Anwar Saman, Shayan Ayesha, Naseer Hina, M. Azzan, A. Rabia, Shamim Bushra
Hydatid cyst is a zoonotic disease caused by Echinococcus granulosus. It rarely presents in the musculoskeletal system. Primary hydatid disease in paraspinal muscles is very rare. It can be discovered as an incidental finding in radiological imaging. Symptomatic patients are presented with usually symptoms secondary to the compression effect. It can cause dreadful consequences like erosion of adjacent bones, myelopathy, and cauda equine syndrome if left untreated. We present such a case of Primary Paraspinal Cyst with Intraspinal Extension, and its radiological imaging findings, including X-ray, CT scan, and MRI.
{"title":"Primary paraspinal hydatid cyst with intraspinal extension. A rare case report","authors":"Anwar Saman, Shayan Ayesha, Naseer Hina, M. Azzan, A. Rabia, Shamim Bushra","doi":"10.17352/ijrro.000052","DOIUrl":"https://doi.org/10.17352/ijrro.000052","url":null,"abstract":"Hydatid cyst is a zoonotic disease caused by Echinococcus granulosus. It rarely presents in the musculoskeletal system. Primary hydatid disease in paraspinal muscles is very rare. It can be discovered as an incidental finding in radiological imaging. Symptomatic patients are presented with usually symptoms secondary to the compression effect. It can cause dreadful consequences like erosion of adjacent bones, myelopathy, and cauda equine syndrome if left untreated. We present such a case of Primary Paraspinal Cyst with Intraspinal Extension, and its radiological imaging findings, including X-ray, CT scan, and MRI.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"71 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133524645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yüksel İpek, Gözler Tayfun, Bozkurt İlknur, Ulucan Korkut, Tarhan Nevzat
Introduction: The efficiency of psychiatric therapy depends on various factors and drug metabolism is one of them. The liver plays a significant role in drug metabolism through the P450 enzyme systems. However, pharmacogenetics aims to assist clinicians in determining the effectiveness of a particular drug and minimizing potential side effects. Case report: Here, we present a case to demonstrate the potential use of pharmacogenetics in clinical practice. A 33-year-old male patient with a diagnosis of schizophrenia and OCD had symptoms of sexual auditory hallucinations and obsessive images. According to the patient’s pharmacogenetic profile (CYP2D6, CYP2C9, CYP2C19, CYP1A2 and CYP3A4), the medication started by giving Risperidone 8 mg/day and Aripiprazole 5 mg/day. Aripiprazole was continued at 10 mg/day and then 20 mg/day in the presence of clinical findings. Olanzapine 10 mg/day and Sertraline 50 mg/day were given. In addition, 20 sessions of TMS and 20 sessions of tDCS, which are neuromodulation treatments, were applied. Results: The patient in question experienced some improvement and partial remission following a treatment plan based on pharmacogenetic analysis. In summary, pharmacogenetic testing can be a valuable tool in determining an appropriate treatment plan that maximizes clinical improvement while minimizing potential adverse effects associated with medication.
{"title":"Pharmacogenetic application in a patient diagnosed with Schizophrenia and OCD: A case report","authors":"Yüksel İpek, Gözler Tayfun, Bozkurt İlknur, Ulucan Korkut, Tarhan Nevzat","doi":"10.17352/ijrro.000051","DOIUrl":"https://doi.org/10.17352/ijrro.000051","url":null,"abstract":"Introduction: The efficiency of psychiatric therapy depends on various factors and drug metabolism is one of them. The liver plays a significant role in drug metabolism through the P450 enzyme systems. However, pharmacogenetics aims to assist clinicians in determining the effectiveness of a particular drug and minimizing potential side effects. Case report: Here, we present a case to demonstrate the potential use of pharmacogenetics in clinical practice. A 33-year-old male patient with a diagnosis of schizophrenia and OCD had symptoms of sexual auditory hallucinations and obsessive images. According to the patient’s pharmacogenetic profile (CYP2D6, CYP2C9, CYP2C19, CYP1A2 and CYP3A4), the medication started by giving Risperidone 8 mg/day and Aripiprazole 5 mg/day. Aripiprazole was continued at 10 mg/day and then 20 mg/day in the presence of clinical findings. Olanzapine 10 mg/day and Sertraline 50 mg/day were given. In addition, 20 sessions of TMS and 20 sessions of tDCS, which are neuromodulation treatments, were applied. Results: The patient in question experienced some improvement and partial remission following a treatment plan based on pharmacogenetic analysis. In summary, pharmacogenetic testing can be a valuable tool in determining an appropriate treatment plan that maximizes clinical improvement while minimizing potential adverse effects associated with medication.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130093952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burdick Hoyt J, Shoemaker Tina, Godby Nancy, Norweck James
During a routine NRC inspection, a review of historical occupational dosimetry monitoring data for interventional radiology physician AUs was questioned regarding unexpectedly low results. This was interpreted to be an indicator of noncompliance with the wearing of occupational dose monitoring devices and, therefore, required occupation dose reconstructions in order to estimate the actual dose. In an effort to comply with dose monitoring requirements, the AU interventional radiologists diligently began wearing their whole-body and ring dosimeters during all procedures including Y-90, fluoroscopy-guided and CT-guided. In the interest of patient care, an AU that performs many interventional CT-guided procedures involving the use of a cumbersome treatment device, placed his hand in the CT beam on numerous occasions to stabilize the device. This quickly resulted in a cumulative extremity exposure that exceeded allowed limits. Once we became aware of the extremity over-exposure, steps were taken to prevent any further significant extremity exposure for the remainder of the year. The over-exposure was reported to the NRC and State following regulatory requirements.
{"title":"A case of extremity over-exposure and regulatory compliance","authors":"Burdick Hoyt J, Shoemaker Tina, Godby Nancy, Norweck James","doi":"10.17352/ijrro.000050","DOIUrl":"https://doi.org/10.17352/ijrro.000050","url":null,"abstract":"During a routine NRC inspection, a review of historical occupational dosimetry monitoring data for interventional radiology physician AUs was questioned regarding unexpectedly low results. This was interpreted to be an indicator of noncompliance with the wearing of occupational dose monitoring devices and, therefore, required occupation dose reconstructions in order to estimate the actual dose. In an effort to comply with dose monitoring requirements, the AU interventional radiologists diligently began wearing their whole-body and ring dosimeters during all procedures including Y-90, fluoroscopy-guided and CT-guided. In the interest of patient care, an AU that performs many interventional CT-guided procedures involving the use of a cumbersome treatment device, placed his hand in the CT beam on numerous occasions to stabilize the device. This quickly resulted in a cumulative extremity exposure that exceeded allowed limits. Once we became aware of the extremity over-exposure, steps were taken to prevent any further significant extremity exposure for the remainder of the year. The over-exposure was reported to the NRC and State following regulatory requirements.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"451 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122488028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young Andrew Yau-Wah, Yen Cheng-Yo, Hung Chil-Hsin
Conventional Head and Neck cancer treatment with primary surgical intervention is a relatively suffering manipulation because of causing severe facial deformity, and mastication malfunction, and resulted in a very poor quality of life for the patients afterward. And post-operation adjuvant therapy with combined modality treatment with Concurrent Chemo-Radio Therapy (CCRT) has been recommended approach for H&N cancer for decades too. But it is also relatively more toxic to the patient, and further severely disrupts patients’ quality of life due to systemic side-effects caused by intravenous cytotoxic drug delivery. Intra-arterial infusion chemotherapy is another option for CCRT because of not only a better tumor response documented, and also bonus a better quality of life improvement. The demonstrated H&N cancer patient approaching with Intra-Arterial Concurrent Chemo-Radio Therapy (IACCRT) showed a very satisfactory curative outcome. Besides the much better quality of life for the patient was conserved, it also bonuses to restore the patient’s dignity of life when compared to the conventional suffering surgical intervention. Such highly humanize IACCRT treatment modality for H&N cancer patients should be recommended and encouraged in clinical practice.
{"title":"Non-Surgical management with Intra-Arterial Concurrent Chemo Radio Therapy (IACCRT) can be a definitive organ preservation treatment for buccal cancer patient","authors":"Young Andrew Yau-Wah, Yen Cheng-Yo, Hung Chil-Hsin","doi":"10.17352/ijrro.000049","DOIUrl":"https://doi.org/10.17352/ijrro.000049","url":null,"abstract":"Conventional Head and Neck cancer treatment with primary surgical intervention is a relatively suffering manipulation because of causing severe facial deformity, and mastication malfunction, and resulted in a very poor quality of life for the patients afterward. And post-operation adjuvant therapy with combined modality treatment with Concurrent Chemo-Radio Therapy (CCRT) has been recommended approach for H&N cancer for decades too. But it is also relatively more toxic to the patient, and further severely disrupts patients’ quality of life due to systemic side-effects caused by intravenous cytotoxic drug delivery. Intra-arterial infusion chemotherapy is another option for CCRT because of not only a better tumor response documented, and also bonus a better quality of life improvement. The demonstrated H&N cancer patient approaching with Intra-Arterial Concurrent Chemo-Radio Therapy (IACCRT) showed a very satisfactory curative outcome. Besides the much better quality of life for the patient was conserved, it also bonuses to restore the patient’s dignity of life when compared to the conventional suffering surgical intervention. Such highly humanize IACCRT treatment modality for H&N cancer patients should be recommended and encouraged in clinical practice.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"410 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114943720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medulloblastoma is the most prevalent malignant brain tumor in children, accounting for roughly 15% to 20% of all malignancies of the Central Nervous System (CNS), for 40% of childhood, tumors are in the posterior fossa. Medulloblastoma is a heterogeneous combination of several subgroups with discrete characteristics, rather than a homogeneous illness. Genomic profiling of medulloblastomas revealed that the medulloblastoma may be further divided into four separate molecular subgroups. In this review, we aim to focus on the current state of understanding of the molecularity of the disease with a focus on genomic events that define the aforementioned subgroups and an overview of the molecular subtype of medulloblastoma upon discussing the following points (i) introduction to medulloblastoma and basic classification of the molecular subtype of medulloblastoma followed by their prevalence, age and gender discrimination, and specific molecular characterization. (ii) specific MRI features of the locality of a molecular subtype of medulloblastoma (iii) finally MRI distinguishable features for the identification of the specific molecular type. This review will enhance your knowledge regarding the subtype of medulloblastoma and the role of MRI in the identification of these subtypes.
{"title":"Overview of molecular subtype of medulloblastoma and role of MRI in their identification","authors":"Ayesha Binte Ashfaq, I. Aisha","doi":"10.17352/ijrro.000048","DOIUrl":"https://doi.org/10.17352/ijrro.000048","url":null,"abstract":"Medulloblastoma is the most prevalent malignant brain tumor in children, accounting for roughly 15% to 20% of all malignancies of the Central Nervous System (CNS), for 40% of childhood, tumors are in the posterior fossa. Medulloblastoma is a heterogeneous combination of several subgroups with discrete characteristics, rather than a homogeneous illness. Genomic profiling of medulloblastomas revealed that the medulloblastoma may be further divided into four separate molecular subgroups. In this review, we aim to focus on the current state of understanding of the molecularity of the disease with a focus on genomic events that define the aforementioned subgroups and an overview of the molecular subtype of medulloblastoma upon discussing the following points (i) introduction to medulloblastoma and basic classification of the molecular subtype of medulloblastoma followed by their prevalence, age and gender discrimination, and specific molecular characterization. (ii) specific MRI features of the locality of a molecular subtype of medulloblastoma (iii) finally MRI distinguishable features for the identification of the specific molecular type. This review will enhance your knowledge regarding the subtype of medulloblastoma and the role of MRI in the identification of these subtypes.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131820916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Imtiaz, Kumar K Ashok, Ajmal Rizwan, Khalid Danial, Shamim Bushra, Zaidi Mahum
Rosai-Dorfman disease is an uncommon benign non-Langerhans cell histiocytosis proliferative disorder. It commonly involves the lymph nodes and is classically presented with massive cervical lymphadenopathy. It can also involve the extra-nodal sites of the body and is reported in 43% of Rosai-Dorfman disease cases. The central nervous system is rarely involved in Rosai-Dorfman disease from which intra-cranial is more common than spinal lesions. An isolated dural-based intra-cranial Rosai-Dorfman disease is extremely rare. It usually mimics meningioma on radiological imaging. It is very difficult to diagnose the Rosai-Dorfman disease on imaging and intra-operative appearances of the lesion. We present a histopathologically proven case of an isolated Rosai-Dorfman disease involving the central nervous system in 49 years old female patient which was radiologically mimicking the meningioma.
{"title":"An isolated intra-cranial rosai-dorfman disease radiologically mimicking the meningioma","authors":"A. Imtiaz, Kumar K Ashok, Ajmal Rizwan, Khalid Danial, Shamim Bushra, Zaidi Mahum","doi":"10.17352/ijrro.000047","DOIUrl":"https://doi.org/10.17352/ijrro.000047","url":null,"abstract":"Rosai-Dorfman disease is an uncommon benign non-Langerhans cell histiocytosis proliferative disorder. It commonly involves the lymph nodes and is classically presented with massive cervical lymphadenopathy. It can also involve the extra-nodal sites of the body and is reported in 43% of Rosai-Dorfman disease cases. The central nervous system is rarely involved in Rosai-Dorfman disease from which intra-cranial is more common than spinal lesions. An isolated dural-based intra-cranial Rosai-Dorfman disease is extremely rare. It usually mimics meningioma on radiological imaging. It is very difficult to diagnose the Rosai-Dorfman disease on imaging and intra-operative appearances of the lesion. We present a histopathologically proven case of an isolated Rosai-Dorfman disease involving the central nervous system in 49 years old female patient which was radiologically mimicking the meningioma.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114757888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case report aimed to evaluate the sonographic usefulness of gray-scale transrectal ultrasound (TRUS), transabdominal prostate ultrasound (TAPUS) and post-void residual (PVR) urine volume in the detection of an enlarged prostate. Benign prostate hypertrophy(BPH) is a common complaint in older men with clinical outcomes such as urinary hesitancy, bladder distention, and other signs of bladder outlet obstruction. The case presented describes a patient with urinary symptoms associated with an enlarged prostate and bladder obstruction. The results show that an enlarged prostate and bladder disease may be evaluated using post-void residual urine measurement of the bladder, abdominal prostate ultrasound and evaluation of the prostate using the transrectal ultrasound method. This case report will make an essential contribution to the existing literature and can enhance positive social changes by providing an in-depth understanding of the diagnostic capabilities of ultrasound technology in the evaluation of BPH.
{"title":"The Prognostic Value of Post-Void Residual Urine Volume, Abdominal Prostate and Transrectal Prostate Ultrasound for Complication of Benign Prostate Hyperplasia: A Case Report Sonographic Analysis","authors":"I. N. Malu","doi":"10.17352/IJRRO.000032","DOIUrl":"https://doi.org/10.17352/IJRRO.000032","url":null,"abstract":"This case report aimed to evaluate the sonographic usefulness of gray-scale transrectal ultrasound (TRUS), transabdominal prostate ultrasound (TAPUS) and post-void residual (PVR) urine volume in the detection of an enlarged prostate. Benign prostate hypertrophy(BPH) is a common complaint in older men with clinical outcomes such as urinary hesitancy, bladder distention, and other signs of bladder outlet obstruction. The case presented describes a patient with urinary symptoms associated with an enlarged prostate and bladder obstruction. The results show that an enlarged prostate and bladder disease may be evaluated using post-void residual urine measurement of the bladder, abdominal prostate ultrasound and evaluation of the prostate using the transrectal ultrasound method. This case report will make an essential contribution to the existing literature and can enhance positive social changes by providing an in-depth understanding of the diagnostic capabilities of ultrasound technology in the evaluation of BPH.","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127286768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast conserving surgery and intra-operative specimen radiography: Margin assessment by the surgeon or the radiologist?","authors":"Mylvaganam Senthurun","doi":"10.15761/rdi.1000134","DOIUrl":"https://doi.org/10.15761/rdi.1000134","url":null,"abstract":"","PeriodicalId":166621,"journal":{"name":"International Journal of Radiology and Radiation Oncology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128052503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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