In light of the findings, GSCE training should get more benefit from the literature on science/chemistry teaching strategies. Moreover, alternative assessment tools (e.g., rubrics and concept maps) should be utilized regarding the instruments utilized to assess the participants' GSC knowledge.

本文回顾了2000年至2024年绿色与可持续化学教育(GSCE)在高等教育培训中的研究。Web of Science和ERIC数据库采用标题和摘要综述的方法进行筛选。总共分析了49项研究。分析工具有两个主要部分,即培训的一般特征,这是根据GSCE文献(即化学子学科,实施类型和背景)形成的,以及通过教学内容知识(PCK)结构的视角对培训进行分析,PCK是分析GSCE教学方向,学习者,课程,评估和使用的教学策略的常用框架。结果表明,有机化学(n = 15)是文章中最强调的化学分支。关于学习者部分,研究是不充分的,很少有研究提供关于学生在学习GSC时可能遇到的误解和困难的信息。就课程内容而言,在绿色化学原则中,“使用可再生原料”被强调最多,而“减少衍生物”和“实时污染预防”被强调最少。14项研究使用了特定学科的教学策略(例如,合作教学和基于项目的策略)。虽然在GSCE中没有使用陈述,但大多数研究都包括实验室研究(n = 31)。最后,在评估方面,很少有研究关注于测量学生的技能(实验技能、讨论技能等)和情感变量。根据研究结果,GSCE培训应该更多地受益于科学/化学教学策略方面的文献。此外,对于用于评估参与者的GSC知识的工具,应该使用替代评估工具(例如,规则和概念图)。
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引用次数: 0
Contribution of an instructional module incorporating PhET simulations to Rwandan students' knowledge of chemical reactions, acids, and bases through social interactions 结合PhET模拟的教学模块的贡献,使卢旺达学生通过社会互动了解化学反应、酸和碱
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-10-29 DOI: 10.1039/D4RP00105B
Jean-Baptiste Ndagijimana, Jeannette Musengimana, Henriette Mushimiyimana, Evode Mukama, Olivier Habimana, Paulin Manirakiza, Jean Claude Dushimimana, Jean Pierre Alpha Munyaruhengeri, Samia Khan and Elizabeth Lakin

The current study ascertained the influence an instructional module had on enhancing students’ understanding of chemical reactions and acid–base topics. The sample size for this study consisted of 197 students, including 101 in an “experimental” group and 96 in a “control” group, selected from schools in two Districts (Rwamagana and Musanze) in Rwanda, Africa. The experimental and control groups received a pre-test and post-test to collect data. In addition, focus group discussions (FGDs) were conducted with students in the experimental group. Further, a test question analysis was used to evaluate the students’ content knowledge of chemical reactions and acids, bases, and pH. To analyze the research data, the Statistical Package for the Social Sciences (SPSS) software was used for quantitative analysis. The independent t-test results indicated no significant difference between the means of the control and experimental groups at the pre-test stage (df = 195, p = 0.380). At the post-test stage, a statistically significant increase was observed in the mean scores of the experimental group compared to the control group (df = 195, p < 0.001), showing that the intervention effectively improved student learning outcomes in chemistry education.

本研究确定了教学模块对提高学生对化学反应和酸碱主题的理解的影响。本研究的样本量包括197名学生,其中101名为“实验组”,96名为“对照组”,他们选自非洲卢旺达两个地区(鲁瓦马加纳和穆桑泽)的学校。实验组和对照组分别进行前测和后测,收集数据。此外,与实验组学生进行焦点小组讨论(fgd)。进一步,采用试题分析法评估学生对化学反应和酸、碱、ph的内容知识。对研究数据进行分析时,采用SPSS软件进行定量分析。独立t检验结果显示,对照组和实验组的均值在检验前阶段无显著差异(df = 195, p = 0.380)。在测试后阶段,实验组的平均得分较对照组有统计学意义的升高(df = 195, p <;0.001),表明干预有效地改善了学生在化学教育中的学习成果。
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引用次数: 0
“It is not just the shape, there is more”: students’ learning of enzyme–substrate interactions with immersive Virtual Reality “不仅仅是形状,还有更多”:学生通过沉浸式虚拟现实学习酶-底物相互作用
IF 2.6 2区 教育学 Q1 EDUCATION & EDUCATIONAL RESEARCH Pub Date : 2024-10-29 DOI: 10.1039/D4RP00210E
Henry Matovu, Mihye Won, Roy Tasker, Mauro Mocerino, David Franklin Treagust, Dewi Ayu Kencana Ungu and Chin-Chung Tsai

Immersive Virtual Reality (iVR) can help students visualise and explore complex chemical concepts, such as protein enzyme structures and interactions. We designed a set of collaborative iVR-based learning tasks on the interaction between a protein enzyme and its substrate. We investigated how 18 pairs (36 students) in undergraduate chemistry courses changed their understanding of enzyme–substrate interactions through iVR learning tasks. Videos of pre- and post-interviews and student-generated diagrams were analysed. Before iVR, students had abstract models of the structure of a protein enzyme or its interaction with a substrate molecule. Over 90 per cent of the students (33/36) explained enzyme–substrate interactions using simplistic lock-and-key diagrams, exclusively focusing on the shape. Although many students employed key scientific terms like activation energy in their explanations, they were unsure how enzymes lowered activation energy or how catalytic reactions occurred. After iVR, all students discussed the inadequacy of 2D diagrams for representing complex enzyme–substrate interactions. About 90 per cent of students (32/36) used concrete ideas such as electron density and orientation of reactants in the active site to explain the probability of successful interactions between the enzyme and its substrate. Our findings provide evidence of how interactive iVR learning tasks can help students explore complex molecular structures, integrate ideas, and build a concrete understanding of challenging science concepts.

沉浸式虚拟现实(iVR)可以帮助学生可视化和探索复杂的化学概念,如蛋白质酶结构和相互作用。我们设计了一套基于协作性ivr的学习任务,用于研究蛋白质酶与其底物之间的相互作用。我们调查了18对(36名学生)本科化学课程如何通过iVR学习任务改变他们对酶-底物相互作用的理解。分析了访谈前后的视频和学生生成的图表。在iVR之前,学生们有一个蛋白质酶的结构或它与底物分子相互作用的抽象模型。超过90%的学生(33/36)使用简单的锁与钥匙图解释酶与底物的相互作用,只关注形状。尽管许多学生在解释时使用了活化能等关键科学术语,但他们不确定酶是如何降低活化能的,也不确定催化反应是如何发生的。在iVR之后,所有学生都讨论了2D图在表示复杂的酶-底物相互作用方面的不足。大约90%的学生(32/36)使用具体的概念,如活性位点的电子密度和反应物的方向,来解释酶和底物之间成功相互作用的可能性。我们的研究结果提供了交互式iVR学习任务如何帮助学生探索复杂的分子结构,整合思想,并对具有挑战性的科学概念建立具体理解的证据。
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引用次数: 0
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