Pub Date : 2023-01-01DOI: 10.33545/26649225.2023.v5.i1a.7
Dr. Seejo George, Dr. Unnikrishnan Thamarassery
Individuals diagnosed with persistent rhinosinusitis accompanied with polyps in the nasal cavity, which is distinguished by the presence of a type 2 immunological signature, frequently experience severe and recurring symptoms. Lower respiratory tract disorders, such as asthma, frequently coexist with other medical illnesses and have comparable underlying physiological mechanisms. Chronic rhinosinusitis with nasal polyps (CRSwNP) accompanied with asthma is distinguished by the presence of eosinophilic infiltration in the affected tissues and elevated levels of immunoglobulin E (IgE) in the immediate environment. From a clinical perspective, the presence of concomitant asthma in individuals with chronic rhinosinusitis with nasal polyps (CRSwNP) is linked to heightened sinonasal symptoms and a worse quality of life. Furthermore, managing this condition by medicinal and surgical interventions poses greater challenges. The coexistence of nasal polyposis with asthma presents challenges in terms of disease management. This comorbidity is associated with higher susceptibility to exacerbations, heightened airway obstruction, and a greater extent of Eosinophilic inflammation. Individuals diagnosed with chronic rhinosinusitis with nasal polyps (CRSwNP) who also have concurrent aspirin-exacerbated respiratory disease (AERD) are a subgroup characterized by the presence of very severe and challenging-to-manage symptoms. Moreover, these patients typically exhibit a high degree of nasal polyp severity. The diagnosis and treatment of respiratory co-morbidities can be greatly aided by the identification and understanding of shared pathophysiology pathways in the lower as well as the upper airways. The compelling justification for developing systemic medicines that precisely target prevalent type 2 inflammatory mechanisms is the systemic inflammatory link that exists among rhinosinusitis that is chronic with polyps in the nasal passages (CRSwNP) and asthma.
{"title":"Medical condition: Persistent rhinosinusitis accompanied by nasal polyps and asthma","authors":"Dr. Seejo George, Dr. Unnikrishnan Thamarassery","doi":"10.33545/26649225.2023.v5.i1a.7","DOIUrl":"https://doi.org/10.33545/26649225.2023.v5.i1a.7","url":null,"abstract":"Individuals diagnosed with persistent rhinosinusitis accompanied with polyps in the nasal cavity, which is distinguished by the presence of a type 2 immunological signature, frequently experience severe and recurring symptoms. Lower respiratory tract disorders, such as asthma, frequently coexist with other medical illnesses and have comparable underlying physiological mechanisms. Chronic rhinosinusitis with nasal polyps (CRSwNP) accompanied with asthma is distinguished by the presence of eosinophilic infiltration in the affected tissues and elevated levels of immunoglobulin E (IgE) in the immediate environment. From a clinical perspective, the presence of concomitant asthma in individuals with chronic rhinosinusitis with nasal polyps (CRSwNP) is linked to heightened sinonasal symptoms and a worse quality of life. Furthermore, managing this condition by medicinal and surgical interventions poses greater challenges. The coexistence of nasal polyposis with asthma presents challenges in terms of disease management. This comorbidity is associated with higher susceptibility to exacerbations, heightened airway obstruction, and a greater extent of Eosinophilic inflammation. Individuals diagnosed with chronic rhinosinusitis with nasal polyps (CRSwNP) who also have concurrent aspirin-exacerbated respiratory disease (AERD) are a subgroup characterized by the presence of very severe and challenging-to-manage symptoms. Moreover, these patients typically exhibit a high degree of nasal polyp severity. The diagnosis and treatment of respiratory co-morbidities can be greatly aided by the identification and understanding of shared pathophysiology pathways in the lower as well as the upper airways. The compelling justification for developing systemic medicines that precisely target prevalent type 2 inflammatory mechanisms is the systemic inflammatory link that exists among rhinosinusitis that is chronic with polyps in the nasal passages (CRSwNP) and asthma.","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134887410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26649225.2021.v3.i1a.6
Gurchand Singh, M. Gupta, Anisha Puri, C. Kaur, Nitin Basavaraja
{"title":"Unilateral fibroepithelial polyp of palatine tonsil- A rare case","authors":"Gurchand Singh, M. Gupta, Anisha Puri, C. Kaur, Nitin Basavaraja","doi":"10.33545/26649225.2021.v3.i1a.6","DOIUrl":"https://doi.org/10.33545/26649225.2021.v3.i1a.6","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126853432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.33545/26649225.2020.v2.i1a.5
Intidhar El Bez, S. Almadani, F. Alghmlas, Mohammed A. Alharbi, R. Tulbah
{"title":"Treatment of juvenile thyrotoxicosis: A review with emphasis on radioiodine treatment","authors":"Intidhar El Bez, S. Almadani, F. Alghmlas, Mohammed A. Alharbi, R. Tulbah","doi":"10.33545/26649225.2020.v2.i1a.5","DOIUrl":"https://doi.org/10.33545/26649225.2020.v2.i1a.5","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122375813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.33545/26649225.2019.v1.i1a.1
I. Boujguenna, S. Elhatimy, S. Belmaachi, Y. Rochdi, H. Nouri, A. Raji, A. Fakhri, H. Rais
{"title":"Parotid ductal carcinoma: About a case","authors":"I. Boujguenna, S. Elhatimy, S. Belmaachi, Y. Rochdi, H. Nouri, A. Raji, A. Fakhri, H. Rais","doi":"10.33545/26649225.2019.v1.i1a.1","DOIUrl":"https://doi.org/10.33545/26649225.2019.v1.i1a.1","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122638661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.33545/26649225.2019.v1.i1a.3
N. George, Shirish Patil, S. Suresh, C. George
{"title":"A rare malignant neuroectodermal tumour in the thyroid gland","authors":"N. George, Shirish Patil, S. Suresh, C. George","doi":"10.33545/26649225.2019.v1.i1a.3","DOIUrl":"https://doi.org/10.33545/26649225.2019.v1.i1a.3","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116470867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.33545/26649225.2019.v1.i1a.4
Chethana R, A. Dehadaray
{"title":"Rare upper esophageal foreign body and a simple trick to remove it","authors":"Chethana R, A. Dehadaray","doi":"10.33545/26649225.2019.v1.i1a.4","DOIUrl":"https://doi.org/10.33545/26649225.2019.v1.i1a.4","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117209235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.33545/26649225.2019.v1.i1a.2
S. Elhatimy, Y. Rochdi, H. Nouri, L. Aderdour, A. Raji
{"title":"Thyroid discharge revealing an Epidermoid carcinoma of the mouth of the Esophage","authors":"S. Elhatimy, Y. Rochdi, H. Nouri, L. Aderdour, A. Raji","doi":"10.33545/26649225.2019.v1.i1a.2","DOIUrl":"https://doi.org/10.33545/26649225.2019.v1.i1a.2","url":null,"abstract":"","PeriodicalId":163183,"journal":{"name":"International Journal of Otolaryngology Sciences","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128904332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：