Mildred Cecilia Armenteros Torres, R. Quintanilla, Elizabeth Montes de Oca Megias, Vivianne ne Anido Escobar, N. Contino
Introduction: Barrett's esophagus (BE) with low-grade dysplasia represents a risk of progression towards esophageal adenocarcinoma. Hybrid-APC turns out to be an effective, safe, easy to use and relatively low-cost technique to stop this progression. Aims: to describe the therapeutic response of Hybrid-APC in patients with low-grade dysplasia in Barrett's esophagus. Method: an observational, descriptive investigation of a series of cases was carried out at the National Center for Minimal Access Surgery between December 2018 and December 2020. Twenty patients with BE histologically classified with low-grade dysplasia were included. Ablation with Hybrid APC was applied, and endoscopy was performed three and six months after the end of the treatment. The therapeutic response was evaluated through histological remission and the presence of complications. The information was processed in the statistical program SPSS, version 21. Results: mean age 50.5 (range 27-81 years). 55% (11) are male. Eighty-five percent were asymptomatic and 90% had circumferential BE. 55% (11) required a HybridAPC session. With an average of 1.4 sessions, macroscopic and histological remission without dysplasia was achieved at three and six months in 90% (18/20) and 92.8% (13/14) of the patients respectively, without witnessing complications. Conclusions: endoscopic treatment with the Hybrid-APC has a good therapeutic response, with a good histological remission and without complications, in patients with low-grade dysplasia in BE.
{"title":"Treatment of Barrett's esophagus with low-grade dysplasia using Hibrid-APC","authors":"Mildred Cecilia Armenteros Torres, R. Quintanilla, Elizabeth Montes de Oca Megias, Vivianne ne Anido Escobar, N. Contino","doi":"10.33425/2833-4418.0001","DOIUrl":"https://doi.org/10.33425/2833-4418.0001","url":null,"abstract":"Introduction: Barrett's esophagus (BE) with low-grade dysplasia represents a risk of progression towards esophageal adenocarcinoma. Hybrid-APC turns out to be an effective, safe, easy to use and relatively low-cost technique to stop this progression. Aims: to describe the therapeutic response of Hybrid-APC in patients with low-grade dysplasia in Barrett's esophagus. Method: an observational, descriptive investigation of a series of cases was carried out at the National Center for Minimal Access Surgery between December 2018 and December 2020. Twenty patients with BE histologically classified with low-grade dysplasia were included. Ablation with Hybrid APC was applied, and endoscopy was performed three and six months after the end of the treatment. The therapeutic response was evaluated through histological remission and the presence of complications. The information was processed in the statistical program SPSS, version 21. Results: mean age 50.5 (range 27-81 years). 55% (11) are male. Eighty-five percent were asymptomatic and 90% had circumferential BE. 55% (11) required a HybridAPC session. With an average of 1.4 sessions, macroscopic and histological remission without dysplasia was achieved at three and six months in 90% (18/20) and 92.8% (13/14) of the patients respectively, without witnessing complications. Conclusions: endoscopic treatment with the Hybrid-APC has a good therapeutic response, with a good histological remission and without complications, in patients with low-grade dysplasia in BE.","PeriodicalId":130129,"journal":{"name":"Gastroenterology Hepatology and Digestive System","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122362098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current issues in hepatitis E: an overview","authors":"P. Mohammad K.","doi":"10.33425/2833-4418.0003","DOIUrl":"https://doi.org/10.33425/2833-4418.0003","url":null,"abstract":"","PeriodicalId":130129,"journal":{"name":"Gastroenterology Hepatology and Digestive System","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129532359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. J. Aurelus, Rafael Roberto Zapata Carrión, Sandra Karina Diaz Cardona, Sofía Brenes Guzmán, María Del Sol Granados Alonso, Ramón Eduardo Salgado Sangri, Hermilo De La Cruz Yáñez
Introduction: Portal hypertension is the main cause of morbidity and mortality in infant diagnosed of biliary atresia (BA) and cavernous deformation of the portal vein. Portal hypertension evolves as a result of increased intrahepatic vascular resistance, most commonly caused by a chronic liver disease. The clinical manifestations are ascites and bleeding owing the esophageal and gastric varices. The mortality rate per acute episode of bleeding is 5% to 19% in children. The aim of this work was to evaluate the clinical influence of rebleeding, refractory ascites, child-Pugh class (C.P) and shunt patency in infant underwent spleno-pancreatorenal (SPR) shunt in a case series in a pediatric reference medical center. Patients and Methods: Retrospective and observational work was performed owing clinical surveillance of C.P, shunt patency, rebleeding and ascites formation after SPR shunt procedure from December 2017 to November 2020. Of 16 shunts performed in this period, 3(18.7%) patients had SPR shunt. The three patients were females and the mean weight was 6.5kg. Outcomes and Results: The search identified three patients underwent surgical shunts of SPR less than 2-year-old. All of three patients had shunt patency in the first three months from the procedure. One patient had thrombosis of the shunt at fourth month from the operation. The three patients had improvement in the C.P class, 1 patient had infectious, rebleeding and ascites between 4 months from the procedure. Conclusion: The three patients had no experienced shunt complications in the first three months from the procedure.
{"title":"Patency of spleno-pancreatorenal shunt in infant with portal hypertension, case series and literature review","authors":"P. J. Aurelus, Rafael Roberto Zapata Carrión, Sandra Karina Diaz Cardona, Sofía Brenes Guzmán, María Del Sol Granados Alonso, Ramón Eduardo Salgado Sangri, Hermilo De La Cruz Yáñez","doi":"10.33425/2833-4418.0002","DOIUrl":"https://doi.org/10.33425/2833-4418.0002","url":null,"abstract":"Introduction: Portal hypertension is the main cause of morbidity and mortality in infant diagnosed of biliary atresia (BA) and cavernous deformation of the portal vein. Portal hypertension evolves as a result of increased intrahepatic vascular resistance, most commonly caused by a chronic liver disease. The clinical manifestations are ascites and bleeding owing the esophageal and gastric varices. The mortality rate per acute episode of bleeding is 5% to 19% in children. The aim of this work was to evaluate the clinical influence of rebleeding, refractory ascites, child-Pugh class (C.P) and shunt patency in infant underwent spleno-pancreatorenal (SPR) shunt in a case series in a pediatric reference medical center. Patients and Methods: Retrospective and observational work was performed owing clinical surveillance of C.P, shunt patency, rebleeding and ascites formation after SPR shunt procedure from December 2017 to November 2020. Of 16 shunts performed in this period, 3(18.7%) patients had SPR shunt. The three patients were females and the mean weight was 6.5kg. Outcomes and Results: The search identified three patients underwent surgical shunts of SPR less than 2-year-old. All of three patients had shunt patency in the first three months from the procedure. One patient had thrombosis of the shunt at fourth month from the operation. The three patients had improvement in the C.P class, 1 patient had infectious, rebleeding and ascites between 4 months from the procedure. Conclusion: The three patients had no experienced shunt complications in the first three months from the procedure.","PeriodicalId":130129,"journal":{"name":"Gastroenterology Hepatology and Digestive System","volume":"75 Suppl 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130805150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complicated Crohn’s disease: An unusual destination of an enterocutaneous fistula","authors":"Emran Alali, R. Bosio, T. Alhmoud","doi":"10.33425/2833-4418.0004","DOIUrl":"https://doi.org/10.33425/2833-4418.0004","url":null,"abstract":"","PeriodicalId":130129,"journal":{"name":"Gastroenterology Hepatology and Digestive System","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123569248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Letícia Mocellin, Eduarda Paitl Agostinho, Vinicius beck da Silveira, M. Gonçalves, João Alfredo Diedrich Neto
Introduction: Neuroendocrine tumors, also called neuroendocrine carcinomas, are those that form in any region of the neuroendocrine system. Although they are more common in the gastrointestinal tract (67.5%), their appearance in the esophagus is rare. Another important characteristic is its slow growth and low degree of aggressiveness. Case report: A46-year-old male patient, seeking care for progressive phagia for solidspathstenoses digestive endoscopy that showed the diagnosis of distal esophagus whose anatomoological and immunohistochemical was of a neuroendocrine esophageal tumor. Subjected to staging, there were numerous liver metastases and lymph node enlargement of the celiac trunk, and palliative treatment was chosen. The patient had an unfavorable evolution, progressing to jaundice, ascites, worsening of general condition, progressed to death in about 3 months after diagnosis. Discussion: The incidence and prevalence of neuroendocrine esophageal tumor has been increasing since 1970 due to the modernization of diagnostic techniques. Despite the increase in diagnostic capacity, this pathology remains rare, corresponding to 0.15% - 2.80% of esophageal carcinomas. The median survival time for patients with this neoplasm is 22.4 months, having a totally different evolution from other neuroendocrine tumors of the digestive tract..
{"title":"Esophageal Neuroendocrine Tumor: Case Report","authors":"Letícia Mocellin, Eduarda Paitl Agostinho, Vinicius beck da Silveira, M. Gonçalves, João Alfredo Diedrich Neto","doi":"10.33425/2833-4418.0005","DOIUrl":"https://doi.org/10.33425/2833-4418.0005","url":null,"abstract":"Introduction: Neuroendocrine tumors, also called neuroendocrine carcinomas, are those that form in any region of the neuroendocrine system. Although they are more common in the gastrointestinal tract (67.5%), their appearance in the esophagus is rare. Another important characteristic is its slow growth and low degree of aggressiveness. Case report: A46-year-old male patient, seeking care for progressive phagia for solidspathstenoses digestive endoscopy that showed the diagnosis of distal esophagus whose anatomoological and immunohistochemical was of a neuroendocrine esophageal tumor. Subjected to staging, there were numerous liver metastases and lymph node enlargement of the celiac trunk, and palliative treatment was chosen. The patient had an unfavorable evolution, progressing to jaundice, ascites, worsening of general condition, progressed to death in about 3 months after diagnosis. Discussion: The incidence and prevalence of neuroendocrine esophageal tumor has been increasing since 1970 due to the modernization of diagnostic techniques. Despite the increase in diagnostic capacity, this pathology remains rare, corresponding to 0.15% - 2.80% of esophageal carcinomas. The median survival time for patients with this neoplasm is 22.4 months, having a totally different evolution from other neuroendocrine tumors of the digestive tract..","PeriodicalId":130129,"journal":{"name":"Gastroenterology Hepatology and Digestive System","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131425503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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