Pub Date : 1993-10-31DOI: 10.1109/ULTSYM.1993.339634
P. Carson, Xu Li Xu Li, J. Pallister, A. Moskalik, J. Rubin, J. Fowlkes
Ultrasound systems have been quite limited in the degree to which they facilitate quantification of reasonably available detected mean tumor flow characteristics such as: detected fractional blood volume, B v; speed-weighted, detected fractional blood volume, Bvv and mean speed of regionally-detected blood flow, v¯. This lack of quantification follows from the relative disinterest in such quantitative imaging as well as the dependence of any backscattered signal levels on intervening tissues and physical barriers to discrimination of the very slow flow and weak scattering amplitude of the dominant (capillary) blood pool relative to the soft tissue motion and scattering level, respectively. However, new signal power imaging modes offer some of the necessary data for measures such as Bv. Some color flow imaging systems also now offer improved clutter cancellers, sharper high pass filters, and other flexibility in adjustments for low speed flow. In addition, intravenous contrast agents will soon become available. Doing the best that is reasonably possible to quantify observed flow characteristics should aid objective assessment of the potential role of color flow and power mode ultrasound in utilizing the high metabolic rate of most breast cancers and metastases. Examples on a benign breast mass are presented
{"title":"Approximate quantification of detected fractional blood volume and perfusion from 3-D color flow and Doppler power signal imaging","authors":"P. Carson, Xu Li Xu Li, J. Pallister, A. Moskalik, J. Rubin, J. Fowlkes","doi":"10.1109/ULTSYM.1993.339634","DOIUrl":"https://doi.org/10.1109/ULTSYM.1993.339634","url":null,"abstract":"Ultrasound systems have been quite limited in the degree to which they facilitate quantification of reasonably available detected mean tumor flow characteristics such as: detected fractional blood volume, B v; speed-weighted, detected fractional blood volume, Bvv and mean speed of regionally-detected blood flow, v¯. This lack of quantification follows from the relative disinterest in such quantitative imaging as well as the dependence of any backscattered signal levels on intervening tissues and physical barriers to discrimination of the very slow flow and weak scattering amplitude of the dominant (capillary) blood pool relative to the soft tissue motion and scattering level, respectively. However, new signal power imaging modes offer some of the necessary data for measures such as Bv. Some color flow imaging systems also now offer improved clutter cancellers, sharper high pass filters, and other flexibility in adjustments for low speed flow. In addition, intravenous contrast agents will soon become available. Doing the best that is reasonably possible to quantify observed flow characteristics should aid objective assessment of the potential role of color flow and power mode ultrasound in utilizing the high metabolic rate of most breast cancers and metastases. Examples on a benign breast mass are presented","PeriodicalId":127770,"journal":{"name":"1993 Proceedings IEEE Ultrasonics Symposium","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127206922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-10-31DOI: 10.1109/ULTSYM.1993.339631
K. Parker, S. Huang, R. Lerner, F. Lee, D. Rubens, D. Roach
Although ultrasound imaging of the prostate continues to attract increasing clinical attention, little has been published on the fundamental ultrasound properties of normal and abnormal prostates. This report provides data on ultrasound properties of whole canine and human prostate specimens, and also the results of measurements of elastic properties of whole organs. The high frequency (ultrasound) properties are germane to B-scan imaging of the prostate, whereas the low frequency (elastic) properties are germane to the perceived “stiffness” of the organ during palpation. The two domains of high frequency (MHz ultrasound imaging) and low frequency (elastic constants) have recently been coupled by a novel technique called "sonoelasticity imaging" and understanding of the basic properties is required for successful development of sonoelastic techniques
{"title":"Elastic and ultrasonic properties of the prostate","authors":"K. Parker, S. Huang, R. Lerner, F. Lee, D. Rubens, D. Roach","doi":"10.1109/ULTSYM.1993.339631","DOIUrl":"https://doi.org/10.1109/ULTSYM.1993.339631","url":null,"abstract":"Although ultrasound imaging of the prostate continues to attract increasing clinical attention, little has been published on the fundamental ultrasound properties of normal and abnormal prostates. This report provides data on ultrasound properties of whole canine and human prostate specimens, and also the results of measurements of elastic properties of whole organs. The high frequency (ultrasound) properties are germane to B-scan imaging of the prostate, whereas the low frequency (elastic) properties are germane to the perceived “stiffness” of the organ during palpation. The two domains of high frequency (MHz ultrasound imaging) and low frequency (elastic constants) have recently been coupled by a novel technique called \"sonoelasticity imaging\" and understanding of the basic properties is required for successful development of sonoelastic techniques","PeriodicalId":127770,"journal":{"name":"1993 Proceedings IEEE Ultrasonics Symposium","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132837520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-10-31DOI: 10.1109/ULTSYM.1993.339473
J. Andle, J. T. Weaver, J. Vetelino, D. McAllister
One of the most important issues in acoustic plate mode (APM) sensor design has been the excitation of a single acoustic mode within the APM spectrum. In order to acheive this selective excitation without incurring high triple transit distortions, single phase unidirectional transducers (SPUDT) are employed. Thick aluminum electrodes are used to provide strong mechanical reflections and improve the directivity, hence the phase linearity, of the resulting delay line. A dual delay line oscillator (DDLO) sensor measurement system has been evaluated for the selective detection of double-stranded DNA. The observed frequency shifts indicate an essentially linear, reproducible response to chemically denatured DNA samples up to at least 200 ng/mL. The observed fractional frequency change per unit mass (1/f δF/δm) is -6×10-8 ng-1 of DNA in a 1 mL solution.
声板模式(APM)传感器设计中最重要的问题之一是在APM频谱内激发单个声模式。为了实现这种选择性激励而不产生高的三次传输畸变，采用了单相单向换能器(SPUDT)。厚铝电极用于提供强的机械反射，并改善延迟线的指向性，从而提高相位线性度。研究了双延迟线振荡器(dddlo)传感器测量系统在双链DNA选择性检测中的应用。观察到的频移表明，对化学变性DNA样品的响应至少为200ng /mL，基本上是线性的，可重复的。在1ml溶液中，每单位质量(1/f δ f /δm)观察到的分数频率变化是-6倍于10-8 ng-1的DNA。
{"title":"Application of unidirectional transducers in acoustic plate mode biosensors","authors":"J. Andle, J. T. Weaver, J. Vetelino, D. McAllister","doi":"10.1109/ULTSYM.1993.339473","DOIUrl":"https://doi.org/10.1109/ULTSYM.1993.339473","url":null,"abstract":"One of the most important issues in acoustic plate mode (APM) sensor design has been the excitation of a single acoustic mode within the APM spectrum. In order to acheive this selective excitation without incurring high triple transit distortions, single phase unidirectional transducers (SPUDT) are employed. Thick aluminum electrodes are used to provide strong mechanical reflections and improve the directivity, hence the phase linearity, of the resulting delay line. A dual delay line oscillator (DDLO) sensor measurement system has been evaluated for the selective detection of double-stranded DNA. The observed frequency shifts indicate an essentially linear, reproducible response to chemically denatured DNA samples up to at least 200 ng/mL. The observed fractional frequency change per unit mass (1/f δF/δm) is -6×10-8 ng-1 of DNA in a 1 mL solution.","PeriodicalId":127770,"journal":{"name":"1993 Proceedings IEEE Ultrasonics Symposium","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124312162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1993-10-31DOI: 10.1109/ULTSYM.1993.339712
T. Nagatsuka, K. Misu, T. Kimura, S. Wadaka, A. Sakai, T. Mizuguchi
Thousands of taps with small weights are required for IDTs to achieve narrow transition bandwidths in SAW filters used for satellite applications, In this paper, withdrawal weighting for IDTs is employed to eliminate diffraction problems encountered in overlap weighting. To obtain a good approximation, an original weighting function is decomposed into two functions such that the number of small weights decreases. In the decomposition procedure, the so called zero separation method is applied to the sampled original weighting function, because it is difficult to calculate zeros of thousand order polynomials. The decomposed functions are interpolated, and then approximated by withdrawal weighting. The resultant two weighting functions are applied to input and output IDTs respectively
{"title":"A narrow transition bandwidth SAW filter using withdrawal weighting with decomposed weighting functions","authors":"T. Nagatsuka, K. Misu, T. Kimura, S. Wadaka, A. Sakai, T. Mizuguchi","doi":"10.1109/ULTSYM.1993.339712","DOIUrl":"https://doi.org/10.1109/ULTSYM.1993.339712","url":null,"abstract":"Thousands of taps with small weights are required for IDTs to achieve narrow transition bandwidths in SAW filters used for satellite applications, In this paper, withdrawal weighting for IDTs is employed to eliminate diffraction problems encountered in overlap weighting. To obtain a good approximation, an original weighting function is decomposed into two functions such that the number of small weights decreases. In the decomposition procedure, the so called zero separation method is applied to the sampled original weighting function, because it is difficult to calculate zeros of thousand order polynomials. The decomposed functions are interpolated, and then approximated by withdrawal weighting. The resultant two weighting functions are applied to input and output IDTs respectively","PeriodicalId":127770,"journal":{"name":"1993 Proceedings IEEE Ultrasonics Symposium","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132491504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：