首页 > 最新文献

International Journal of Applied Research in Natural Products最新文献

英文 中文
Good Agricultural Practice (GAP) -Does It Ensure a Perfect Supply of Medicinal Herbs for Research and Drug Development? 良好农业规范(GAP)——它能确保用于研究和药物开发的药材的完美供应吗?
Pub Date : 2008-06-15 DOI: 10.1142/9789812774019_0003
P. Leung, K. Cheng
Summary: While users of herbal formulae have been disappointed with the lack of uniformity with the quality of herbs provided by the herb suppliers of different standings, they do not have better means of supply.  The tradition of identifying special geographic regions, as being specific for the best supply of certain herbal items is no longer reliable since the large demand for large quantities of quality supply could not be satisfied by limited plantations in those regions. A comprehensive recommendation of agricultural practice: from seedling, planting, fertilizing, harvesting, storage to distribution, can be offered as a compromise.  There is good prospect of an excellent supply of quality herbal products with uniformity, if Good Agricultural Practice (GAP) could be practiced and enforced. Although the need for GAP is urgent, and Japan, China and World Health Organization, have one after the other, written up their recommendation, to put GAP into real practice would need special efforts and takes time. GAP in China is particularly difficult, not only because the herbal items involved are of great numbers but because the current practice of growing medicinal herbs, their marketing and distribution, have been counterproductive to the introduction of the new system of GAP. At this stage, GAP will not be able to satisfy the extensive need for quality and uniformity.  Short of the knowledge of the exact, accurate nature of the active components within a herb, there will be no perfect guarantee on the quality supply.  Henceforth, even when GAP becomes a mature practice, what is required for quality control, viz, different levels of authentication, from chemical finger printing to molecular, DNA identification, will remain necessary as cross-checking mechanisms to make sure that uniformity in scientific experiments and drug development could be maintained
摘要:虽然草药配方的使用者对不同等级的草药供应商提供的草药质量缺乏一致性感到失望,但他们没有更好的供应方式。确定特定地理区域作为某些草药的最佳供应地点的传统已不再可靠,因为这些区域的有限种植无法满足对大量优质供应的大量需求。一个综合的农业实践建议:从种苗、种植、施肥、收获、储存到分配,可以作为一个折衷方案。如果良好农业规范(GAP)能够得到实施和执行,将有良好的前景提供质量统一的优质草药产品。尽管对GAP的需求十分迫切,日本、中国和世界卫生组织也相继提出了建议,但要真正实施GAP还需要特别的努力和时间。GAP在中国尤其困难,不仅因为所涉及的草药项目数量庞大,而且因为目前种植草药的做法,他们的营销和分销,已经对GAP新系统的引入产生了反作用。在这个阶段,GAP将无法满足对质量和均匀性的广泛需求。缺乏对草药中有效成分的确切、准确性质的了解,就没有质量供应的完美保证。因此,即使GAP成为一种成熟的做法,质量控制所需要的,即不同层次的认证,从化学指纹到分子,DNA鉴定,仍然是必要的,作为交叉检查机制,以确保科学实验和药物开发的统一性
{"title":"Good Agricultural Practice (GAP) -Does It Ensure a Perfect Supply of Medicinal Herbs for Research and Drug Development?","authors":"P. Leung, K. Cheng","doi":"10.1142/9789812774019_0003","DOIUrl":"https://doi.org/10.1142/9789812774019_0003","url":null,"abstract":"Summary: While users of herbal formulae have been disappointed with the lack of uniformity with the quality of herbs provided by the herb suppliers of different standings, they do not have better means of supply.  The tradition of identifying special geographic regions, as being specific for the best supply of certain herbal items is no longer reliable since the large demand for large quantities of quality supply could not be satisfied by limited plantations in those regions. A comprehensive recommendation of agricultural practice: from seedling, planting, fertilizing, harvesting, storage to distribution, can be offered as a compromise.  There is good prospect of an excellent supply of quality herbal products with uniformity, if Good Agricultural Practice (GAP) could be practiced and enforced. Although the need for GAP is urgent, and Japan, China and World Health Organization, have one after the other, written up their recommendation, to put GAP into real practice would need special efforts and takes time. GAP in China is particularly difficult, not only because the herbal items involved are of great numbers but because the current practice of growing medicinal herbs, their marketing and distribution, have been counterproductive to the introduction of the new system of GAP. At this stage, GAP will not be able to satisfy the extensive need for quality and uniformity.  Short of the knowledge of the exact, accurate nature of the active components within a herb, there will be no perfect guarantee on the quality supply.  Henceforth, even when GAP becomes a mature practice, what is required for quality control, viz, different levels of authentication, from chemical finger printing to molecular, DNA identification, will remain necessary as cross-checking mechanisms to make sure that uniformity in scientific experiments and drug development could be maintained","PeriodicalId":13805,"journal":{"name":"International Journal of Applied Research in Natural Products","volume":"21 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2008-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86330970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
期刊
International Journal of Applied Research in Natural Products
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1