Chen Wu, Shihao Ran, Henry Le, Manmohan Singh, I. Larina, D. Mayerich, M. Dickinson, K. Larin
Both optical coherence tomography (OCT) and selective plane illumination microscopy (SPIM) are frequently used in mouse embryonic research for high-resolution three-dimensional imaging. Each of these imaging methods provide a unique and independent advantage: SPIM provides morpho-functional information through immunofluorescence and OCT provides a method for whole-embryo 3D imaging. In this study, we have combined rotational imaging OCT and SPIM into a single, dual-modality device to image E9.5 mouse embryos. The results demonstrate that the dual-modality setup is able to provide both anatomical and functional information simultaneously for more comprehensive tissue characterization.
{"title":"A dual-modality optical coherence tomography and selective plane illumination microscopy system for mouse embryonic imaging","authors":"Chen Wu, Shihao Ran, Henry Le, Manmohan Singh, I. Larina, D. Mayerich, M. Dickinson, K. Larin","doi":"10.1117/12.2252677","DOIUrl":"https://doi.org/10.1117/12.2252677","url":null,"abstract":"Both optical coherence tomography (OCT) and selective plane illumination microscopy (SPIM) are frequently used in mouse embryonic research for high-resolution three-dimensional imaging. Each of these imaging methods provide a unique and independent advantage: SPIM provides morpho-functional information through immunofluorescence and OCT provides a method for whole-embryo 3D imaging. In this study, we have combined rotational imaging OCT and SPIM into a single, dual-modality device to image E9.5 mouse embryos. The results demonstrate that the dual-modality setup is able to provide both anatomical and functional information simultaneously for more comprehensive tissue characterization.","PeriodicalId":168343,"journal":{"name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123457315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.1109/icter.2013.6761146
H. J. Kim, Munish Chauhan, A. K. Kasinadhuni, A. Minhas
Provides an abstract for each of the tutorial and workshop presentations and a list of presenters. The complete presentations were not made available for publication as part of the conference proceedings.
提供每个教程和研讨会演示文稿的摘要以及演示文稿列表。完整的发言没有作为会议记录的一部分提供出版。
{"title":"Workshops and tutorials","authors":"H. J. Kim, Munish Chauhan, A. K. Kasinadhuni, A. Minhas","doi":"10.1109/icter.2013.6761146","DOIUrl":"https://doi.org/10.1109/icter.2013.6761146","url":null,"abstract":"Provides an abstract for each of the tutorial and workshop presentations and a list of presenters. The complete presentations were not made available for publication as part of the conference proceedings.","PeriodicalId":168343,"journal":{"name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134230524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}