Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1013
J. Aman, X. Manz, X. Pan, K. Prange, G. Griffith, A. Jongejan, M. Arkani, P. Symersky, C. Dickhoff, C. Jimenez, M. D. de Winther, H. Bogaard
{"title":"Multi-omic Profiling of the Pulmonary Arterial Endothelium Reveals Disturbed Cell Adhesion and Extracellular Matrix Reorganization in Chronic Thromboembolic Pulmonary Hypertension","authors":"J. Aman, X. Manz, X. Pan, K. Prange, G. Griffith, A. Jongejan, M. Arkani, P. Symersky, C. Dickhoff, C. Jimenez, M. D. de Winther, H. Bogaard","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1013","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1013","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128498535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1019
S. Sulstarova, A. Foley, S. Mylvaganam, B. Steinberg, S. Freeman, N. Goldenberg
{"title":"Breakdown of the Apical Spectrin Network Leads to Endothelial Dysfunction and Vascular Stiffening in Pulmonary Arterial Hypertension","authors":"S. Sulstarova, A. Foley, S. Mylvaganam, B. Steinberg, S. Freeman, N. Goldenberg","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1019","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1019","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116157666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1016
I. Essafri, K. Ichimura, K. Stenmark, E. Spiekerkoetter, V. Kheyfets
{"title":"Acute Pressure Overload in the Right Ventricle (RV) Changes the Tortuosity, Orientation, and Hemodynamics of the Microcirculation","authors":"I. Essafri, K. Ichimura, K. Stenmark, E. Spiekerkoetter, V. Kheyfets","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1016","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1016","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128139292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1014
A. Razee, S. Banerjee, J. Hong, R. Saggar, S. Magaki, F. Gregory, S. Umar
{"title":"Cell Type Specific Targeting of Microglial Activation in the Thoracic Spinal Cord as a Novel Therapeutic Strategy for Pulmonary Hypertension and Right Ventricular Failure","authors":"A. Razee, S. Banerjee, J. Hong, R. Saggar, S. Magaki, F. Gregory, S. Umar","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1014","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1014","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122556323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1018
A. Dekan, M. Niihori, J. James, R. Rafikov, O. Rafikova
{"title":"Single-cell Transcriptomics and Machine Learning Approach to Identify Novel Targets to Treat Right Ventricle Hypertrophy","authors":"A. Dekan, M. Niihori, J. James, R. Rafikov, O. Rafikova","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1018","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1018","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122224404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1010
T. Klouda, H. Kim, T. Liu, G. Visner, B. Raby, K. Yuan
{"title":"Pericytes Contribute to the Vascular Remodeling of Pulmonary Hypertension","authors":"T. Klouda, H. Kim, T. Liu, G. Visner, B. Raby, K. Yuan","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1010","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1010","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131199547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1012
J. P. Dignam, C. Perez-Ternero, A. Aubdool, A. Hobbs
{"title":"C-Type Natriuretic Peptide Signalling Attenuates the Development of Pulmonary Hypertension and Right Ventricular Remodelling","authors":"J. P. Dignam, C. Perez-Ternero, A. Aubdool, A. Hobbs","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1012","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1012","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"61 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134363666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1015
J. Dai, Y. Zhao
{"title":"Single-nucleus Transcriptome Profiling Identifies Phenotypic Shift in Capillary Endothelial Subpopulations in Pulmonary Arterial Hypertension","authors":"J. Dai, Y. Zhao","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1015","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1015","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134601394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1011
A. Lawrie, A. Zawia, L. West, N. Arnold, J. Pickworth, H. Turton, A. Thompson, S. Francis
{"title":"Osteoprotegerin Has Distinct Roles in Pulmonary Vascular and Cardiac Remodelling in a Mouse Model of Pulmonary Arterial Hypertension","authors":"A. Lawrie, A. Zawia, L. West, N. Arnold, J. Pickworth, H. Turton, A. Thompson, S. Francis","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1011","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1011","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123551877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1017
M. Niihori, J. James, N. McClain, F. Konecný, R. Rafikov, O. Rafikova
{"title":"Comprehensive Characterization of RV Function in Pulmonary Arterial Hypertension Model With Mitochondrial Dysfunction","authors":"M. Niihori, J. James, N. McClain, F. Konecný, R. Rafikov, O. Rafikova","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1017","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1017","url":null,"abstract":"","PeriodicalId":166030,"journal":{"name":"A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION","volume":"46 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114041461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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