Cutaneous Metastasis refers to a growth of neoplastic cells in the skin originating from an internal malignancy. Morphologically the metastasis could take multiple morphologies. We report a case of cutaneous metastasis in a female of age 34 years. She initially presented with a 2 years history of progressive appearance of multiple asymptomatic clusters of monomorphic papulonodular lesions widespread on her trunk, lower limbs and genitalia later developed dyspnoea and weight loss. Chest CT showed moderate pleural effusion and multiple lymphadenopathies and right sided lung mass/consolidation. Histopathological evidences of cutaneous biopsy revealed cutaneous metastasis consistent with the lung primary.
{"title":"Crops of Papules and Papulonodular Plaques- An Unusual Presentation of Cutaneous Metastasis- A Case Report","authors":"Z. S. Chaudhry, A. Ghias, A. Asghar, T. Ahmad","doi":"10.23880/cdoaj-16000221","DOIUrl":"https://doi.org/10.23880/cdoaj-16000221","url":null,"abstract":"Cutaneous Metastasis refers to a growth of neoplastic cells in the skin originating from an internal malignancy. Morphologically the metastasis could take multiple morphologies. We report a case of cutaneous metastasis in a female of age 34 years. She initially presented with a 2 years history of progressive appearance of multiple asymptomatic clusters of monomorphic papulonodular lesions widespread on her trunk, lower limbs and genitalia later developed dyspnoea and weight loss. Chest CT showed moderate pleural effusion and multiple lymphadenopathies and right sided lung mass/consolidation. Histopathological evidences of cutaneous biopsy revealed cutaneous metastasis consistent with the lung primary.","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"2 1","pages":"207-211"},"PeriodicalIF":0.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87574497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-03DOI: 10.1007/springerreference_109785
Farhana Muzaffar
{"title":"Non-Langerhans cell histiocytoses","authors":"Farhana Muzaffar","doi":"10.1007/springerreference_109785","DOIUrl":"https://doi.org/10.1007/springerreference_109785","url":null,"abstract":"","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"21 1","pages":"161-163"},"PeriodicalIF":0.0,"publicationDate":"2017-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81647661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-24DOI: 10.1097/00000542-196607000-00056
V. Mehta, Abishek De, C. Balachandran
Hyperbaric O 2 therapy (HBOT) or hyperoxygenation is a method of administering pure O 2 at a higher atmospheric pressure in a pressurized chamber in order to treat a medical condition. This review focuses on the mechanism of action, treatment protocol, indications and the contraindications of hyperbaric oxygen therapy.
{"title":"Hyperbaric oxygen therapy","authors":"V. Mehta, Abishek De, C. Balachandran","doi":"10.1097/00000542-196607000-00056","DOIUrl":"https://doi.org/10.1097/00000542-196607000-00056","url":null,"abstract":"Hyperbaric O 2 therapy (HBOT) or hyperoxygenation is a method of administering pure O 2 at a higher atmospheric pressure in a pressurized chamber in order to treat a medical condition. This review focuses on the mechanism of action, treatment protocol, indications and the contraindications of hyperbaric oxygen therapy.","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"11 1","pages":"164-167"},"PeriodicalIF":0.0,"publicationDate":"2016-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78302984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-24DOI: 10.1007/springerreference_41823
Farid-ur-Rehman, G. Hussain
{"title":"Michelin tire syndrome","authors":"Farid-ur-Rehman, G. Hussain","doi":"10.1007/springerreference_41823","DOIUrl":"https://doi.org/10.1007/springerreference_41823","url":null,"abstract":"","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"14 1","pages":"109-111"},"PeriodicalIF":0.0,"publicationDate":"2016-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84367641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-22DOI: 10.5505/SAKARYAMEDJ.2016.52385
Erdal Pala, R. I. Engin, Erdem Geçer
Terra firma-forme dermatosis (TFFD) is a recently described cutaneous pigmentation disorder. It is a bizarre, acquired and idiopathic dermatosis and is characterized by brown, dirt-like discoloration that cannot be removed by bathing with water or rubbed off with routine detergent soap, but can be removed by isopropyl alcohol. A 20-year-old male came for treatment of chickenpox. Incidentally we observed multiple hyperpigmented plaques on the trunk and back, which disappeared on rubbing with isopropyl alcohol. He had normal washing habits and lesions disappeared after scrub bath. We propose scrub bath as one of the treatment modality.
{"title":"Terra firma-forme dermatosis","authors":"Erdal Pala, R. I. Engin, Erdem Geçer","doi":"10.5505/SAKARYAMEDJ.2016.52385","DOIUrl":"https://doi.org/10.5505/SAKARYAMEDJ.2016.52385","url":null,"abstract":"Terra firma-forme dermatosis (TFFD) is a recently described cutaneous pigmentation disorder. It is a bizarre, acquired and idiopathic dermatosis and is characterized by brown, dirt-like discoloration that cannot be removed by bathing with water or rubbed off with routine detergent soap, but can be removed by isopropyl alcohol. A 20-year-old male came for treatment of chickenpox. Incidentally we observed multiple hyperpigmented plaques on the trunk and back, which disappeared on rubbing with isopropyl alcohol. He had normal washing habits and lesions disappeared after scrub bath. We propose scrub bath as one of the treatment modality.","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"41 1","pages":"52-54"},"PeriodicalIF":0.0,"publicationDate":"2016-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78047644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives To document various biochemical parameters like serum calcium, uric acid etc. and correlate them clinically. Patients and methods An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proven psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results There were significant alterations in different biochemical values in patients before and after treatment. With clinical improvement there was shift of biochemical parameters towards normal value. Hyperuricemia was seen in 16% patients and hypocalcaemia was seen in 10% of patients. Conclusions With improvement of clinical picture, a shift of biochemical values towards normal was recorded.
{"title":"A STUDY OF CLINICAL AND BIOCHEMICAL CORRELATION IN PATIENTS OF PSORIASIS IN ACUTE EXACERBATION","authors":"N. Puri, B. Mahajan","doi":"10.7241/ourd.20142.32","DOIUrl":"https://doi.org/10.7241/ourd.20142.32","url":null,"abstract":"Objectives To document various biochemical parameters like serum calcium, uric acid etc. and correlate them clinically. Patients and methods An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proven psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results There were significant alterations in different biochemical values in patients before and after treatment. With clinical improvement there was shift of biochemical parameters towards normal value. Hyperuricemia was seen in 16% patients and hypocalcaemia was seen in 10% of patients. Conclusions With improvement of clinical picture, a shift of biochemical values towards normal was recorded.","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"24 1","pages":"236-240"},"PeriodicalIF":0.0,"publicationDate":"2014-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74078455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To document the causes and clinical and histopathological features of cicatricial alopecia. Patients and methods A study of 40 patients was conducted to study the clinical variants and histopathology of cicatricial alopecia. Results In our study, major causes of cicatricial alopecia were lichen planopilaris (27.5%), discoid lupus erythematosus (25%), pseudopelade of Brocq (20%), systemic lupus erythematosus (5%) followed by scleroderma, dermatomyositis, keratosis follicularis spinulosa decalvans, aplasia cutis, kerion, follicular mucinosis, pemphigus, dissecting cellulitis of scalp/ pyogenic folliculitis and acne keloidalis nuchae in 2.5% cases each. Morphological features included epidermal atrophy in 90%, erythema in 55%, follicular plugging in 40%, telangiectasia in 27.5%, diffuse scaling in 25% and mottled hyperpigmentation in 20% patients. The commonest histopathological features were perifollicular fibrosis in 65%, basal cell vacuolization in 52.5%, perifollicular lymphocytic infiltrate in 50%, epidermal atrophy in 35% and hyperkeratosis in 20% patients. Conclusion Lichen planopilaris, discoid lupus erythematosus, pseudopelade of Brock were the common causes of cicatricial alopecia in the studied population.
{"title":"A clinical and histopathological study of cicatricial alopecia","authors":"N. Puri","doi":"10.7241/OURD.20133.75","DOIUrl":"https://doi.org/10.7241/OURD.20133.75","url":null,"abstract":"Objective To document the causes and clinical and histopathological features of cicatricial alopecia. Patients and methods A study of 40 patients was conducted to study the clinical variants and histopathology of cicatricial alopecia. Results In our study, major causes of cicatricial alopecia were lichen planopilaris (27.5%), discoid lupus erythematosus (25%), pseudopelade of Brocq (20%), systemic lupus erythematosus (5%) followed by scleroderma, dermatomyositis, keratosis follicularis spinulosa decalvans, aplasia cutis, kerion, follicular mucinosis, pemphigus, dissecting cellulitis of scalp/ pyogenic folliculitis and acne keloidalis nuchae in 2.5% cases each. Morphological features included epidermal atrophy in 90%, erythema in 55%, follicular plugging in 40%, telangiectasia in 27.5%, diffuse scaling in 25% and mottled hyperpigmentation in 20% patients. The commonest histopathological features were perifollicular fibrosis in 65%, basal cell vacuolization in 52.5%, perifollicular lymphocytic infiltrate in 50%, epidermal atrophy in 35% and hyperkeratosis in 20% patients. Conclusion Lichen planopilaris, discoid lupus erythematosus, pseudopelade of Brock were the common causes of cicatricial alopecia in the studied population.","PeriodicalId":16680,"journal":{"name":"Journal of Pakistan Association of Dermatology","volume":"28 1","pages":"272-276"},"PeriodicalIF":0.0,"publicationDate":"2013-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80707656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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