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A case of transient right ventricular failure secondary to severe pulmonary hypertension in setting of methamphetamine use 甲基苯丙胺使用后继发于严重肺动脉高压的短暂性右心室衰竭1例
Pub Date : 2022-09-20 DOI: 10.5348/100013c03pk2022cr
P. Kaur, Syed S. Fatmi, Sidra Shakil, Saikiran Mandyam, Bsmah Abdalslam
Methamphetamine has been documented to be associated with pulmonary hypertension. Past studies have shown the association of methamphetamine abuse with pulmonary hypertension; however, cases of isolated acute to subacute right heart failure secondary to methamphetamine use have not been documented. Acute to subacute right heart failure, secondary to methamphetamine use itself represents a diagnostic challenge as there is no specific protocol in place for evaluation for pulmonary hypertension secondary to methamphetamine use and high degree of suspicion is needed to differentiate it from other cardio-pulmonary conditions. Echocardiographic findings of increased right ventricular systolic pressure along with morphological findings suggesting cardiac remodeling in the setting of methamphetamine use is highly suspicious of acute to subacute right heart failure. Early recognition and management, along with long-term abstinence from methamphetamine use is critical to prevent chronic effects on myocardium and to prevent further cardiac remodeling. Although dedicated cardiothoracic imaging and cardiac catheterization can be beneficial; neither of these modalities are needed to establish the diagnosis and to initiate primary interventions. Computed tomography (CT) scan however would be beneficial in excluding other causes of pulmonary hypertension, such as primary pulmonary conditions and pulmonary embolism.
甲基苯丙胺已被证实与肺动脉高压有关。过去的研究表明,甲基苯丙胺滥用与肺动脉高压有关;然而,孤立的急性至亚急性右心衰继发于甲基苯丙胺的病例尚未被记录。甲基苯丙胺使用引起的急性至亚急性右心衰本身是一项诊断挑战,因为目前尚无评估甲基苯丙胺使用引起的肺动脉高压的具体方案,需要高度怀疑才能将其与其他心肺疾病区分开来。超声心动图结果显示右心室收缩压升高以及形态学结果提示甲基苯丙胺使用背景下的心脏重构,高度怀疑急性至亚急性右心衰。早期识别和管理,以及长期戒除甲基苯丙胺的使用对于防止心肌的慢性影响和防止进一步的心脏重塑至关重要。虽然专门的心胸造影和心导管检查是有益的;这两种方式都不需要用于诊断和启动初级干预措施。然而,计算机断层扫描(CT)有助于排除肺动脉高压的其他原因,如原发性肺部疾病和肺栓塞。
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引用次数: 0
Tricky papillary muscle rupture sequelae navigated by evidence-based therapies using ECMO and Impella 棘手的乳头肌破裂后遗症导航循证治疗使用ECMO和Impella
Pub Date : 2022-06-16 DOI: 10.5348/100012c03cs2022cr
Christine Sykalo, M. Herrera, A. Adams, U. Egolum
This case illustrates an atypical mitral valve prolapse presentation with superimposed stress of acute respiratory distress syndrome (ARDS) as well as the importance of extracorporeal membrane oxygenation therapy (ECMO) as a bridge to definitive surgical intervention. Switching from venovenous (VV) to venoarterial (VA) ECMO allowed bypass of the pulmonary circulation and provided cardiac support to assist in systemic circulation in the setting of severe mitral regurgitation with mitral valve prolapse. However, VA ECMO increases afterload, thus an Impella was used to offload the left ventricle and provide forward flow. Relying on evidence-based medicine for each modality despite its complexity also optimized this patient’s chance for recovery. Thereby, we demonstrate a complex case of ARDS, mitral valve prolapse secondary to myocardial infarction, and subsequent multiple arrhythmic arrests, where successful VV and VA ECMO resuscitation afforded bridge therapy to definitive surgical management. Our patient showed promising results, and we would like to encourage this strategy to bridge patients requiring surgical intervention.
本病例说明了急性呼吸窘迫综合征(ARDS)叠加应激的非典型二尖瓣脱垂的表现,以及体外膜氧合治疗(ECMO)作为最终手术干预的桥梁的重要性。从静脉静脉(VV)切换到静脉动脉(VA) ECMO允许肺循环旁路,并提供心脏支持,以协助二尖瓣脱垂的严重二尖瓣反流的体循环。然而,VA ECMO增加了后负荷,因此使用Impella来卸载左心室并提供前流。尽管每一种模式都很复杂,但依靠循证医学也优化了该患者康复的机会。因此,我们展示了一个复杂的ARDS病例,二尖瓣脱垂继发于心肌梗死,随后出现多次心律失常,其中成功的VV和VA ECMO复苏为最终的手术治疗提供了桥梁治疗。我们的病人表现出了很好的结果,我们希望鼓励这种策略来治疗需要手术干预的病人。
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引用次数: 0
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Edorium Journal of Cardiology
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